Objective:To investigate the expression of LAIR-1 on Treg cells and TGF-βin the peripheral blood of patients with oral lichen planus(OLP).Methods:The peripheral blood was obtained from 22 OLP patients and 22 healthy controls.Flow cytometry was used to evaluate the proportion of LAIR-1 on CD4 +Foxp3 +Treg cells,and the level of TGF-βwas measured by ELISA.Results:In the peripheral blood of OLP patients,the proportion of LAIR-1 on CD4 +Foxp3 +Treg cells and TGF-βcontent were significantly higher than those of the healthy controls(P ＜0.05),The proportion of LAIR-1 on CD4 +Foxp3 +Treg cells was positively correlated with the level of TGF-β(r =0.43,P ＜0.05).Conclusion:The high expression of LAIR-1 on CD4 +Foxp3 +Treg cells and TGF-βin the pe-ripheral blood of OLP patients may be responsible for the pathogenesis of OLP.

Objective : To investigate the clinical effects of different restoration methods on large area defect of deciduous molars. Methods : A total of 150 deciduous molars were selected and randomly divided into three groups: A, B and C. Group A was repaired with glass ionomer and compound resin, B group was repaired by Hall technique, and C group was repaired with metal preformed crown. The successful rate of restoration in 6 and 12 months was compared between the three groups. Results: There was no significant difference between three groups in A, B and C (P > 0.05) in 6 months; the successful rate of 12 months repair in group B and C was significantly higher than that in group A (P < 0.05). Conclusion The success rate of Hall technique and metal performed crown is higher than that of glass ionomer and composite resin on the repair of large defects of deciduous molars.