1.Long-Term Effects of Partial Axillary Dissection in Modified Radical Mastectomy of Breast Cancer
Chinese Journal of Bases and Clinics in General Surgery 2008;0(07):-
0.05).The incidence of upper limb edema and dysfunction was 4.2%(2/48) in PALD group and 16.0%(8/50) in TALD group(P0.05).Conclusion PALD may reduce upper limb dysfunction after operation in patients with stage Ⅰ and Ⅱ breast cancer,and does not increase prognostic risk.
2.A dynamic filter while using dual unipolar pulse excitation in digital ultrasound imapng system
International Journal of Biomedical Engineering 2009;32(2):95-98
Objective This paper analyzes the spectrum of ultrasonic echo and its change with depth when using dual unipolar pulse excitation.Methods According to the theory of matched filter,a group of aynmic filter was designed to ensure the near-field image resolution while maintaining the sensitivity of far-field image.Results This filter was accomplished in FPGA chip.Conclusion Higher image quality Can obtained applying this filter in the au-digital ultrasonic imaging system compared with those using constant filter.
3.Application and Immune Effect of Nutrison-5Fu on Perioperative Patients with Progressive Gastrointestinal Cancer
Lilin MA ; Yuquan CHEN ; Hongxing CHEN
Journal of Chinese Physician 2001;0(01):-
Objectives To investigate and evaluate the effect of Nutrison-5Fu on immune function of perioperative patients with progressive gastrointestinal cancer,and simultaneously we also recommended the methods of application of Nutrison-5Fu.Methods Seventy eight cases were equally divided at random into three groups,26 cases in each group.⑴Nutrison-5Fu group:the patients were treated with Nutrison-5Fu.⑵Chemotherapy group:the patients only received 5-Fu.⑶Control group:there were not any chemotherapy and immunetherapy during the perioperation.The values of CD 3,CD 4,CD 8 and NKCC were determined in all cases.Results Values of CD 3,CD 4,CD/CD 8 ratio and NKCC in most patients were distinctly low,but the condition rapid improved by giving them Nutrison-5Fu.On the contrary,the values declined further after chemotherapy alone.Conclusion The treatment of Nutrison-5Fu not only can repress the development of the tumor,but also can improve the dystrophic status and immune function of the patients with cancer.
5.Progress in megnetic nanobead preparation and application in bio-mediacal engineering
Zikai ZHAO ; Guohua HUI ; Yuquan CHEN
International Journal of Biomedical Engineering 2009;32(3):183-185,189
As a novel functional material with great application values, magnetic nanobead has been in fast development in recent years. Magnetic nanobead is provided with characteristics of beth polymeric and mag-netic particles, so it can be detected easily fi'om the medium and can be easily located since they can move di-rectionally when motivated by external electric field. The magnetic nanobead is widely used in biomedical engi-neering research due to its unique physical and chemical properties which simplify the complex experiments op-erations and shorten the testing period.
6.CLINICAL SIGNIFICANCE OF CD62P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH NON-SMALL CELL LUNG CANCER BY FLOW CYTOMETRY
Qingyong CHEN ; Yuquan WU ; Li YAN
Medical Journal of Chinese People's Liberation Army 2001;0(10):-
To assess the expression of peripheral blood CD62P in patients with non-small cell lung cancer and its clinical significance, peripheral blood CD62P content in 75 patients with lung cancer was detected by immune-flow-cytometry. Among them 45 patients with lung cancer were subjected to comparison of the CD62P contents between pre-operation and post-operation, and comparison with those of 30 normal donors. The results showed that peripheral blood CD62P content in patients with lung cancer was significantly higher than that in normal con-trols(P
7.Effect of verapamil on the alteration of phospholipase A_2 activity in acute pancreatitis rats
Xinze ZHOU ; Qinsheng MAO ; Yuquan CHEN ;
Chinese Journal of General Surgery 1997;0(04):-
Objective To evaluate activity alteration of the pancreatic tissue phospholipase A 2 (PLA 2) and the therapeutic effects of verapamil in acute pancreatitis (AP) rats. Methods After the model of AP in the rat was established by the closed duodenal loop technique, the changes of PLA 2 activity were observed, and the pancreatic histology was examined by light and electron microscopy. Results At 16 and 24 hours after induction of AP in rats, significant inhibition of PLA 2 avtivity in pancreatic tissue was shown in the treated group (32.34?3.87, 35.26?4.52) as compared with AP group (44.83?5.31,47.77?5.86). The treated animals also showed decreasing in the severity of pancreatic pathology. Conclusions In AP rats exist high activity of PLA 2. Verapamil, a calcium channel blocker, might have therapeutic effects on AP by inhibiting the activity of PLA 2.
8.Depth of sedation induced by target-controlled infusion of propofol required to inhibit swallowing reflex
Qinyan YANG ; Xinjie ZHU ; Yuquan CHEN
Chinese Journal of Anesthesiology 2012;32(6):722-723
ObjectiveTo determine the depth of sedation induced by target-controlled infusion (TCI) of propofol required to inhibit the swallowing reflex.MethodsThirty-five ASA Ⅰ or Ⅱ healthy volunteers,aged 20-60 yr,with body mass index < 30 kg/m2,were enrolled in the study.Sedation was performed with TCI of propofol.The initial target plasma concentration (Cp) of propofol was set at 2.4 μg/ml and the Cp increased or decreased by 0.2 μg/ml every 5 min until the BIS value reached the predetermined level.The initial Cp of propofol was increased or decreased by 0.3 μg/ml in the next subject according to the BIS value in the previous one.The up-and-down sequential experiment was pedormed.The BIS value was set at 65 in the first subject and the ratio of the BIS value between the two consecutive subjects was 1.1.The BIS value was increased or decreased depending on the occurrence of the swallowing reflex in the previous subject.The half-effective BIS value (BIS50) and 95%confidence interval (CI) of propofol inhibiting the swallowing reflex were calculated by up-and-down sequential method.ResultsThe BIS50 of propofol required to inhibit the swallowing reflex was 64.4 (95% CI 59.3-69.8).ConclusionThe BIS50 and 95% CI of propofol administered by TCI and required to inhibit the swallowing reflex is 64,4 (59.3-69.8).
9.Advances in radio frequency identification sensor network
Hao YANG ; Xiaohe YANG ; Yuquan CHEN
International Journal of Biomedical Engineering 2006;0(06):-
Radio frequency identification sensor network, a technique integrating radio frequency identification (RFID) with wireless sensor network (WSN), is introduced. The basic structure of RFID sensor network is analyzed at first. Then components of RFID sensor and relevant supporting techniques including thin film battery, quartz crystal microbalance (QCM) and surface acoustic wave (SAW) are discussed. Research status and foregrounds of both domestic and international researches are introduced as well as applications in different fields.
10.THE EFFECTS OF COMPOUND ANTI-TUMOR GRANULES ON GROWTH INHIBITION AND EXPRESSION OF p53 AND PCNA IN MICE BEARING SARCOMA 180
Qingyong CHEN ; Yuquan WU ; Yongshen HE
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
To study the anti tumor effect of "Compound" granules on mice bearing sarcoma 180 and its possible mechanism, We observed the effect of "Compound" granules on tumor weight and expression of p53 and PCNA in mice bearing sarcoma 180 by means of immunohisto chemistry. After treatment with "Compound" anti tumor granules, anti tumor granules (Ⅰ,Ⅱ,Ⅲ) and CTX, the results showed that "Compound" granules and the other four drugs could inhibit sarcoma 180 growth to various extent, and the rates of inhibition were 20 31%, 6 56%, 15 0%, 19 06% and 30 3%, respectively. Meanwhile,we found the expression of p53 and PCNA in mice bearing sarcoma 180 was affected in various groups.It suggested that compound anti tumor granules had antitumor effect and its possible mechanism might be associated with inhibition the expression of mutate p53 and PCNA.