In this article,the professor WANG Li-zhong’s experiences was described,which use the Lipi method to treat the cold,cough,dazzling dizziness,insomnia,stomach pain.Professor WANG Li-zhong Consider that the normal spleen and stomach’s ying and wei are harmonious,and there is no phlegm producted.When the functions of five zang viscera are coordinate,the vital qi is sufficiently and the pathogenic qi can’t injury to the body.Lipi method incarnates the professor WANG Li-zhong’s views to the dieases,its unique to treatment in clinic,and the academic thoughts of treating preventable diseases in Chinese medcine.

OBJECTIVE:To investigate the implementing status of the Guiding Principles of Clinical Application of Antibacterials.METHODS:A total of 60 case histories of patients who had undergone thyroidectomy and discharged from hospital were selected in July 2005 from six third level hospitals(10 from each hospital) in Changsha and Guangzhou for a questionnaire survey and a statistical analysis based on Guiding Principles of Clinical Application of Antibacterials.RESULTS:The average hospital stay was(10.18?3.71) days;the average cost of hospitalization was(7 538.50?631.99) yuan and the average cost on antibacteirals was(705.21?91.10) yuan.The average compliance rates in the choice of drug kinds and medication opportunity were 35% and 80% respectively.The average medication duration was 6.38 days.CONCLUSION:The implementation of the Guiding Principles of Clinical Application of Antibacterials was far from ideal,thus the related department should offer training and tighten control on the use of antibacterials.

0 05) CONCLUSION:The health problems and rational use of drugs in the aged should be given more concerns,especially in the patients between the ages of 60 and 69 years The reason why the consultation rate of man is higher than that of women should be found out The use of injection preparations and the kinds of drug for combined use ought to be decreased

OBJECTIVE:To guide the rational use of anti-epileptic drugs(AEDs)in clinical practice.METHODS:In a retrospective review,there were733patients in Xuanwu hospital who suffered from poor curative effect or intoxication of AEDs from March2000to March2001.The results of blood concentration of anti-epileptic drugs(AEDs Css)were ana?lyzed.RESULTS:The Css of37.6%of the patients were within the normal Css range,and6.4%were higher and55.9%were lower than the normal.In combined use of AEDs and other drugs,79.1%of the patients had higher or lower Css than nor?mal.In addition,chemosynthetic components were detected in90%of the patients who took Chinese medicine.Among them,86%of the patients had abnormal Css.CONCLUSION:Css monitoring should be done when AEDs were administrated.It is advisable to use only one or two kinds of AEDs,and to pay attention of the chemosynthetic components in Chinese medicine.

OBJECTIVE:To explore an effective mode and way to quickly train on-the-job pharmacist to become clinical pharmacist in China.METHODS:With the reference to the process and current situation of clinical pharmacist training both domestically and abroad,the background,systems and policies about clinical pharmacist training were compared and the per?sonal working experience of the author was considered,then an efficient mode for domestic on-the-job pharmacist training was put forward.RESULTS&CONCLUSION:On-the-job pharmacist training in China should be carried out in steps,which includes theoretical study and clinical practice,establishment of evaluation system,and writing of scientific papers,only by doing this can we really train the clinical pharmacists in clinical practice,ensure the safe,rational,effective and economic medication and reduce the waste of health resources.

OBJECTIVE: To explore some effective training methods on the basic technical skills for community pharmacists. METHODS: The training content and method of technical skills for community pharmacists were arranged based on the basic condition of community pharmacists. The outcome of the training and examination of technical skills were obtained through skill examination of questionnaire survey. RESULTS: The majority of community pharmacists had a good mastering of the basic skills such as the standardized drug dispensing,drug consultation,collecting and reporting of adverse drug reactions. 95% of the pharmacists considered that this kind training was helpful for their practical work. CONCLUSION: The key to improve community pharmaceutical professional staff’s knowledge and service level is to establish regular training and examination on basic technical skills.

OBJECTIVE: To explore the methods for clinical pharmacists to carry out education in asthmatic patients.METHODS: The necessities for clinical pharmacist to provide education for asthmatic patient were analyzed and the specific modes were designed.RESULTS & CONCLUSION: As a member in the clinical staff,clinical pharmacist should attend the team actively to carry out effective pharmaceutical education in patients so as to raise patients' compliance,improve therapeutic effect and reduce incidence of adverse drug reactions.

OBJECTIVE:To explore the components and style of the intervention performed by clinical pharmacists to facilitate communication between pharmacists and physicians. METHODS: The data about clinical pharmacists' medication intervention and the follow-up results on ICU physicians in general surgery department during Nov. in 2007 were collected for statistical analysis with regard to the components and style of the intervention. RESULTS: The components of clinical pharmacists' medication intervention included dosage and administration (36.1%),whether the drug use was in line with indications (27.8%),assessment on adverse drug reactions (22.2%). The style of intervention included timely intervention and delayed intervention,and 50%～66.7% of the timely intervention and 90.1%～100% of the delayed intervention were accepted by physicians. CONCLUSION: The intervention of clinical pharmacists should be based on sound evidence and reasons,meanwhile,an appropriate style should be adopted in communicating with physicians so as to improve its accepting rate by physicians.

Objective:To establish a method for the determination of atractylodin, magnolol and honokiol in Xiangshapingwei pills by GC. Methods:An HP-5 column (30 m × 0. 32 mm × 0. 25 μm) with an FID detector was used, and the flow rate of the carrier gas (N2) was 2. 0 ml·min-1. The column temperature was raised by program: the initial temperature was 100℃ and maintained for 7 min, and then raised to 250℃ at the rate of 20℃·min-1 and kept for 10min. The inlet temperature was 300℃ and the detector tem-perature was 300℃. The injection volume was 1 μl and the split ratio was 20∶ 1. Results:The linear range of atractylodin, magnolol and honokiol was 4. 264-85. 280 μg·ml-1(r=0. 999 7), 9. 856-197. 120 μg·ml-1(r=0. 999 5) and 10. 040-200. 800 μg·ml-1 (r=0. 999 6), respectively. The average recovery wsa 98. 2%, 98. 6% and 99. 3% with RSD of 1. 5%, 1. 5% and 1. 9%, respec-tively (n=6). Conclusion:The method is simple, accurate and reliable, which can be used for the quality control of Xiangshaping-wei pills.

Aim To investigate the effects of PB-19 on action potential (AP) of ventricular cells in vitro and ischemia and reperfusion induced arrhythmias in vivo in rats. Methods ① We established the model of isolated rat right ventricular wall and perfused the models with normal Tyrode’s solution and PB-19.Microelectrode was inserted into the cells to record the AP. ② We ligated the left anterior descending coronary artery of rats to study the effects of PB-19 on ischemia and reperfusion induced arrhythmias. 50 rats were divided into 5 groups randomly and were given iv. injection with normal saline and PB-19 of different concentrations respectively. We recorded Ⅱ ECG of the rats. Results ①In vitro models, the APD_ 50、APD_ 90 of PB-19 group were significantly longer than that of control group respectively (P