BACKGROUND:Dislocation is a common short-term complication after total hip arthroplasty. Many factors can induce dislocation. Among controlable factors, the diameter of the femoral head may be one of factors affecting the incidence of dislocation. Generaly, large prosthesis meets the biomechanical feature of hip joint, and can increase the joint stability. OBJECTIVE:To observe the effects of different diameters of the femoral head on range of motion of the hip joint during primary total hip arthroplasty so as to provide evidence for selecting the prosthesis with an ideal diameter. METHODS: We colected data of 77 cases (87 hips), who underwent primary total hip arthroplasty with the femora head of 28 mm and 32 mm diameter in the Department of Orthopedics, Inner Mongolia Autonomous Region Wulanchabu Central Hospital from August 2009 to August 2012. Hip prosthesis was provided by ZIMMER Company. The hip motion interface was made from polyethylene on metal. The femoral head prosthesis was used as folows: 28 mm diameter in 51 hips, and 32 mm diameter in 36 hips. Posterior approach was utilized. Range of motion of hip internal rotation and external rotation to dislocation was measured at hip flexion 90° during the operation, and compared between different diameter groups. RESULTS AND CONCLUSION:The method of surgery was not changed during operation in al patients. No significant difference in the sum of degree at dislocation was detected between two different diameter groups (P > 0.05). No significant difference in the intraoperative range of motion during total hip arthroplasty was visible in patients with femoral neck fracture between the two different diameter groups (P > 0.05). No significant difference in the intraoperative range of motion during total hip arthroplasty was visible in patients with avascular necrosis of the femoral head between the two different diameter groups (P > 0.05). These data suggested that compared with the femoral head of 28 mm diameter, the femoral head of 32 mm diameter did not increase the range of motion during total hip arthroplasty. After operation, two kinds of femoral head did not affect the dislocation after total hip arthroplasty in 2-year folow-up.

Objective To explore the effect of the meteorologic factors on air pollution in the summer in Xian, China. Methods The data of SO2?NO2 and PM10 concentrations in the air and the related meteorologic factors [maximum temperature(tmax), minimum temperature(tmin), average air pressure(P) and relative humidity(H)) from April 1st to June 30th in 2005 were collected. The correlation between the air pollutant level and related meteorologic factors was analyzed by the elements time diagram and multiple regression models with SPSS 11.0 software. Results A significant correlations between the meteorological elements and air pollutants was seen, the regression models for air pollutants were as follows, lnSO2=-3.352+0.019 tmax-0.026 tmin, lnNO2=-3.448-0.003H+0.012 tmax-0.015 tmin and lnPM10=-2.197+0.011 tmax-0.021 tmin. Conclusion The meteorologic factors have some effects on the air pollution levels and then impact human health in some degree.

This article introduces the experience of CHEN Ying-yi, chief physician and one of the teacher of the fourth group of inheriting academic experience of veteran TCM experts of China, in treating perimenopausal women’s dysfunctional uterine bleeding. Chen holds that the basic pathogenesis of perimenopausal dysfunctional uterine bleeding is kidney deficiency with fever or stagnation. Treatment should focus on replenishing kidney and using the traditional Chinese drug by stages. The methods of stopping bleeding, clearing origin and reinstating the status quo are used flexibly. In clinic, it should grasp the key points of syndrome differentiation, and modify the therapy in accordance with the symptoms. Validated by clinical application, Chen’s experience has satisfactory curative effect and reference values for the treatment of perimenopausal women’s dysfunctional uterine bleeding.

Objective To study imageology anatomy concerned of sellar turica and explore its potential role on growth of pituitary adenomas. Methods According to classification of sinus sphenoidalis,103 normal imageology data of sellar turica region were analyzed, including 83 cases with entire saddle type sinus sphenoidalis and 20 cases anti-saddle type sinus sphenoidalis. Furthermore, the clinical data of 45 cases of pituitary adenomas with extension into sinus sphenoidalis were retrospectively studied. Results The relationship between sellar floor's shapes and sinus sphenoidals'types was that the larger the sinus sphenoidalis was, the deeper the floor was(98.8%). The relationship between sellar floor's shapes and the superior surface of hypophysis was that most of depressed sellar floors were companied with depressed superior surfaces of hypophysises(93.8%). The anteroposterior shapes of sellar turica in midsagittal can be divided into 4 types such as bag-type, kettle-type, tube-type, and sifter-type. 45 patients suffering from pituitary adenoms with extension into sinus sphenoidalis all had entire saddle type sinus sphenoidalis. Conclusions The imageology anatomy concerned of sellar turica could explain the phenomena of pituitary adenomas with extension toward sellar floor and sinus sphenoidalis. Referring to the literatures concerned, it indicated that the imageology anatomy was the key factor of affecting the growth of pituitary adenomas.

Object To study the microwave assisted procedure for the extraction of baicalin from root of Scutellariae baicalensis Georgi Methods An MSP 100D domestically made microwave sample preparation system with a maximum power of 850 watts was used. The effects of solvents, pressure/temperature of solvents and microwave radiation time on the yield of baicalin were studied by orthogonal experimental design. Results The optimal experimental conditions were extraction at 70% of microwave power with 30 times of 35% ethanol at a constant heating pressure/temperature of 0.15 MPa for 30 s. Conclusion The microwave assisted extraction not only takes a shorter time with better parallel results, but also gave an increased yield of about 10% as compared with ultrasonic extraction.

Objective To observe the expression levels of CD174, cyclin D1 and cyclin E in gastrointestinal tumor tissues, analyze the correlation among CD174, cyclin D1 and cyclin E, and evaluate the expression level of CD174 for diagnosis and prognosis of gastrointestinal tumors.Methods Flow cytometry was used to determine the expression of CD174, cyclin D1 and cyclin E on surface of the cells which were collected from the tumor tissues and distant part beside the same tumor and suspended. The expression and topography of CD174 in gastrointestinal tissue were investigated with immunohistochemical staining.Results The expression of CD174 in tumor tissues was obviously lower than that in distal noncancerous tissues (P

In the clinic postgraduate cultivation,the student-centralized teaching philosophy claims to elevate students’ activeness,develop their leading function sufficiently,carry out students-centralized and teachers-assisted case discussion,and meanwhile proceed phase tests. In this way,it is profitable for improving students’ ability of thinking and teaching effectiveness.

OBJECTIVE:To investigate the association of Cytochrome P4503A family polypeptide 5 [(CYP)3A5] and IL-10 poly-morphisms with the concentration/dose(C/D) ratio of tacrolimus in lung transplantation recipients. METHODS:CYP3A5 polymor-phisms at rs774746 and IL-10 polymorphisms at rs1800896 from peripheral blood cell of 51 lung transplant recipients was detected by Se-quenom MassArray iPLEX GOLD system. The relationship between gene polymorphism and tacrolimus C/D ratio was analyzed. RE-SULTS:The tacrolimus C/D ratio of the recipients who carried CYP3A5 rs776746 GG genotype were higher than those with AA+GG genotype,with statistical significance(P<0.01). The tacrolimus C/D ratio of the recipients who carried IL-10 rs1800896 AA genotype were higher than those with AG genotype during 1 week and 2 weeks after transplantation,with statistical significance(P<0.05). Com-bined analysis of these two genes,the tacrolimus C/D ratio of the recipients who carried more fast metabolic alleles were higher than those who didn't carry fast metabolic alleles,with statistical significance(P<0.01). CONCLUSIONS:Determination of recipients CYP3A5 at rs 776746and IL-10 at rs800896 genotype may be performed prospectively to help individualizing tacrolimus dose regimen.

Objective To establish a TaqMan real-time PCR assay for the detection of encephalo-myocarditis virus ( EMCV) .Methods Based on the conservative region of 3D gene of EMCV published in GenBank , a pair of primers and one TaqMan probe were designed and synthesized .Then a TaqMan real-time PCR assay was set up and the reactive system was optimized .The sensitivity and specificity of the assay was evaluated respectively .The TaqMan real-time PCR assay was then carried out to detect 98 randomly selected swine serum samples and the results were compared with those by using ELISA .Results The Ct value of the templates had a good linear relationship with the log starting quantity , with a correlation coefficient of 0.995.The TaqMan real-time PCR assay was only specific for EMCV and its sensitivity was 100 times higher than that of the ordinary PCR .The coincidence rate between the established assay and the ELISA assay was 98.0%in the detection of 98 blood samples.Conclusion The TaqMan real-time PCR assay for the detec-tion of EMCV was successfully established with advantages of high sensitivity and good specificity .It could be used for detection of EMCV and quantitative analysis .

Objective To evaluate the value and limitation of primary MSCT examination for rib fractures in a short interval. Methods Seventy-two cases with rib fractures were analyzed retrospectively.All of them underwent primary MSCT examination within the three days after trauma,and MSCT examination of chest,epigastria,rib or X-ray examination of rib for 1-6 times in the following 8 weeks.41 cases underwent X-ray examination firstly before MSCT examination.The total number of rib fractures was determined according to the compositive results of every examination.Diagnosis rate of the primary MSCT and X-ray examination were compared with each other.Results Among 72 cases,404 fractures in 325 ribs were diagnosed.Primary MSCT diagnosed 305 confirmed fractures and 28 doubtful fractures,and 84 fractures were not detected with diagnosis rate of 75.5%.13 of 28 suspected fractures were ruled out by the following re-examinations.The MSCT and X-ray diagnostic rates were 72.1%、50.3%,respectively for 41 cases who underwent X-ray examination firstly.Four fractures showed by X-ray plain film were not shown by primary MSCT.Conclusion There is a certain proportion of cases diagnosed as obscure or doubtful rib fracture by the primary MSCT. Therefore,diagnosis should be closely combined with the re-examination results of MSCT and X-ray plain film,especially MSCT ex-amination between the fourth and eighth weeks after trauma.