1.Scholars'consensus on the construction and development of chinese medical humanities:summary of"seminar on the construction of Chinese medical humanities"held in Harbin in August 2023
Jinfan WANG ; Mei YIN ; Yue WANG ; Huan LIU ; Zhong HE ; Yunzhang LIU ; Rui DENG ; Min CHEN ; Junrong LIU ; Yongfu CAO ; Donghong WANG ; Hongjiang ZHANG ; Fengxiang LU ; Yu CHENG ; Yuan HE ; Fang SHAN
Chinese Medical Ethics 2024;37(2):248-252
On August 2-4,2023,the"Third Summit Forum on'Building a Community of Shared Future for Doctors and Patients'"was jointly organized by institutions such as the Chinese Medical Ethics,the Hospital Humanities Management and Talent Training Special Committee of the China Population and Culture Promotion Association,Center for Ethical Studies of Renmin University of China,the Newspaper for China's Physicians,the China Health Law Society,the China Anti-Cancer Association,and the China Association For Ethical Studies in Harbin.The conference arranged a sub-forum for the"Seminar on the Construction of Chinese Medical Humanities",with domestic medical humanities scholars attending the conference.After heated discussions at the seminar,the Scholars'Consensus on the Construction and Development of Chinese Medical Humanities was formed.It was proposed that in the new era,it is urgent to build the medical humanities discipline,as well as lead the academic integration and development of medical humanities under the core socialist values.At the same time,for the construction of the medical humanities discipline,it is necessary to optimize the organizational mechanism,prosper and develop the overall framework of the medical humanities discipline,accelerate the construction of a professional teaching team for the medical humanities discipline,promote the establishment of a new carrier medical humanities education and teaching in cultivating morality and nurturing talents,as well as focus on solving problems related to the cultivation of medical humanities graduate students.
2.Current status and progress of artificial intelligence in endoscopic and imaging diagnosis of colorectal cancer
Xian ZHANG ; Qingguo WANG ; Yunzhang CHENG ; Chen HUANG
Chinese Journal of Digestive Surgery 2024;23(4):622-628
Colorectal cancer is a common malignant tumor of the digestive system globally, with both its incidence and mortality rates increasing annually in China. In recent years, there has been exponential growth in technology based on artificial intelligence, leading to significant advancements in the field of medical imaging diagnosis. Particularly in the application of colonoscopy, CT and magnetic resonance imaging (MRI), artificial intelligence, leveraging its advanced image recognition and feature analysis capabilities, has provided new perspectives for the diagnosis of colorectal cancer, thereby driving the realization of precision medicine. Currently, various artificial intelligence algorithms are either under development or optimization, such as performance comparisons of various artificial intelligence-assisted systems, the collaborative application of multiple algorithms, and integration with other omics. Additionally, challenges persist in the integration difficulty, interpre-tability and credibility, as well as cost and resource limitations of AI in clinical practice, necessitating further standardization and improvement. The authors explore the current status and progress of artificial intelligence in endoscopic and imaging diagnosis of colorectal cancer from four aspects: colonoscopy, CT, MRI and other imaging examination for reference and reference by peers.
3.Research progress in deep learning-based digital mammography for accurate diagnosis of breast clustered microcalcification
Xuan YANG ; Aiping DONG ; Yunzhang CHENG ; Baosan HAN
International Journal of Biomedical Engineering 2024;47(5):497-503
Breast clustered microcalcification (BCM) is one of the most critical X-ray signs of early breast cancer. However, due to the fact that BCM is very tiny and hidden, and manual interpretation is susceptible to subjective factors such as visual fatigue, manual diagnosis of dense BCM based on X-images suffers from a low detection rate, high false-negative rate, and high recall rate. In recent years, with the continuous optimization innovation of deep learning algorithms, and advancements of computer hardware technology, new hope has been brought to accurate diagnosis of BCM, which is expected to realize the accurate assessment of individual breast cancer risk. In this review, the research progress of deep learning for accurate diagnosis of BCM was summarized, such as full-field digital mammography (FFDM), digital breast tomosynthesis (DBT) and contrast-enhanced mammography (CEM), as well as the future developments in this field were discussed.
4.Effects of Plaque Eccentricity on Biodegradable Polylactic Acid Stent Implantantion in Stenotic Vessels
Ting HE ; Yunzhang CHENG ; Chenzhao ZHANG ; Guohui WANG
Journal of Medical Biomechanics 2021;36(2):E245-E250
Objective To study the effect of plaque eccentricity on stent performance and stress distributions of artery and plaque during stent implantation in stenotic vessels. Methods The stent and idealized stenotic vessels were constructed, and 4 different eccentricities (0%, 20%, 40%, 60%) were attributed to the plaque. Then the stent recoil, stent foreshortening, and stress distributions of artery and plaque when the stent was expanded to the target displacement were analyzed by the finite element method. Results Along with the increase of plaque eccentricity, both stent recoil and stent foreshortening gradually grew. At the same time, the stress of artery and plaque also showed an increasing tread, and high-stress areas gradually approached the narrow side. The maximum von Mises stress of the plaque was much greater than that of the artery. Conclusions Plaque eccentricity had a certain effect on performance of the stent and stress distributions of stenotic vessels. In stent design, the geometry of the plaque should be considered to improve clinical effect of the stent in interventional treatment.
5.Influence of Fixation Methods on Fixation Effects of Femoral Neck Fracture
Wenqing WEI ; Haipo CUI ; Jian CHEN ; Yunzhang CHENG ; Qianli CHENG
Journal of Medical Biomechanics 2020;35(2):E216-E222
Objective To study the influence of hollow screws with five kinds of spatial distributions on the fixation effect of femoral neck fracture. Methods Geometric models of femoral neck fracture with Pauwels type I, II and III were built by reverse engineering according to CT images of the femur. Based on the finite element analysis software ANSYS, the stress distributions of internal fixation, head side and stem side of femoral neck and the displacement distributions of the model fixed by different methods were obtained. Results For femoral neck fracture with Pauwels type I, II and III, the maximum stresses at head side of femoral neck were the inverted triangle fixation method, two-screw parallel fixation method, two-screw parallel fixation method, respectively. The maximum stresses at stem side of femoral neck were the inverted triangle fixation method, inverted triangle fixation method and two-screw parallel fixation method, respectively. The minimum stresses on the screws were the cross fixation method, and the minimum displacements of the model were double-supported fixation method. Conclusions The probability of screw deformation and fracture is the smallest for cross fixation method. Inverted triangle fixation method can provide a good mechanical environment for fracture site. For femoral neck fracture with Pauwels typeⅠ and Ⅲ, double-supported fixation method has the strongest ability to prevent femoral neck shortening. While for femoral neck fracture with Pauwels typeⅡ, cross fixation method has the strongest ability to prevent femoral neck shortening.
6.Sensitivity Analysis of Flow Diverter Treatment of Intracranial Aneurysm Using Porous Media Model
Bin BAI ; Yunzhang CHENG ; Hui GAO ; Nan LÜ ; Linjing PENG
Journal of Medical Biomechanics 2020;35(6):E718-E724
Objective To simulate the hemodynamic effects of different flow diverters (FD) parameters by using computational fluid dynamics (CFD) technology, so as to develop a more reasonable FD embolization strategy before operation. Methods The porous media model was used to simulate the process of FD implantation into aneurysms, and the initial values of its own unique porous media momentum source parameters (permeability and inertial resistance) were calculated for a specific FD (Tubridge).The changes of hemodynamic parameters such as blood flow velocity, wall shear stress (WSS), volume flow and pressure of aneurysm-roof were compared under different situations (initial values of 80%, 90%, 100%, 110% and 120%), and the sensitivity analysis on hemodynamic parameters of patient-specific intracranial aneurysms (IA) for the porous media model was further conducted. Results The sensitivity of IA hemodynamic parameters to the permeability of porous media model was as follows: WSSparent-artery>WSSaneurysm>paneurysmal-roof, but the sensitivity to inertia resistance was relatively lower. Conclusions By using the porous media model, different metal coverages (MC) of FD could be simulated by choosing different permeability parameters, so it is necessary to adjust specific permeability settings during modeling of FD with different MC.
7.Effects from Side Branch Diameter of Intracranial Aneurysm on Hemodynamic Parameters after Flow Diverter Implantation
Hui GAO ; Yunzhang CHENG ; Xiangkun LIU ; Bin BAI ; Linjing PENG
Journal of Medical Biomechanics 2020;35(4):E403-E409
Objective To comprehensively consider the effect of low diverter (FD) implantation on aneurysmal sac and its branches, so as to provide references for making a more reasonable surgical strategy for intracranial aneurysm embolization in clinical practice. Methods Based on computational fluid dynamics (CFD) method, the FD implantation procedure was simulated by using porous media model innovatively. Changes in hemodynamic parameters of aneurysmal sac and side branch with different diameters before and after FD implantation were compared and analyzed, such as blood flow field, velocity, wall pressure and wall shear stress (WSS). Results FD changed the hemodynamic characteristics of aneurysms. The blood flow velocity decreased significantly. The WSS on aneurysmal neck increased, while the difference of WSS between proximal and distal cervical area reduced conversely. Different side branch diameters of vessels had different effects on hemodynamic characteristic changes. The larger diameter would cause the greater blood flow reduction in side branch after FD implantation, but the decrease in velocity of aneurysmal sac and pressure on aneurysmal roof became smaller simultaneously. Meanwhile, the increase of WSS on aneurysmal neck was inversely proportional to the diameter of side branch. Conclusions The larger branch diameter of vessels would cause the worse effect of FD embolization therapy for intracranial aneurysm, worse atherosclerosis improvements and greater possibilities of branch occlusion or other ischemic complications. Doctors should pay more attention to such cases in FD interventional intravascular embolization in clinic.
8.Discussion on Strengthening Medical Supplies Management on Open Platform.
Yunyun CAI ; Chunyu MAO ; Haifeng GAO ; Peidi ZHU ; Jingjing GU ; Yunzhang CHENG
Chinese Journal of Medical Instrumentation 2020;44(3):276-279
We introduce the background of Shanghai medical purchasing service and supervision platform (later we call it "open platform") and the effect of its implementation. We also analyze the problems occurred by medical institutions in the management of supplies, explore how to use open platform to strengthen the management of medical supplies, further optimize the structure of supplies, standardize the clinical reasonable use and charges, and ensure the quality, safety and traceability of supplies.
China
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Equipment and Supplies
9.Detection and Rectification of Radiation Emission from Medical Laser Equipment.
Chinese Journal of Medical Instrumentation 2019;43(5):372-374
By introducing the unqualified cases of radiation emission test of medical laser equipment, this paper analyses the causes of the problems and the corrective measures adopted, and analyses the effectiveness of the corrective measures. It is proposed that the design rules and rules related to radiation emission should be mastered from the input stage of product design and development, and the radiation emission problem should be considered and solved as soon as possible.
Equipment Design
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Laser Therapy
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instrumentation
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Lasers
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Light
10.Characteristics of left atrial function real-time three plane strain rate imaging in patients with hypertension and coronary artery stenosis and their significances
Ye ZHOU ; Yunzhang CHENG ; Jingyuan HUANG
Journal of Jilin University(Medicine Edition) 2016;42(5):1019-1023
Objective:To investigate the characteristics of real-time three plane strain rate imaging of left atrial function in the patients with primary hypertension and coronary artery stenosis, and to evaluate its clinical application value.Methods:Total 82 patients with primary hypertension were selected and divided into primary hypertension group (EH group,n=42)and primary hypertension complicated with coronary artery stenosis group (EHCHD group,n=40).In addition,the physical examination people were selected as control group (n=42).All the subjects were examined by conventional echocardiography,and the left atrial function in real-time three plane strain rate imaging was analyzed.The parameters of conventional echocardiography and real-time three plane strain rate imaging were compared.Results:Compared with control group,the systolic left atrial mean peak strain rate (SRs),early diastolic left atrial mean peak strain rate (SRe)and SRe/SRa of the patients in EH group and EHCHD group were significantly decreased (P < 0.05);the atrial systolic mean peak strain rate (SRa)and Time-SRa in EH group and EHCHD group were significantly increased (P <0.05).Compared with EH group,SRs,SRe and SRe/SRa in EHCHD group were obviously decreased (P < 0.05 );SRa and Time-SRa were significantly increased (P <0.05).Conclusion:Real-time three plane strain rate imaging can easily and accurately analyze the left atrial function in the patients with essential hypertension and coronary artery stenosis,it is worth to popularize in clinical application.

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