10.3969/j.issn.1008-9691.2013.03.010

Objective To observe the therapeutic effect of integrated traditional Chinese and western medicine treatment on systemic inflammatory response syndrome after trauma. Methods Totally 86 cases of severe trauma patients with systemic inflammatory response syndrome in ICU were randomly divided into control group and treatment group. The control group was given routine treatment of ulinastatin, and the treatment group was treated with Xuebijing injection 50 mL, intravenously injected twice per day and rhubarb powder 10 g through stomach tube twice per day for 5 days. The clinical effect and levels of inflammatory factors before and after treatment of the two groups were observed. Results During 5 days of treatment, the levels of TNF-α, IL-6 and IL-8 of the treatment group decreased continuously (P<0.05), while which of the control group increased continuously (P<0.05). CRP level of the two groups had no significant difference in the first day of treatment (P>0.05), but which of the treatment group was lower than the control group from the second day of treatment (P<0.05). The average hospital stay, ICU stay, 28 d mortality and APACHEⅡ score of the treatment group were better than that of the control group (P<0.05). Conclusion Xuebijing injection and rhubarb powder in addition to conventional treatment can relieve inflammatory response, effectively inhibit the generation and release of inflammatory mediators, improve the survival rate of systemic inflammatory response syndrome.