1.Investigation of Mycoplasma pneumoniae infection in chilalren
Hairong JIN ; Mingfang MA ; Yunxiang CAI
Chinese Journal of Primary Medicine and Pharmacy 2011;18(2):159-160
Objective To investigate relationship between infection rate of Mycoplasma pneumoniae(MP) in children with corresponding gender, age and season. Methods Mycoplasma pneumoniae IgM (MP-IgM) antibody level in serum was measured utilizing method of passive particle agglutination. Results From 2007 to 2009, MP-IgM antibodies among total 1701 children with pneumoniae were detected in the study, of which 569 cases showed MP-IgM antibodies positive (569/1701,33.5%). The MP-IgM positive rate in male and female patients were 30.1% and 37. 8% respectively and the difference was statistically significant (P < 0. 01). The MP-IgM positive rates in 0 ~ 1year-old group,2 ~ 3 year-old group ,4 ~ 6 year-old group and 7 ~ 14 year-old group were 5.8% ,35.3% ,43.3% and 52.9%, respectively. The disparities of MP-IgM positive rate between the groups was statistically significant (P <0.01,P < 0.01 and P < 0.05, respectively). The differences of MP-IgM positive rates during the peroid of 2007,2008and 2009 were statistically significant(P < 0.01), but no difference was significantly exhibited during the peroid of 2008 verse 2009 (P > 0.05). As for onset distribution of season, in year 2007, MP infection rates between the individual seasons were not statistically different. Conclusion MP infection was mainly prevailed in those whose ages were over three years old. MP infection was inclined to occur in female children than in male and the prevalent season was the Spring.
2.Pathogenic Bacteria and Antimicrobial Resistance Analysis of Nosocomial Infections for 958 Diabetics in Hospital
Yunxiang ZENG ; Wenpin CAI ; Gaogui LIN ; Fangyou YU ; Youze HUANG
Chinese Journal of Nosocomiology 2006;0(09):-
50%).The resistance of Enterococcus avium and E.faecalis to ciprofloxacin was over 30%.CONCLUSIONS To Gram-negaive bacteria may use ?-lactamase inhibitors with antimicrobials and amikacin.To nonfermenters may use ciprofloxacin.To Gram-positive bacteria may use teicoplanin,nitrofurantoin,ampicillin/sulbactam and others.
3.Efficacy and safety of Solifenacin in the treatment of patients with urgency and urge incontinence WU
Shiliang WU ; Yunxiang XIAO ; Jihong DUAN ; Qiang DING ; Yinghao SUN ; Yiran HUANG ; Bo SONG ; Songliang CAI ; Yanqun NA
Chinese Journal of Urology 2009;30(9):630-634
eiving Solifenacin 5.8% compared to those recei-ving Tolterodine 10.4%(P<0.05). Conclusion Solifenacin could be the safer and effective drug in the treatment of OAB patients with main complaints of urinary urgency and urgy incontinence.
4.Study of MR diffusion tensor imaging to monitor the damage degree of optic nerve in non?arteritic anterior ischemic optic neuropathy
Pengde GUO ; Pengbo ZHAO ; Jing ZHAO ; Yan SU ; Ming LIU ; Yunxiang CHEN ; Weixin WANG ; Yan WANG ; Haiqin HUA ; Shaohong KANG ; Lingling CAI ; Ting ZHANG
Chinese Journal of Radiology 2018;52(10):761-765
Objective To study the feasibility and value of magnetic resonance diffusion tensor imaging (DTI) to monitor non?arteritic anterior ischemic optic neuropathy (NAION). Methods Thirty eight NAION patients (56 eyes) were divided into acute period in 17 eyes, progressive period in 16 eyes and chronic period in 23 eyes at the base of onset time. According to matching principle, 56 eyes in 38 normal controls (NCs) were enrolled. All the patients and NCs underwent MR and DTI scan. The raw data were processed by two experienced radiologists, mean diffusivity (MD), axial diffusivities (λ//), radial diffusivities (λ┴), fractional anisotropy (FA) and Length value were got. The independent sample t test was used for the parameter values between the NAION group and the NCs group. A single factor variance analysis was used to compare the parameters among different stages of NAION group. Results Compared to the NCs group, the values of FA and Length in NAION group were reduced [0.20±0.11 vs 0.31±0.12, (5.85±0.92) vs (65.11± 6.89) mm], and the differences were statistically significant (t=-4.28,-5.25;P<0.05). The values of MD andλ┴were increased [(0.16±0.04)×10-3 vs (0.10±0.04)×10-3 mm2/s, (0.16±0.05)×10-3 vs (0.09±0.03)×10-3 mm2/s] in NAION group and the differences were statistically significant (t=6.83, 7.10;P<0.05). The value of FA and Length in acute period, progressive period and chronic period of the NAION group decreased differently compared to the NCs group. At the same time, the value of MD value and λ┴in the three periods of the NAION group increased compared to the NCs groupand the differences were statistically significant (P<0.05). The value of FA between the acute period, the progressive period, and the chronic period of NAION group were statistically signficant (F=10.88, P<0.05). However, no significant differences were found in the values of MD, λ┴and Length of the NAION group (F=0.23, 0.64, 0.33, 1.38;P=0.79, 0.54, 0.72, 0.27). Conclusion The parameters of DTI can be used to monitor the damage of optic nerve and development in NAION.
5.Preservation of supraclavicular nerve in fixation of clavicular fracture
Xibin PAN ; Kuanhai WEI ; Longzhou GUAN ; Guoxiong CAI ; Bin CHEN ; Yunxiang ZHONG ; Shao-Quan HUANG ; Jian ZHANG ; Yanhua XIE
Chinese Journal of Orthopaedic Trauma 2020;22(4):351-355
Objective:To investigate the clinical significance of preserving supraclavicular nerve in the reduction and fixation of clavicular fracture.Methods:A retrospective study was conducted of the 68 pa-tients with clavicular fracture who had been treated surgically from October 2016 to April 2018 at Department of Orthopedics and Traumatology, Heyuan Hospital of Traditional Chinese Medicine.They were 35 males and 33 females, aged from 25 to 45 years (average, 34.8 years).The supraclavicular nerve was preserved in the re-duction and fixation of clavicular fracture in 32 patients (reservation group) but not in the other 36 ones (control group).The 2 groups were compared in terms of operation time, intraoperative blood loss, fracture healing time; postoperative pain tolerance, feeling (by the British Medical Research Council assessment), shoulder function (by the Constant-Murley scoring) and impact of numbness on life.Results:The 2 groups were compatible due to insignificant differences in the general clinical data between them ( P>0.05).All the 68 patients were followed up for 12 to 26 months (average, 15 months).There was no significant difference between the 2 groups either in intraoperative blood loss or fracture healing time ( P>0.05).The preservation group had significant longer operation time (72.6 min±7.2 min) than the control group (47.3 min±7.4 min), but a significantly lower rate of analgesic usage on the postoperative day [6.3%(2/32)] than the control group [91.7%(33/36)] (both P<0.05).By the British Medical Research Council assessment, the postoperative feeling was rated as S3 or S4 in 93.8%(30/32) of the patients in the preservation group, significantly higher than the 72.2% (26/36) of the control group ( P<0.05).The preservation group was also significantly better than the control group in Constant-Murley scores of the injured shoulder [100.0 (93.5, 100.0) versus 87.0 (81.0, 89.0)] and impact of numbness on life [0 versus 50.0%(18/36)] (both P<0.05). Conclusion:In surgical treatment of clavicular fracture, preservation of the supraclavicular nerve can have a positive effect on reducing postoperative pain in the operative area and impact of numbness on life.