No abstract available.
Humans ; Quality of Life* ; Self Care*

Excitatory Amino Acids ; secretion ; Humans ; Neurotransmitter Agents ; secretion ; Pain, Postoperative ; etiology ; metabolism ; prevention & control

Atherosclerosis ; Humans

Objective To explore the relationship of DNA damage and cell apoptosis in the blood vessel endothelial cell of diabetic rats. Methods Streptozotocin was used to make diabetic rats, 16 rats were random divided into diabetic group and control group. DNA damage was measured by comet assay and cell apoptosis was detected by flow eytometry. Results DNA damage score was 29.5 ± 6.7 and 8.6±3.6 in diabetic rats and controls, the rate of cell apoptosis was respectively 10.9±3.5 and 4.4 ± 1.2. It had a significant difference between two groups in DNA damage and cell apoptosis(P < 0.05). The rat of cell apoptosis had strongly positive correlation with DNA dam-age scores (r = 0.82, P < 0.05). Conclusion DNA damage and cell apoptosis are found in diabetes mellitus, cell apoptosis may be asso-ciated with DNA damage. The roles of DNA damage and cell apoptosis in diabetes mellitus need further research.

Primary airway tumors are accounted about 1 % of respiratory tumors and have above 20 types. However, due to particularity of the anatomy and function of airway, early diagnosis of the primary air tumors is difficult and the rate of misdiagnosis can reach 83.3 %. To reduce the rate of misdiagnosis, the key measurements of diagnosis are recognization of primary airway tumors, and the main methods include chest computed tomography (CT) and fiberoptic bronchoscopy examination. Surgical treatment is an important part,it includes tumor excision by airway fenestration, the part excision of airway and suture, the resection of airway tumor by its margin and anastomosis, and carinal resection and anastomosis. Anesthesia and the management of respiratory airway are important guarantees for the successful operation. According to the difference of the tumors, the suitable method of anesthesia should be choiced. It is emphasized for anesthesiologist to participate in the preoperative discussion. The postoperative complications include the anastomotic fistula, the anastomotic fistula communication with large vessel, the anastomotic stenosis and granuloma formation, and the pulmonary infection and atelectasis.

Objective To investigate the regularity and characteristic of adverse drug reaction (ADR).Method 987 ADR cases collected in our hospital from 2005 to2010 were analysed statistically.Results Numbers of ADR reports increased quickly.The incidence of new and severe ADR increased every year.Numbers of ADR reports written by nurses and pharmacists increased every year.The incidence of ADR in female was higher than in male.Antimicrobials showed the highest proportion (76.46％) among all kinds of drugs which were involved in these ADR cases.Among all antimicrobials,penicilins which advanced cephalosporins and quinolones showed the highest proportion.83.49％ which were largest were caused by intravenous administration.Main clinical manifestation were lesion of skin and its appendants (44.66％).Conclusion Publicity and training of ADR knowledge,ADR monitoring and rational drug use should be strengthened in order to use drug safely.

Severe mycoplasma pneumoniae pneumonia is indicated as severe clinical symptoms,long course of disease,many extrapulmonary complications and the response to conventional therapy is poor.Its incidence has been increasing day by day,the inefficiency of host resistance to m ycoplasma pneumoniae,disorders of immune response and pathogenic immune escape are suggested to play critical roles in the immune mechanism of severe mycoplasma pneumoniae pneumonia.This paper summarizes the progress of immunopathogenesis of severe pneumoiae pneumonia in children.

This article analyses the basic theory, form, features and purpose of the college spoken English testing to be carried out throughout the country, and probes the corresponding teaching method in order to improve college spoken English teaching.

Objective To analyze the situation of the intellectual development of children between 0 to 18months.Methods Using Denver Developmental Screening Test(DDST),1 064 children aged between 0 to 18 months in four items:their indicidual and social reaction ability,subject-touching reaction ability of fingers,and speaking ability as well as movement ability were tested,each itern had 2 kinds of tests and here only need to test one kind which is shown on the left part of DDST.Every example need to understand the pregnancy history,family history,birth of children,past history,parents'jobs and education level.The measured results were calculmed,about the ages of which 50%examlnation could pass in each test itern and 90%could pass,and compared with tested children in Denver.Results The passing rate of same item would be increased as age increases.the passing rate would be different between different test items in the sslne age,and the more difficult the item,the lower the passing rate.The common trend of children's intellectual development Was in accordance with that of Denver children,whereas there were age differences that pass certain items.Conclusion As a screening way of infants'intellectual tests,DDST had universal significance.Lacking scientific education was an important cause of mental retardation in children.

Aged ; Female ; Hemangioma, Cavernous ; complications ; Humans ; Kasabach-Merritt Syndrome ; complications ; Liver Neoplasms ; complications