1.Clinical observation of combined lensectomy with vitrectomy, retaining the peripheral anterior lens capsule
International Eye Science 2014;(9):1689-1690
To investigate the curative effect of retaining the peripheral anterior lens capsule combined lensectomy with vitrectomy for ocular trauma.
●METHODS: Totally 33 patients ( 33 eyes ) with eye trauma underwent combined lensectomy with vitrectomy, retaining the peripheral anterior lens capsule and phase Ⅱposterior chamber lOL implantation. After follow - up of 6mo, visual acuity, intraocular pressure ( lOP ), lOL position, and intraoperative and postoperative complications were observed.
●RESULTS: Visions of all the patients were improved at varying degrees. After follow-up of 6mo, no obvious lens deflected and serious complications ( glaucoma, retinal detachment) appeared.
●CONCLUSlON: Combined lensectomy with vitrectomy, retaining the peripheral anterior lens capsule for ocular trauma has good curative effects of lessening complications during operation and postoperation and good visual acuity recovery.
2.Advances in the Treatment of Multiple myeloma
Journal of Kunming Medical University 2016;37(10):1-4
Multiple myeloma is a monoclonal plasma cell malignant proliferative disease,accounting for about 10% of malignaut tumors of blood system.In recent years,due to the application of hematopoietic stem cell transplantation and the application of MDT by combining new drug such as thalidomide,lenalidomide and bortezomib,the average survival of MM patients was significantly longer than before.The treatment strategy should be individualized before treatment according to the patient's age,physical condition and complications.In this paper,the treatment strategy of multiple myeloma patients were reviewed.
3.Inflammatory myofibroblastic tumors in dura mater of brain: one case report.
Hong ZENG ; Hai-gang LI ; Yun-jie ZENG
Chinese Journal of Pathology 2006;35(4):254-255
Actins
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metabolism
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Adult
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Brain Neoplasms
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metabolism
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pathology
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surgery
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Desmin
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metabolism
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Diagnosis, Differential
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Dura Mater
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chemistry
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pathology
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Female
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Granuloma, Plasma Cell
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metabolism
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pathology
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surgery
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Humans
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Immunohistochemistry
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Meningeal Neoplasms
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pathology
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Meningioma
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pathology
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Neoplasms, Muscle Tissue
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metabolism
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pathology
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surgery
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Vimentin
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metabolism
4.Relationship between polymorphism of FcγRIIIA F158V genotype andsystemic lupus erythermatosus as well as lupus nephritis in Chinese Han population
Yun ZHANG ; Shufen LIU ; Xuejun ZENG
Basic & Clinical Medicine 2017;37(5):709-713
Objective To find the frequencies of FcγRIIIA polymorphisms in Chinese people and the potential role of these polymorphisms(SNPs) in systemic lupus erythermatosus(SLE) and lupus nephritis(LN).Methods The investigation covers 324 unrelated Chinese SLE patients and 319 controls.FcγRIIIA F158V polymorphism was genotyped by specific primer-polymerase chain reaction(PCR).Results The frequency of F allele of FcγRIIIA polymorphism is 60.8% in Chinese people.FcγRIIIA polymorphism revealed a significant difference of both genotype and allele distribution in SLE patients and controls.LN patients have a significant increase in carrier frequency of the FF genotype, while the VV genotype reveals a significant decreased risk of early onset of LN.ConclusionsFcγRIIIA polymorphisms is potentially related with SLE in Chinese people.The homozygous FF genotype of FcγRIIIA might be the risk factor for LN, while the homozygous VV genotype might be the protective factor for late onset lupus nephritis.
5.Inhibitory Effect of Chinese Herbal Compound Dongju on Tongue Carcinogenesis in Rats
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(10):-
Objective To examine the inhibitory effect of Chinese herbal Compound Dongju on 4-nitroquinoline 1-oxide(4NQO)-induced tongue carcinogenesis in rats. Methods A total of 85 Wistar rats were divided into four groups: model group(n=35),administration group(n=35),normal control group(n=5) and herb control group(n=10).4NQO dissolved in drinking water was administered orally to induce tongue carcinogenesis in rats.The herb compound was injected into the stomach of the rats during oral carcinogenesis.Rats were sacrificed at 9,13,20,24 and 32 weeks from the beginning of the experiment.The tongues of the rats were dissected for gross and histological assessment,and SP immunohistochemical method was also employed to detect the expression of cyclin D1 in the specimens. Results Compared with the model group,the incidence of dysplasia and the positive rate of cyclin D1 were suppressed by Compound Dongju(P
6.Treatment of acute retinal necrosis syndrome
International Eye Science 2015;(5):813-816
?Acute retinal necrosis syndrome ( ARN) is a serious eye disease, which caused by Herpes virus mostly, with unknown pathogenesis. Because of the aggressive progression, treatment of ARN is difficult, and the blindness rate is extremely high. Current treatment strategies are the combination of the drug therapy and the operative treatment. Drugs commonly used are antiviral drugs, glucocorticoids, and antiplatelet drugs, and the operative treatment includes laser photocoagulation and vitrectomy.
7.Changes of growth hormone,brain natriuretic peptide and adrenomedullin in congestive heart failure
Yun ZENG ; Jianzhong DING ; Hongyu ZHOU
Chinese Journal of Primary Medicine and Pharmacy 2009;16(7):1188-1189
Objective To evaluate the changes of growth hormone(GH), brain natriuretic peptide(BNP) and adrenomedullin(ADM) in congestive heart failure patients. Methods The blood samples were obtained from 60 pa-tients with congestive heart failure(CHF) and 30 patients without CHF,and their serum/plasma levels of GH,BNP and ADM were measured by enzyme-labeled immunosorbentassay(ELISA) and radioimmunoassay. At the same time all the patients received colorful Doppler ultrasonocardio-gram to determine left ventricular end-dilation diameter (LVED) and left ventrieular ejection fraction(LVEF). Results The levels of BNP and GH in heart failure group were[(0.83±1.06) μg/L,(115.31±191.16) ng/L] higher than eontrol group[(0.15±0.42) μg/L, (33.51±49.85) ng/L] (t = 2.689, t = 2.765, P < 0.01); The efficiency and total efficiency in heart failure group was (39.7% ,76.5%) higher than control group (32.3%, 61.3%) (t = 1.894, P > 0.05, t = 2.265, P < 0.05); The sensitivities and specificities of BNP were 89.3% and 63.0%; The sensitivities and specificities of GH were 85.7% and 59.3%; The BNP combined with GH were 75.0% and 74.0%. Condusion The combination of GH and BNP is better than application alone in the diagnosis of CHF.
8.Trends in Fluorescence Probe of Deoxyribonucleic Acid
Liansheng LING ; Zhike HE ; Yun ZENG
Chinese Journal of Analytical Chemistry 2001;29(6):721-724
This paper reviews the binding mode beween deoxyribonucle ic acid (DNA) and the different type of fluorescence probe. The application of t hese probes in DNA quantitation analysis and other ways is also reported. The pr ogress of DNA fluorescence probe is addressed.
9.Hyponatremia induced by iodipamide: three cases report.
He HUANG ; Jian-ping ZENG ; Yun LONG
Chinese Journal of Cardiology 2009;37(7):621-621