Atherosclerosis ; Humans

Excitatory Amino Acids ; secretion ; Humans ; Neurotransmitter Agents ; secretion ; Pain, Postoperative ; etiology ; metabolism ; prevention & control

No abstract available.
Humans ; Quality of Life* ; Self Care*

Breast Neoplasms ; etiology ; genetics ; pathology ; Chromosome Aberrations ; Comparative Genomic Hybridization ; Epithelial Cells ; pathology ; Female ; Fibroadenoma ; genetics ; Humans ; Loss of Heterozygosity ; Phyllodes Tumor ; etiology ; genetics ; pathology ; Stromal Cells ; pathology

This article analyses the chemical test results of several common repair mesh, and concludes the currently several common repair mesh are safe and reliable.
Prostheses and Implants ; Surgical Mesh ; standards

Aged ; Female ; Hemangioma, Cavernous ; complications ; Humans ; Kasabach-Merritt Syndrome ; complications ; Liver Neoplasms ; complications

Objective] Through the system arrangement of Fuxie theory on academic context and diagnosis and treatment,preliminarily discuss the relationship between the human papilloma virus infection and Fuxie,in order to more thoroughly understand the HPV infection,broaden the clinical diagnosis and treatment,improve the clinical curative effect.[Method] To analyze,arrange,summarize and conclude Fuxie theory from the concept,causes, pathways and treatment,that of famous ancient physicians. [Result] Fuxie theory originates from internal classic,then develop up to now.Although controversy persists in the process of development,Fuxie theory still has its important practical significance.Dictionary of Chinese Traditional Medicine defines Fuxie as disease hidden in the body without immediate onset.Not merely six exogenous factors and internal injuries,complex pathogens all can lead to evil lurking.For its pathological basis,outbound pathways should be based on syndrome,and identified according to the etiology.Strengthening the body resistance to eliminate pathogenic factors is the generally treatment of Fuxie, and treatment should be dialectical according to its pathogenesis. [Conclusion] By carding Fuxie theory and analyzing the relationship between HPV infection and Fuxie,fully confirm that“the human papilloma virus infection is Fuxie”. Fuxie perspective provides the basis for HPV infection treatment,and a new way of thinking for clinical prevention and control of HPV infection.

Objective To research the treatment of cervical HR-HPV infection by vaginal douching with eight kinds of antiviral herbs such as Radix Arnebiae and patrinia.Methods 42 patients with 13 types of cervical HR-HPV infection were selected from Outpatient.27 patients were recruited into a treatment group and 15 patients were recruited into a control group voluntarily.The treatment group was applied with antiviral herbs and the control group was applied with policresulen vaginal suppositories for 3 courses (one course for 7 days per month).The clearance rate and loading dose of 13 types of cervical HR-HPV were observed.Results The negative conversion ratio of the treatment group and the control group was 88.5％ and 15.4％ respectively,and the total efficiency was 100％ and 46.2％ in the treatment group and the control group respectively.The total efficiency between the two groups were significantly different(x2=17.062,P＜0.01).Conclusion The therapeutic effect of antiviral herbs for cervical HR-HPV infection was definite and with no side reactions.

Objective To analyze the situation of the intellectual development of children between 0 to 18months.Methods Using Denver Developmental Screening Test(DDST),1 064 children aged between 0 to 18 months in four items:their indicidual and social reaction ability,subject-touching reaction ability of fingers,and speaking ability as well as movement ability were tested,each itern had 2 kinds of tests and here only need to test one kind which is shown on the left part of DDST.Every example need to understand the pregnancy history,family history,birth of children,past history,parents'jobs and education level.The measured results were calculmed,about the ages of which 50%examlnation could pass in each test itern and 90%could pass,and compared with tested children in Denver.Results The passing rate of same item would be increased as age increases.the passing rate would be different between different test items in the sslne age,and the more difficult the item,the lower the passing rate.The common trend of children's intellectual development Was in accordance with that of Denver children,whereas there were age differences that pass certain items.Conclusion As a screening way of infants'intellectual tests,DDST had universal significance.Lacking scientific education was an important cause of mental retardation in children.

Objective:To observe the anti-tumor effect of T lymphocytes harboring anti-CD20 scFv-CD8-TCR? fusion gene on human B lymphomas in vitro and in vivo,so as to explore the feasibility of CD20-mediated autogenous T lymphocytes in killing B-cell lymphomas.Methods: A fusion gene containing anti-CD20 scFv,CD8 molecule and CD3? chain was constructed and was cloned into pcDNA3.After confirmed by restriction endonuclease analysis,the fusion gene was used to transfect the human peripheral T lymphocytes through electroporation and expression of anti-CD20 scFv-CD8-TCR? fusion protein was induced.The CD20 antigen-recognition ability of transfected T cells was determined by flow cytometry.The killing effect of transfected T cells on B cell lymphomas-Raji cells was tested in a cytotoxicity assay.The antitumor efficacy of this gene-modified T cell against the Raji tumor cell line was also evaluated in BALB/c nude mice.Results: We successfully constructed the anti-CD20 scFv-CD8-TCR? fusion gene and expressed its protein on T cells.Flow cytometry and cytotoxicity assay demonstrated that the gene engineered T cells specifically recognized CD20 antigen and specifically inhibited B-cell lymphomas Raji cells.Furthermore,the T cells significantly inhibited the transplanted Raji cells in irradiated BALB/c nude mice.Conclusion: T lymphocytes transfected with anti-CD20 scFv-CD8-TCR? fusion gene have antigen-specific anti-tumor effect in vitro and in vivo,which lays a foundation for utilizing human T lymphocytes to treat human B-cell lymphomas.