1.A case of lung cancer who received intrathecal catheter implantation to relieve intractable cancer pain and opioid-induced delirium
Toshiyuki Kuriyama ; Eiko Ueyama ; Yumi Nukui ; Mari Nakamura ; Shinobu Ishidoshiro ; Yoshi Tsukiyama ; Koichi Nishikawa
Palliative Care Research 2012;7(2):585-590
Introduction: We described a patient with lung cancer who suffered from severe pain due to pelvic bone metastasis and opioid-induced delirium. Induction of subarachnoid analgesia using implanted intrathecal catheter almost abolished his pain and enable home palliative care. Case description: Seventy-year old man was admitted for intractable leg and hip pain due to pelvic bone metastasis and delirium induced by opioid. Although he was initially administered continuous subcutaneous morphine injection for opioid titration, delirium was deteriorated. Opioid rotation to oxycodone and increase in antipsychotic drugs could not improve his delirium. Epidural analgesia with local anesthetic and small dose of morphine improve his delirium with adequate analgesic effect. Finally, he was received intrathecal catheter implantation and discharged to home palliative care. Conclusion: Neuraxial analgesia may provide not only sufficient analgesia but also lower risk of delirium in patient who was administered high dose of opioids because of intractable cancer pain.
2.Pilot Study on Intervention in Breast Cancer Patients with Loving-Kindness and Mindfulness Meditation
Shinobu YAMADA ; Yumi NUKUI ; Sayo NAKAMOTO ; Momoko BUYO
Japanese Journal of Complementary and Alternative Medicine 2022;19(2):87-96
Objective: In this practical study, mindfulness-based “Loving-Kindness and Mindfulness Meditation” was carried out for breast cancer patients. Methods: 60-minute meditation sessions were carried out every two weeks for a total of four sessions. At Month 1 and in the period up to Month 3 after intervention, changes in quality of life (QOL) were assessed using SF-36 v2 for a total of five times. Participants were taught to practice meditation at home, and their daily meditation experiences were written down as records. Results: Participants were divided into two groups, with two subjects in the intervention group and one subject in the non-intervention group. RCS based on SF-36 v2 were in the intervention group, and could be maintained or improved even one month after completion of intervention compared to before intervention. The records were divided into “Introduction phase” (for meditation in the first intervention); “Acquisition phase” (in and after the second); “Stable phase” (in and after the third); and “Establishment phase” (in and after the fourth). Correspondence analysis was performed for the fourth term by Text Mining. Conclusion: During early intervention at the “Introduction phase,” intentional concentration on what is occurring is carried out. As meditations continue, a change in the sense of self-consciousness, which cannot be experienced in daily life, is thought to occur.