Objective To explore the significance of P-selectin expressed in circulating blood in patients with pregnancy induced hypertension(PIH).Methods The expression of P-selectin were detected by flow cytometry in 30 PIH patients,20 normal pregnant patients and 15 normal controls.Results The level of P-selectin in PIH patients(18.63?8.92)% was significantly higher than that of normal pregnant group(3.25?1.73)%(P

Objective To investigate the mechanical properties and distributing characteristics of human fresh ulnar compact and its correlation to strain rate.Methods Impact compressive experiment for human fresh ulnar compact bone at high strain rate =1.2?10~(3)/s by Split Hopkinson Pressure Bars(SHPB) were performed.Results The mechanical properties of human fresh ulnar compact bone varied along the longitudinal direction,the ultimate stress,breaking strain and dynamic compressive modulus at middle section were stronger than those at both ends,the strongest at section occurs nearly at the junction of proximal and middle thirds and the properties at the proximal end were much higher than those at the distal end.The ultimate stress at high strain rate was largely dependent on strain rate.Conclusion Under impact compression,the ulnar compact gets fractured easily at both ends,especially at distance section.

Objective To understand the incidence and related risk factors of healthcare-associated infection(HAI)in neu-rological patients with cerebrovascular diseases.Methods The occurrence and risk factors of HAI in patients with cerebro-vascular diseases in a hospital between Jan and December 2013 were investigated and analyzed.Results Of 3 573 investiga-ted patients,214 had HAI,the incidence of HAI was 5.99%;the main infection site was respiratory tract (54.67%),fol-lowed by urinary tract (25.23%).Univariate analysis revealed that age,length of hospitalization,disturbance of conscious-ness,chronic obstructive pulmonary disease,diabetes mellitus,invasive procedures,application of antacids,and antimicro-bial prophylaxis were all related to the occurrence of HAI (P<0.05).Multivariate logistic regression analysis revealed that disturbance of consciousness,old age,invasive procedures,chronic obstructive pulmonary disease,and diabetes mellitus were independent risk factors for the occurrence of HAI (all P <0.05).Conclusion The incidence of HAI is high in hospitalized patients of the neurology department,there are multiple risk factors associated with HAI,it is necessary to take corresponding interventions for reducing the incidence of HAI.

Aim To establish an animal model of inflammatory pleural adhesion and to investigate the role of low-molecular-weight heparin(LMWH) in preventing encapsulation of pleural effusion.Methods Thirty New-Zealand rabbits were randomly divided into three groups:the model and the treatment group received injection of tetracycline(35 mg?kg~(-1)) in the right chest cavity,the control animals received injection of normal saline.LMWH (55 U?kg~(-1)) was injected into the right chest cavity of rabbits in the treatment group.The animals were killed on 14 d.Result In the model group,pleural effusion appeared at 2 h and reached maximum within 2～3 days.In the effusion,leukocytes accumulated and procoagulant activity increased at the same time.Fibrosis and pleural adhesion,encapsulation appeared on the fourteenth day.In the treatment group pleural effusion and procoagulant activity were reduced.No pleural adhesion was observed.Conclusion Tetracycline was successfully used to establish an animal model of pleural adhesion in rabbits.LMWH was effective in reducing pleural effusion and preventing pleural fibrosis and encapsulation.

Objective To study the efficacy and psychological intervention of budesonide combined with terbutaline inhalation in the treatment of children with asthma. Methods 100 children with asthma in our hospital from March 2015 to October 2016 were selected as the subjects. They were randomly divided into two groups: the control group and the experimental group, with 50 cases in each group. The control group received routine treatment of bronchial asthma, and the experimental group received budesonide combined terbutaline aerosol inhalation treatment, and psychological intervention, pay attention to the patient's psychological state. The clinical efficacy, relative clinical symptoms, improvement time and length of hospital stay were compared between the 2 groups. Results The effective rate of the treatment group was 94%, which was significantly higher than that of the control group (72%), and the difference was statistically significant (P<0.05). The improvement time of dyspnea, wheezing and cough in control group was significantly higher than that in experimental group, while the control group was significantly longer than the experimental group, the difference was statistically significant (P<0.05). Conclusion Compared with conventional treatment,budesonide combined with terbutaline aerosol inhalation and psychological intervention in the treatment of children with asthma has better clinical efficacy and shorter clinical symptoms. It has the significance of further popularization and application.

Objective To analyze the changes of the quality of life of patients with advanced lung cancer accompanied with dyspnea before and af?ter methylprednisolone therapy,so as to investigate the effects of methylprednisolone on the quality of life of the patients. Methods Totally 134 ad?vanced lung cancer patients with dyspnea were divided into two groups,the methylprednisolone group and the control group,according to whether they consented to the use of hormone therapy. All of them were followed with visual analog scale(VAS),the quality of life questionnaire?core 30 (EORTC QLQ?C30)and the quality of life questionnaire?lung cancer module 13(QLQ?LC13)questionnaire. Results At one hour after treatment compared to before treatment,the VAS scores for both groups were significantly decreased(P<0.01),and the score for the methylprednisolone group were lower than the control group(P<0.05). At two weeks after treatment compared to before treatment,social function,emotional function, and overall quality of life scores for both groups were decreased(P<0.05). But the scores of pain,dyspnea,insomnia,loss of appetite,constipation, dysphagia were increased(P<0.05). Compared to the methylprednisolone group,the dyspnea and pain score for the control group was higher(P<0.05). Conclusion Methylprednisolone may improve the quality of life of advanced lung cancer patients with dyspnea in short term and slow down the deteriorating process of their quality of life.

ObjectiveTo describe utilizations of maternal health care in migrant maternity in Putuo District and to identify the gap between primipara and multipara.In order to improve utilizations of Maternal Health Care in migrant maternity.MethodsQuestionnaire survey was carried out among lying-in migrant maternity to obtain information on utilization of maternal health care.Database was established the by Epidata 2.1 and Statistical analyzed by SPSS11.0.ResultsThere was significant difference between multipara and primipara in age,household registration and cultural degree(P＜0.01 ).Women registered at early stage of the pregnancy with 50.51％,completed full pre-natal health check-up with 82.83％,received postnatal visits with 78.45％ in migrant maternity.There was significant difference between multipara and primipara in registered at early stage of the pregnancy,full pre-natal health check-up,received the postpartuu visit,registered at first level hospital and the medical insurance coverage in migrant maternity(P＜0.01 ).ConclusionsThe levels of utilizations of maternal health care in migrant maternity in putuo district are significantly lower than local maternity,the levels of utilizations of maternal health care in multipara are lower than primipara in Putuo district.Improve utilizations of maternal health care in multipara and enhance utilizations of maternal health care in migrant maternity in Putuo district.

Objective To explore the clinical effects of treating acute radioactive stomatitis with Xiufu Decoction by mouth-washing and oral-taking. Methods All 108 cancer patients were recruited into a treatment group (n=56) and a control group (n=52). The treatment group was treated with Xiufu Decoction for 15 days, and the control group was treated with Nystatin tabletsfor 15 days, 3 times/day. Results There was significant difference between the two groups in odynolysis time, the control of mycotic stomatitis, life condition, and overall effects (P<0.01 or P<0.05). All patients in the treatment group completed the whole course of radiotherapy; while 5 patients in the control group suspended the radiotherapy due to serious mouth ulcer. Conclusion Xiufu Decoction has the functions of enhancing immunity, fixing wound surface, relieving pain, improving diet and sleep, raising life quality, and safeguarding the process of radiation therapy, besides the decoction is safe and without toxic effect.

Objective To probe into urban residents' mental health knowledge awareness in Jingmen city. Methods By means of self-compiled questionnaires, 563 community residents were surveyed about their mental health knowledge and access to it. Results For mental health- care knowledge, community residents scored a total of (42.52±8.79), among which, (15.34±3.25) points for relevant causes,(12.23±4.89) points for corresponding symptoms, and (14.92±4.26) for health behavior. Such aspects would affect a resident's awareness of mental health knowledge as the resident's education background,marriage and chronic diseases. Radio and television (48.3%), newspapers and magazines (41.4%), hospital expert advice (39.8%), and community medical services (36.1% ) were considered the better access to mental health knowledge. Conclusions Residents had considerably inadequate knowledge of mental health. Therefore, a variety of health- care education activities should be carried out to improve residents'mental health knowledge.

Objective To explore the value of adenosine deaminase (ADA),interferon (IFN)-γand soluble interleukin-2 receptor (sIL-2R) in differential diagnosis of tuberculous and malignant pleural effusion.Method The ADA activity,IFN-γ and sIL-2R levels of 48 patients with tuberculous pleural effusions and 32 patients with malignant pleural effusion were measured by colorimetry and ELISA respectively.Results The ADA activity,IFN-γand sIL-2R level in tuberculous pleural effusion was higher than that in malignant pleural effusion (P < 0.05).According to the receiver operator characteristic (ROC) curve,when 45 U/L was regarded as critical value of ADA,the sensitivity,specificity and accuracy of ADA in diagnosing tuberculous pleural effusion was 82%,91% and 86% ; when 100 ng/L was regarded as critical value of IFN-7,it was 85%,94% and 89%; when 450 μg/L was regarded as critical value of sIL-2R,it was84%,81% and 83%.When combined detection of three targets was done.it was 88%,100% and 94%.Conclusion The combined detection of ADA,IFN-γand sIL-2R can improve sensitivity,specificity and accuracy in diagnosing tuberculous pleurisy.