Objective To investigate the incidence of surgical site infection(SSI)following clean incision breast surgery under non-local anesthesia,and evaluate risk factors for SSI.Methods Clinical data of 3 327 patients who underwent clean incision breast surgery under non-local anesthesia in 22 hospitals in Fujian Province were surveyed retrospectively,SSI and risk factors were analyzed.Results Among 3 327 patients,1 502(45.19%)were with malignant tumors,the average dura-tion of surgery were (101.18 ±8.04)minutes;a total of 24 cases of SSI occurred,incidence of SSI was 0.72%;253 (7.60%)patients received pre-operative antimicrobial prophylaxis,62.66% used antimicrobial agents within 0.5-2 hours before surgery.The main pathogenic bacteria was Staphylococcus aureus .Univariate and logistic regression analysis re-vealed that malignant tumor,diabetes mellitus,and use of immunosuppressants were all risk factors for SSI (all P <0.05). Conclusion SSI following clean incision breast surgery under non-local anesthesia is well controlled,risk factors for SSI should be evaluated before operation,comprehensive preventive measures should be taken to reduce the incidence of SSI.

OBJECTIVE To understand the status of nosocomial infection(NI) and antibiotic use in various scale hospitals,and provide the evidence for targeted monitoring.METHODS All inpatients were requested to make a prevalence survey of NI and antibiotic use in 63 hospitals by bed-visiting and patients′ medical records checking.RESULTS Of the 34 840 patients investigated in 63 hospitals,the NI rate was 3.7%.The most common NI site was lower respiratory tract.The general ICU had the highest NI rate(35.5%).Gram-negative bacilli were the major pathogens in NI,the most common pathogen was Pseudomonas aeruginosa.The fungi accounted for 18.6%.CONCLUSIONS To effectively prevent and control NI,it should take some measures,such as enhancing the doctors′ diagnostic level of the NI,reducing the rate of NI misdiagnosis,monitoring the departments with the high NI rate,strengthening the rational antibiotic usage,and raising the pathogen detection rate.