1.Application of disease screening with magnetically controlled capsule endoscopy
Yulan GAO ; Xiaoqian WU ; Leilei GUO ; Qian NIE
China Journal of Endoscopy 2017;23(7):60-65
Objective To study the clinical value of magnetically controlled capsule endoscopy in diseases screening. Method We retrospectively analyzed 61 cases which were evaluated by magnetically controlled capsule endoscopy from March 2015 to December 2016. The items include operating time, the divergence rate score and cleanliness score of stomach. The consistency was compared between magnetically controlled capsule endoscopy and gastric duodenal endoscopy. Results 61 upper gastrointestinal tract studies were included. The mean age was (49.4 ± 11.6) years. No capsule retention, perforation or bleeding occurred. There was 98.4% patients, which cleanliness of stomach was good. There was 68.9% patients, which filling degree of stomach was good. The concordance rate of the two tests of gastrduodenoscopy and magnetically controlled capsule endoscopy was 89.9% (80/89). The concordance rate of the two tests was 78.9% (15/19) in esophageal and cardia, 92.9% (52/56) in stomach, 92.9% (13/14) in duodenum. Conclusion Our experience shows that magnetically controlled capsule endoscopy is a safe and useful tool for the diagnosis of upper gastrointestinal tract disease. The detection rate is similar to gastrduodenoscopy.
2.Medical Waste Management at Public Region of Outpatient Service: Difficulty Point and Countermeasure
Suqiu LIU ; Yulan NIE ; Yongyi HAN ; Wenli XU
Chinese Journal of Nosocomiology 2006;0(05):-
OBJECTIVE To investigate the difficult point about the medical waste management at public region of outpatient service and to improve it.METHODS The form of questionnaire self-designed by the hospital about the medical waste related knowledge knowing rate among outpatients,the propaganda of medical waste related(knowledge) and the setting of special-purpose container for medical waste,was surveyed among 200 outpatients and 20 outpatient service medical personnel.RESULTS The medical waste related knowledge knowing rate was below 10% among outpatients,the medical waste related knowledge received ownself and from medical personnel was 13% and 2.5%,respectively.More than 35% of the medical personnel and 56% outpatients thought the setting of special-purpose container for medical waste was unreasonable.(CONCLUSIONS) The propaganda of medical waste related knowledge must strengthen,and the medical waste related knowledge knowing rate among outpatients must be higher.The improvement medical waste(special)-purpose facility at the public region of(outpatient) service is an important link for standardized management of medical waste.
3.System Intervention for Improving Grass Root Medical Staff Protection Against Occupational Infection
Suqiu LIU ; Zili ZHU ; Yuchi ZHAO ; Yulan NIE ; Yunsheng WU
Chinese Journal of Nosocomiology 2006;0(06):-
OBJECTIVE To discuss the efficiency method of improving consciousness and action for occupational infection protection among grass root medical staff.METHODS To conduct multiform health education,found restrict system,inspect and supervise,optimize protection flow,consummate protection establishment,and strengthen important link management in key departments in order to realize the system intervention among grass root medical staff.RESULTS Due to the system intervenion,the understanding rate of occupational infection protection knowledge improved from 48% to 96%,the average rate of occupational infection protection improved from 56.6% to 97.7% with significant differences(P
4.Reproductive health status and its influencing factors among out of campus girls
Siwei SUN ; Yinghua LI ; Xueqiong NIE ; Yulan CHENG ; Wei WEI ; Nanfang WEI ; Baohua LIU
Chinese Journal of Health Management 2013;(3):151-154
Objective To study the epidemiological status of reproductive health related behaviors of out of school adolescents in Kunming and Shenzhen City,and to explore the social-psychological influencing factors of the behaviors.Methods A cross-sectional study was conducted in 410 out of school adolescents aged 15-24 years who were recruited with accidental sampling.All the subjects were required to complete a self-administrated questionnaire.Single factor Chi-square analysis and multi-factor Logistic method were used for data analysis.Results The correct respondent rate of the questions on reproductive health knowledge among the adolescents was low.The sexual intercourse rate was 42.9% (176/410).Nearly 44.9% (79/176) of the adolescents who had sexual experience did not use condom in the latest sexual intercourse,and those who had no less than one sexual partner accounted for 48.9% (86/176).The prevalence of genital discomfort and sexual transmitted disease was 48.8% (200/410) and 2.9% (12/ 410),respectively.Chi-square test showed that marriage,living statue,behaviors of holding hands,kiss,caress the body,sexual intercourse and having no less than one sexual partner influenced the prevalence of genital discomfort(x2 values were 4.667,10.862,10.032,15.619,17.423,28.239,17.817 and 21.369,respectively ; all P < 0.05).In binary Logistic analysis,living in a dormitory or with other people,behaviors of caress the body,sexual intercourse and having no less than one sexual partner influenced the prevalence of genital discomfort (odds ratio (OR) was 0.449 (95% CI:0.216-0.933),0.377 (95% CI:0.147-0.967),4.364 (95% CI:1.594-11.949),0.312 (95% CI:0.111-0.877) and2.646 (95% CI:1.417-4.941),respectively ; all P < 0.05).Conclusions The status of reproductive health was poor among out of school girls in kunming and Shenzhen,and living status,behaviors of caress the body,sexual intercourse and having no less than one sexual partner could influence the prevalence of genital discomfort.Comprehensive measures should be taken to strengthen the reproductive health management in this population.
6.Curative effect of homemade "Sanhuang powder" in the treatment of genital human papilloma virus (HPV) infection
China Modern Doctor 2015;(21):101-103
Objective To study the exact clinical efficiency of "Sanhuang powder" in treatment of human papillo-mavirus (HPV) infection. Methods The 160 patients suffered from cervicitis with HPV infection persisted from January 2012 to January 2015 at Nanhai District Maternity and Child Healthcare Hospital were selected and randomly divided into treatment group and control group. The treatment group included 81 patients were given "sanhuang powder". The control group included 79 patients were given Recombinant human interferon α-2b suppository. The medication were given 2 weeks after menstruation, and continued treatment for 3 months, all the patients came back to accept gyneco-logical examination one month after stoping medicine, TCT and HPV-DNA test and electronic vaginal examination be-fore and after treatment were observed and analyzed respectively. Results The effect of HPV of two groups had no sig-nificant difference(P>0.05). Conclusion"Sanhuang powder"has anti-HPV infection and exact clinical efficiency, is suit able for clinical application.
7.Application of immune inflammatory markers combined with magnetic controlled capsule internal examina-tion in the diagnosis of gastric adenocarcinoma and precancerous lesions
Xiaoqian WU ; Xuexin LIU ; Yulan GAO ; Zhihua HAO ; Leilei GUO ; Qian NIE
The Journal of Practical Medicine 2024;40(16):2333-2339
Objective To investigate the potential of immune-inflammatory markers and the characteristics of magnetically controlled capsule endoscopy in distinguishing gastric adenocarcinoma from precancerous lesions,as well as to develop and validate a risk prediction model.Methods Retrospective analysis was conducted on medical records of 578 patients who underwent magnetic controlled capsule endoscopy at our hospital between January 2021 and December 2023.Following the principle of Pareto's law(80/20 rule),they were randomly divided into a training set(462 cases)and a validation set(116 cases).Magnetic controlled capsule endoscopy and blood cell tests were performed,with pathological diagnosis results serving as the"gold standard",to classify patients into groups of gastric adenocarcinoma and precancerous lesions.The magnetic controlled capsule endoscopic features,neutrophil-lymphocyte ratio(NLR),platelet-lymphocyte ratio(PLR)in patients with gastric adenocarcinoma and precancerous lesions were compared to develop and validate a risk diagnostic model for gastric adenocarcinoma.Results Among the 462 patients who underwent magnetic controlled capsule endoscopy,gastric adenocarcinoma was diagnosed in 76 cases through pathological examination,accounting for 16.45%(76/462),while precancerous lesions were observed in 386 cases,accounting for 83.55%(386/462).In the validation set of 116 patients who underwent gastric endoscopy,there were 22 cases of gastric adenocarcinoma,representing an incidence rate of 18.97%(22/116),and a total of 94 cases with precancerous lesions,accounting for an incidence rate of 81.03%(94/116).No statistically significant differences(P>0.05)were found between the two groups regarding lesion size,border appearance,mucus presence or lesion morphology.However,compared to the precancerous lesion group,the proportion of whitish coloration as well as irregular surface microstructure and grid-like microvessels was significantly higher in the gastric adenocarcinoma group(P<0.05).Moreover,both NLR and PLR values were significantly higher in the gastric adenocarcinoma group compared to those in the precancerous lesion group(P<0.05).Irregular surface microstructure(OR=2.213,95%CI:1.288~3.801),irregular grid-like microvessels(OR=2.489,95%CI:1.458~4.249),NLR(OR=2.369,95%CI:1.389~4.046),and PLR(OR=3.016,95%CI:1.767~5.148)were identified as risk factors for gastric adenocarcinoma(P<0.05).The sensitivity of the risk model for diagnosing gastric adenocarci-noma in the training set was 0.800(95%CI:0.716~0.891),with a specificity of 0.783(95%CI:0.694~0.851)and an area under the curve of 0.858(95%CI:0.787~0.931).In the validation set,the sensitivity for diagnosing gastric adenocarcinoma was 0.861(95%CI:0.771~0.945),with a specificity of 0.769(95%CI:0.683~0.841)and an area under the curve of 0.844(95%CI:0.765~0.923).Conclusion The surface microstructure,microvas-cular morphology,NLR,and PLR of gastric lesions are correlated with the occurrence of gastric adenocarcinoma.Developing a risk diagnostic model facilitates early identification and diagnosis of gastric adenocarcinoma.
8.A preliminary study on data mining techniques for utilizing the breast ultrasound database.
Yulan PENG ; Heqing ZHANG ; Jigang JING ; Buyun MA ; Xiao LU ; Chong TANG ; Shan NIE ; Ying LIU ; Yuzhou QIN ; Yan LUO
Journal of Biomedical Engineering 2010;27(4):898-901
Based on the breast ultrasound database of West China Hospital from January 1, 2002 to December 31, 2007, a study of data mining techniques for utilizing the diagnostic information of breast ultrasound and breast pathology was carried out. An innovative computerized retrieval system was invented. With the visual user interface of the system, the data of benignancy or malignancy diagnosed by ultrasound and pathologic examination, and the data on the diagnostic correlation of ultrasound and pathology were obtained, respectively. The qualities of data mining were 99. 98%-100%. By means of the retrieval system, the users can secure numerous data from the breast ultrasound database rapidly and accurately; so it contributes to the rational utilization of information from medical database for serving various medical studies. This method may also be helpful for doctors to utilize ultrasound database in other fields.
Breast Neoplasms
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diagnostic imaging
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pathology
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Data Mining
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Databases, Factual
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Female
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Humans
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Information Storage and Retrieval
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methods
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Medical Records Systems, Computerized
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Ultrasonography