Surgical Site Infection (SSI) is one of the most serious post-operative complications and therefore its prevention is extremely important. SSI risk factors were evaluated in 337 cardiac valvular surgical cases without concomitant CABG or the thoracic great vessels interventions which had been performed in our center between January 2008 and December 2010. The Center for Disease Control and Prevention definition of SSI was used for case determination. The SSI incidence was 4.7% (16 cases). Univariate analysis found statistical significance in history of cardiac surgery, LVEF, surgical procedures, operative time and morning glucose level on post-operative days (POD) 1 and 2. POD 1 morning glucose level higher than 150 mg/dl (odds ratio 4.2 ; 95% confidence interval 1.3-13.7) and operative time (odds ratio 2.0 ; 95% CI 1.2-3.5) were identified as independent factors by multiple logistic regression. According to SSI rate comparison by glucose-level, the incidence was higher when POD 2 morning glucose level exceeded 150 mg/dl as in the case of POD 1 (p<0.02). Longer operative time represented higher SSI rates in interquartile range-based comparison. This study suggested values of reducing surgical time and controlling POD 1 morning glucose level within 150 mg/dl.

A 43-year-old man was admitted for mitral valve repair. After quadrangular resection of the posterior leaflet, folding plasty was performed. Chordal reconstruction of the anterior leaflet was carried out and a 32-mm Cosgrove-Edwards ring was placed. Seven weeks after the operation, hemolytic anemia developed and serum lactate dehydrogenase elevated to 1,923IU/l. Doppler echocardiography showed only mild residual mitral regurgitation, but the regurgitation jet collided with the annuloplasty ring. The velocity of the regurgitation jet was 5.19m/s. After bisoprolol administration, the hemolytic anemia improved. However, the patient had been complaining of general fatigue; serum lactate dehydrogenase was found to be re-elevated after discharge despite the administration of bisoprolol. Therefore, re-operation was undertaken. The cause of the residual mitral regurgitation was mainly anterior leaflet prolapse. Chordal reconstruction and ring annuloplasty were re-performed. The hemolytic anemia was cured after re-operation. This case showed that a high-velocity regurgitation jet can cause hemolytic anemia, especially by colliding with an annuloplasty ring. It is important to accurately evaluate the severity, direction and velocity of the regurgitation jet by transesophageal echocardiography. It seems that the velocity of the regurgitation jet could become a parameter when deciding on the treatment plan.

A 53-year-old woman with von Recklinghausen's disease was admitted with severe pain and acute right leg swelling. The physical examination revealed neurofibromas and café-au-lait spots, typical of patients with von Recklinghausen's disease. Computed tomography and ultrasonography showed a rupture of a posterior tibial artery pseudoaneurysm. Since her complaint of pain was severe and because of the rapid progression of pseudoaneurysm, we performed an emergency operation. Under general anesthesia with the pneumatic tourniquet technique, both of the proximal and distal sides of the posterior tibial artery were ligated, and the pseudoaneurysm was resected. The postoperative course was uneventful. She was given an ambulatory discharge 26 days after operation. Histological examination revealed spindle-shaped cells infiltrating the aneurysmal wall. We diagnosed this is a vascular lesion of von Recklinghausen's disease.

A case of idiopathic enlargement of the right atrium (IERA) is described. A 28-year-old woman was admitted to our hospital because of cardiomegaly and a mass in the right atrium. She had had cardiomegaly for at least 8 years. Echocardiography showed an enlarged right atrium and a large mass. Cardiac catheterization demonstrated normal hemodynamic data. Based on these findings, we diagnosed this case as IERA and the right atrial mass was suspected to be myxoma. At operation, a markedly enlarged right atrium was found. The right atrial wall was paper-thin. Through right atriotomy, a giant round thrombus (5×4×4cm) was found. The tricuspid valve showed a normal configuration. After extirpation of the thrombus, the right atrial wall was excised and plicated. The postoperative course was uneventful. IERA is extremely rare and heart failure and sudden death have been reported. Therefore, symptomatic or complicated cases should be treated surgically.

We report a case of left internal iliac aneurysm that ruptured into the left common iliac vein and formed an arteriovenous fistula. A 79-year-old man who had general fatigue was admitted to our hospital with a diagnosis of left internal iliac artery aneurysm, left hydronephrosis, dehydration and low renal function. After dehydration and low renal function resolved rapidly by medical treatment, an enhanced computed tomography was performed. This demonstrated a 69 by 67 mm diameter left internal iliac artery aneurysm with an arteriovenous fistula. During the operation, left common iliac artery and left external iliac artery were resected and the stumps sutured. External iliac-external iliac artery bypass was performed. An occlusive balloon catheter was inserted from the left femoral vein and the balloon was dilated to patch the fistula before opening the aneurysm. After clamping the proximal artery the aneurysm was opened. Bleeding from the fistula was controlled by this maneuver and digital compression of the left common iliac vein where was proximal side of fistula. An arteriovenous fistula with a 18 by 3 mm orifice was found between the left internal iliac artery and left common iliac vein. The fistula was closed from the inside of the aneurysm. His postoperative course was uneventful.

A 53-year-old woman underwent mitral valve replacement for congestive heart failure due to mitral stenosis and regurgitation. She had been receiving hemodialysis because of diabetic nephropathy since 1993, and had had congestive heart failure since 1999. Echocardiography demonstrated mitral stenosis (MVA; 1.10cm²) and regurgitation with a severely calcified mitral annulus. Annular calcification extended to the posterior wall of the left ventricle and the base of bilateral papillary muscles. After removing all calcium from the mitral annulus to the base of the papillary muscle, the left ventricular posterior wall and mitral annulus were reconstructed by glutaraldehyde-preserved autologous pericardium. Then, a Carbo-Medics mechanical valve was placed at the mitral annulus using everting mattress sutures. Although her hemodynamics were stable, bacteremia and multi-organ failure developed 3 months after surgery and she died. Autopsy showed that the reconstructed left ventricular posterior wall and mitral annulus using glutaraldehyde preserved autologous pericardium were in excellent condition without any thrombus. No dehiscence was found at the suture line of the mechanical valve. Mitral annulus reconstruction with glutaraldehyde preserved autologous pericardium is thought to be effective for patients with calcified mitral annulus who require mitral valve surgery.

A 66-year-old woman who had percutaneous mitral valve commissurotomy 12 years before was admitted complaining of dyspnea on effort. Echocardiography showed severe mitral stenosis and regurgitation, and moderate tricuspid regurgitation associated with atrial fibrillation. Based on her past history we suspected allergy to metal, and skin patch tests showed a positive reaction to zinc, manganese, nickel, cobalt, dichromate, stainless steel, titanium alloys, and nickel-chromium-cobalt alloys. We selected an artificial organ which would not cause an allergic reaction. The St. Jude Medical standard cuff mechanical valve was the only compatible prosthetic valve. Anterolateral right thoracotomy, instead of median sternotomy, was selected. Mitral valve replacement with a 27-mm St. Jude Medical standard cuff mechanical valve and tricuspid valve annuloplasty with a 27-mm Duran flexible band were performed. Her postoperative course was uneventful. She is doing well without any allergic symptom 18 months after the surgery.

Postoperative infections should be comprehensively controlled in the context of infection control, rather than as activities of individual surgeons. We started a surgical site infection (SSI) surveillance program in 2009 in which prophylactic measures for preventing SSIs were applied. These measures were as follows : 1) screening for nasal carriage of methicillin-resistant Staphylococcus aureus ; 2) dental checks and oral screening ; 3) antibiotic prophylaxis in the intra- and postoperative period ; 4) control of glucose levels to ≤160 mg/dl in the immediate postoperative period ; and 5) early removal of surgical drain. After the introduction of prophylactic measures, we reexamined SSI surveillance and added the following prophylactic measures at the beginning of 2011 : 6) data concerning SSI and compliance with prophylactic measures for all surgical and ward staff were published monthly, and the Infection Control Team (ICT) and surgeons performed weekly ward visits to assess SSIs ; 7) recommendations were made for wearing two pairs of gloves and surgical hoods to cover the hair, scalp, ears and neck ; and 8) collaboration with diabetologists was implemented to control glucose levels in diabetics. We compared incidences of SSI in cardiovascular surgery from the periods before (469 cases, Group B) and after (118 cases, Group A) introduction of the additional prophylactic measures. Clinical characteristics of patients in each group did not differ significantly. Operative time was significantly shorter in Group A (400±116 min) than in Group B (434±145 min). Compliance with antibiotic prophylaxis in the intraoperative period improved progressively from 93% in Group B to 99% in Group A. Compliance with control of glucose levels to ≤160 mg/dl on postoperative day 1 improved progressively from 71% in Group B to 81% in Group A. Duration of drain placement was significantly shorter in Group A (2.9±1.8 days) than in Group B (3.6±2.9 days). Incidence of SSI decreased significantly from 6.0% in Group B to 0.8% in Group A. Revision of preventive measures based on the results of surveillance and enhancement of cooperation between the ICT and surgeons could help to decrease the incidence of SSI.