Objective:To explore the application effect of root cause analysis (RCA) and nursing ethics theory on improving the success rate of venipuncture blood collection in infants.Methods:In January 2016,150 infantswho were punctured for venous blood collection in the out-patient blood collection room in our hospital were selected as the control group.The root cause analysis was used to determine the root cause of the success rate of infant venipuncture blood collection,and the feasible measures were formulated.And 150 infants after 6 months of the implementation of RCA were selected as the observation group.The success rate of puncture and the satisfaction of the families were compared in both two groups.Results:The success rate of venipuncture blood collection in observation group (93.3％) was significantly higher than the control group(76.7％),and the families' satisfaction of the observation group (95％) was also significantly higher than those in the control group (70％).Conclusions:The application of root cause analysis and nursing ethics theory,effective nursing measures and psychological care can improve the success rate of infant venipuncture blood collection.

Objective:To apply theories and techniques of an image bi-valuation that we proposed in medical image. Methods: The parameters are chosen by theory and technique for gradually flattening gray/chroma spectrum we proposed,and then the image were converted into bi-valuation image based on the bi-valuation algorithms. This method was compared with Otsu algorithms and the paint software in Windows operation system. Results:The present theories and techniques had better than the function of an image bi-valuation of Otsu algorithms and the paint software in Windows operation system. Conclusion:The theories and techniques for bi-valuating an image with parameters are generalisable.

Objective:As a branch of image processing,image mining is a subject for great concern.With the development of image acquisition and storage,human can gain a lot of useful image information,but lack of effective analytic technique,so it is a focus of image mining that how to obtain useful image information and make full use of image information.So this paper gives an overview of the research and applications of image mining.Method:Firstly,it presents the concept and primary frame of image mining and the major techniques of lower layer image mining and higher layer image mining.Then,it discusses some applications in the biomedical,DNA analysis,data analysis of medical imaging and forensic medicine and so on.Result:Image mining is that the technique which can mine to discover new and valuable knowledge from vast collection of image.Conclusion:This article expounds the related technologies about image mining by our study of the image mining areas integrating the usual methods of the methods.Then,it identifies some applications in medicine and future research directions of image mining.

Dioxin,as a kind of strong carcinogenic substance,a kind of environment hormone with tremendous harm,can get into human body through food chain and accumulate in fat of animals and persons,forming serious threat to human health. Dioxin has been included in the list of monitoring objects in food part of the global environment monitoring program as a new environmental pollutant by World Health Organization. In this paper,the toxicity,the source of dioxin and its impact on human health and prevention and control measures are introduced.

A briefly introduction of action mechanism of preservatives,deterioration caused by microorganism and the commonly used preservatives in cosmetics were presented in this paper. Sample pretreatment method and instrumental analysis method were summarized also. The popular preservatives in cosmetics were parabens. The consumption of new preservatives in cosmetics (iodopropynyl butylcarbamate,diazolidinyl urea,imidazolidinyl urea) is increasing. The analysis method of preservatives by the high-performance liquid chromatography was most widespread. Regarding kathon,the sensitivity of gas chromatography is higher than that of high-performance liquid chromatography. The other analysis methods are semi-quantitative thin layer chromatography and simultaneously determination water-soluble and the fat soluble preservatives capillary electrophoresis. The methods for determination of 55 limited preservatives of Hygienic Standard for Cosmetics(in 2002 version) are still not satisfactory,more methods should be developed.

Objective To establish a method for simultaneous determination of 12 kinds of organophosphorus pesticides in water. Methods Organophosphorus pesticides in the water were extracted by liquid-liquid extraction, then analyzed with DB-1701 capillary column. In the same time, they were determined with GC by controlling the temperature and the speed of nitrogen. Retention time of the peaks was used for qualitative analysis, while external standard method was used for the quantitative analysis. Results The linear ranges of organophosphorus pesticides were 0.2～50.0 ?g/L, r≥0.999 1. The lowest detection limit was 0.009～0.04 ?g/L, the rate of recovery were 78.4%～93.9% and RSDs were 3.4%～7.5%. Conclusion This method is simple, rapid, sensitive and can efficiently separate and determine 12 kinds of organophosphorus pesticides in the water with 32.5 minutes of operation only.

Henoch-schonlein purpura nephritis (HSPN)is the most common pediatric secondary renal glomerular disease.It could play an important role in the pathogenesis and progression of HSPN that regulatory T cells decline in the children and that the differentiation of Th17 cells are maybe not able to be effectively inhibited,leading to the insufficient immunosuppressive effect and the Th17 cells overexpression.We could further study the correlation among HPSN and the quantity and functional imbalance of Th17 cells and regulatory T cells to provide more theoretical basis for clinical treatment of HSPN.

Objective To explore the prognostic factors in patients with acute respiratory failure due to chronic obstructive pulmonary disease (COPD) in EICU. Method Clinical data of 39 patients admitted to EICU from May 2005 to May 2007 were retrospectivley analyzed. Results In death group, the pulmonary artery pressure (PAP) ,creatinine (Cr) ,APACHE-Ⅱ score, and APACHE-Ⅲ score were increased (P < 0. 05) and ICU stays were prolonged (P < 0.05) ; Respiratory rate (RR) and Glasgow coma score (GCS) were decreased (P < 0.05). Conclusion PAP, Cr, APACHE-Ⅱ score,APACHE-Ⅲ score,RR and GCS predict the prognosis of the patients with acute respiratory failure due to chronic obstructive pulmonary disease.

Neonatal diabetes mellitus ( NDM ),which was often misdiagnosed as type 1 diabetes in the past,is a heterogenous single-gene genetic disease.Permanent neonatal diabetes( PNDM )is mainly associated with mutation in KCNJ11,ABCC8,and insulin associated gene instead of immunity.The most common manifestation includes diabetic ketoacidosis,intrauterine growth retardation and dehydration.Gene examination contributes to the classification of NDM and corresponding targeted therapy.Oral sulfonylurea may be used in treating patients with gene mutation of ATP-sensitive K+ channel.

The gene chips have been extensively studies and widely applied.Gene chip technology provides a powerful tool for molecular nutrition.This article reviews the rationales,classification,characteristics of gene chips,and their application in molecular nutrition.