We analyzed the laboratory detection results from the first case of human infected with avian influenza (H5N6) in Hubei Province,in order to provide a better basis for preventing and controlling human avian influenza in the future and a detected strategy for the detection of suspected cases of human avian influenza for the staff in the laboratory.The case data of epidemiological survey and related laboratory detection results of specimens of infection virus from the different time piont and kinds of specimens were analyzed by descriptive epidemiological methods.The H5N6 nucleic acid from the only early sputum specimens were detected,and while the others were not detected.In conclusion the different specimens of the doubtful H5N6 case should be collected,and the early sputum samples are very important and should be collected and detected.

Objective To analyze the monitoring results of severe fever with thrombocytopenia syndrome (SFTS) in Shiyan, Hubei province, and to provide a scientific basis for the prevention and control of SFTS. Methods Descriptive epidemiological analysis was conducted on the surveillance data of SFTS, and real-time PCR was performed for detecting SFTSV RNA. Results A total of 54 laboratory-confirmed cases of SFTS were reported in Shiyan from 2011 to 2022, including 5 deaths (9.26%). The cases mainly occurred in March to October, with a peak in April to August (85.18%). People over 50 years old were the high-risk group (94.44%), and farmers were the high-risk occupation (92.59%). The male to female sex ratio was 0.64:1. The three northern counties (Danjiangkou City, Yunyang District, and Yunxi County) were high-incidence areas (90.74%). There was no statistical difference in the positive rates of sampling between within 7 days and 8-11 days after onset (66.67% vs. 57.14%) (Fisher's precision probability test , P＝0.674 ). Conclusion The incidence of SFTS in Shiyan is mainly sporadic, dominated by middle-aged and elderly people and farmers, and shows obvious seasonal and regional characteristics . It is necessary to strengthen vector management, health education, SFTS case reporting and sample collection, and inspection management of high-risk groups, and increase prevention and control efforts in the three northern counties of Shiyan.