BACKGROUND: Removable partial denture is the main way of repairing dentition defects, and its casting materials mainly include pure titanium, cobalt-chromium al oy and Vital um 2000. OBJECTIVE: To analyze the biocompatibility of removable partial dentures made of different materials in repair of dentition defects. METHODS: Total y 120 patients with dentition defects, aged 24-68 years old, were enrol ed and underwent repair with removable partial dentures. Among these patients, 40 patients were treated with cobalt-chromium al oy-casted removable partial dentures, 40 patients with pure titanium-casted removable partial dentures, and 40 patients with Vital ium 2000 casted removable partial dentures. Al patients were fol owed up for 2 years. The chewing efficiency, coagulation, thrombosis, alveolar bone loss, patient satisfaction, and the incidence of adverse reactions, such as abutments periodontal disease and secondary caries were compared between these three groups. RESULTS AND CONCLUSION: (1) Chewing efficiency and patient satisfaction rate: Vital um 2000 group > titanium group > cobalt-chromium al oy group (P < 0.05). (2) Coagulation, thrombosis, the incidence of alveolar bone loss: Vital um 2000 group < titanium material group < cobalt-chromium al oy group (al P < 0.05). (3) Incidence of adverse reactions: Vital um 2000 group < titanium group

BACKGROUND:The laser applied in the clinical oral medicine is mainly for early diagnosis of caries, removal of carious tissue, pulpotomy for pulp bleeding, dentin hypersensitivity treatment, disinfection of infected root canals, and periodontitis treatment. OBJECTIVE:To explore the changes of basic fibroblast growth factor in inflammatory pulp after laser treatment. METHODS:Five healthy adult beagle dogs were enroled, and six teeth were randomly selected from each dog. Then, these teeth were randomly divided into three groups, 10 teeth in a group, and they were treated with laser irradiation, saline and gentamicin irrigation respectively. At days 1, 2, 3 after operation, exudates from the pulp were colected for detection of basic fibroblast growth factor expression. Meanwhile, the dental pulp was detected by hematoxylin-eosin staining and immunohistochemistry method. RESULTS AND CONCLUSION:In the al three groups, the expression of basic fibroblast growth factor at day 3 was significantly higher than that at days 1 and 2, and there were no differences between days 1 and 2. Moreover, these three groups also showed no significant differences. Under hematoxylin-eosin and immunohistochemical staining, blood vessels in the pulp cavity were in good condition and the pulp arranged tightly. These findings suggest that the laser is safe, convenient and effective for oral clinical application, and has no injury to the inflammatory pulp.

Objective To compare the efficacy of Wy10 bleaching equipment and Beyond Ⅱcold light whitening apparatus for discolored tooth.Methods 100 patients were randomed into two groups:treatment group and control group.50 patients accepted the treatment of Wy10 (treatment group),and another 50 patients accepted the treatment of Beyond Ⅱ (control group).Efficacy was measured according to the Vita classical shade guide after treatment.Sensitivity between groups were tested by SPSS11.0 software package.Results The two groups did not significantly differ in tooth shade at the end of the treatment.Significant differences in sensitivity were detected between experimental group and control group (P＜0.05).Conclusions Both of treatment with using the Wy10 and Beyond Ⅱ system shows significant clinical efficacy,and Wy10 bleaching equipment can significantly solve patients' problems due to postoperative tooth sensitivity and fear.

Objective To investigate the significance of early diagnosis and intervention in cases with severe hand-foot-mouth disease. Methods Nine severe cases were chosen from 220 hospitalized children with hand-foot-mouth disease for retrospective analysis, including onset, disease progression, the blood and cerebrospinal fluid tests, electroencephalogram data, patients' treatment responses and prognosis. Pearson X2 test and t test were utilized for statistical analysis. Results All cases showed nervous systems involved symptom, including meningeal irritation sign and (or) other pathological signs of nervous system (9 cases), drowsy (7 cases), trembling (6 cases), voiding dysfunction (3 cases), hypersensitivity(3 cases), autonomic nervous system disorders (2 cases), ataxia (1 case), left leg mild paralysis (1 case) and early stage of pulmonary edema (1 case). Early intervention, such as high dose gamma globulin, methylprednisolone, mannitol treatment restriction of fluid input, started before the development of heart and lung failure. No case died but one patient with encephalomyelitis showed hobbling left leg, which didn't recover until 6 weeks later. One case with brainstem encephalitis still showed abnormal electroencephalogram after 8 weeks follow-up but without clinical symptom. Conclusions Enterovirus 71 can cause severe hand-foot-mouth disease complicated by encephalitis, meningitis and pulmonary edema. Early active intervention before the development of neurogenic pulmonary edema can improve the prognosis and reduce the mortality.

Objective To investigate the expression of PTTG and VEGF-C in laryngeal carcinoma and the effect of angiogene-sis .Methods Immunohistochemistry was used to detect the expression of PTTG 、VEGF-C and LMVD in 60 cases of laryngeal car-cinoma and 32 cases of para-carcinoma tissue .D2 40 positive products was used to locate lymphatic endothelial cell cytoplasm and cell membrane ,and count lymphatic microvessel density (LMVD) .Results The expression of PTTG and VEGF-C in laryngeal car-cinoma was significantly higher than that in para-carcinoma tissue(P<0 .05) .In laryngeal carcinoma ,the expression of PTTG and VEGF-C were associated with differentiation ,lymph node metastasis and clinical stage(P<0 .05) ,but independent of clinical classi-fication ,smoking history ,tumor′size ,sex and gender(P>0 .05) .The expression of LMVD in laryngeal carcinoma was significantly higher than that in para-carcinoma tissue(P<0 .05) .The expression of LMVD was associated with lymph node metastasis (P<0 .05) ,but independent of differentiation ,clinical classification ,clinical stage smoking history ,tumor′size ,sex and gender ( P>0 .05) .A significantly positive relation was found between PTTG and VEGF-C(P<0 .05) .And there were positive relation between PTTG and LMVD、VEGF-C and LMVD(P<0 .05) .Conclusion PTTG and VEGF-C might play an important role in the carcino-genesis and development of laryngeal carcinoma .PTTG and VEGF-C could be a prognostic factor of colorectal cancer and a new tar-get of gene therapy .

OBJECTIVE: Ambulance personnel who witness trauma experienced by patients have been reported to experience positive changes, known as vicarious posttraumatic growth (VPTG). We examined VPTG and its relationship with social support and resilience among ambulance personnel. METHODS: The sample (n=227) was recruited from six emergency centers in China. The measures included the Posttraumatic Growth Inventory (PTGI), the Social Support Rating Scale (SSRS), and the 10-item Connor-Davidson Resilience Scale (CD-RISC-10). Structure Equation Modeling (SEM) and the bootstrapping procedure were used to examine indirect effects. RESULTS: The participants' mean score for VPTG was 68.96 (SD=15.51). Social support had significant direct effects on resilience (β=0.51, p < 0.001) and VPTG (β=0.25, p=0.001), and resilience (β=0.58, p < 0.001) had a significant direct effect on VPTG. Furthermore, social support had a significant indirect effect (0.51×0.58=0.30, p < 0.001) on VPTG through resilience. CONCLUSION: Although the nature of the work of ambulance personnel is not expected to change, the negative effects of the trauma they encounter can be reduced by providing them with more support resources and interventions to foster their resilience, which in turn, promote VPTG.
Ambulances* ; China* ; Emergencies ; Humans

Objective To analyze the quality nursing measures for upper digestion tract hemorrhage treated by gastroscopy.Methods A total of 100 patients with upper gastrointestinal bleeding admitted in our hospital were randomly divided into control group (n =50) and study group (n =50).Patients of two groups were treated with endoscopy before surgery,the control group was given routine nursing intervention,and the study group was given quality care intervention on the basis of the control group.The changes of indicators (DBP,SBP,HR) in the two groups during the perioperative period (preoperative,intraoperative and postoperative),the changes of anxiety before and after intervention,and the quality of life at 1 month after operation were compared.Results The intraoperative and postoperative DBP,SBP and HR of the study group were lower than those of the control group (P ＜ 0.05).The incidence of severe anxiety in the study group was lower than the control group (10.00％ vs.38.00％,P ＜ 0.05).The proportion of patients without anxiety was higher than that of the control group (60.00％ vs.30.00％,P ＜ 0.05).The scores of sleep,energy,emotion,physical activity,pain and social life were lower in the study group than that in the control group (P ＜ 0.05).Conclusion High quality care measures for upper gastrointestinal bleeding can stabilize the physiological indicators of patients,but also ease anxiety,and improve the quality of life.

Objective To analyze the quality nursing measures for upper digestion tract hemorrhage treated by gastroscopy.Methods A total of 100 patients with upper gastrointestinal bleeding admitted in our hospital were randomly divided into control group (n =50) and study group (n =50).Patients of two groups were treated with endoscopy before surgery,the control group was given routine nursing intervention,and the study group was given quality care intervention on the basis of the control group.The changes of indicators (DBP,SBP,HR) in the two groups during the perioperative period (preoperative,intraoperative and postoperative),the changes of anxiety before and after intervention,and the quality of life at 1 month after operation were compared.Results The intraoperative and postoperative DBP,SBP and HR of the study group were lower than those of the control group (P ＜ 0.05).The incidence of severe anxiety in the study group was lower than the control group (10.00％ vs.38.00％,P ＜ 0.05).The proportion of patients without anxiety was higher than that of the control group (60.00％ vs.30.00％,P ＜ 0.05).The scores of sleep,energy,emotion,physical activity,pain and social life were lower in the study group than that in the control group (P ＜ 0.05).Conclusion High quality care measures for upper gastrointestinal bleeding can stabilize the physiological indicators of patients,but also ease anxiety,and improve the quality of life.

Objective:To explore the effect of communication competence and psychological resilience on job burnout among Operating Room nurses.Methods:From March to June 2023, randomized clustering sampling was used to select 138 registered Operating Room nurses from four ClassⅢ Grade A hospitals in Taizhou for investigation. The survey was conducted using the general information questionnaire, Operating Room Nurses' Job Stressor Scale, Chinese version of the Connor-Davidson Resilience Scale, Nurses' Clinic Communication Competence Scale, and Maslach Burnout Inventory-General Survey. Hierarchical linear regression analysis was used to explore the effects of communication competence and psychological resilience on job burnout among Operating Room nurses.Results:A total of 138 questionnaires were sent out, and 133 valid questionnaires were collected, with a valid response rate of 96.38% (133/138). Among 133 Operating Room nurses, the job burnout score was (56.35±9.28), and the communication competence, psychological resilience, and work stress scale scores were (196.71±18.92), (78.09±18.31), and (96.37±22.47), respectively. Pearson correlation showed that job burnout among Operating Room nurses was negatively correlated with psychological resilience ( r=-0.475, P<0.01) and communication competence ( r=-0.241, P<0.01), and positively correlated with work stress ( r=0.360, P<0.01). Hierarchical linear regression analysis showed that, after controlling for other variables, psychological resilience and communication competence were the influencing factors of job burnout among Operating Room nurses ( P<0.01), which could explain 17.70% of the variation. Conclusions:The level of job burnout among Operating Room nurses is relatively high, and psychological resilience and communication competence are independent influencing factors. Managers can provide psychological counseling and support services for Operating Room nurses, offer communication competence training programs, and prevent and reduce job burnout among Operating Room nurses.

Objective:To explore the efficacy of quantitative parameters of dual-layer spectral CT in preoperative prediction of Ki-67 expression in esophageal squamous cell carcinoma (ESCC).Methods:From December 2021 to December 2022, 64 patients with histopathologically diagnosed ESCC were retrospectively analyzed at Liaoning Cancer Hospital & Institute. The expression level of Ki-67 in ESCC tumor tissue was detected by the immunohistochemical method. The patients were divided into the Ki-67 high expression group (the Ki-67 expression index≥30%, 47 cases) and the Ki-67 low expression group (the Ki-67 expression index<30%, 17 cases). The quantitative parameters of spectral CT were measured, including traditional 120 kVp CT value, 40 keV CT value, iodine density (ID), normalized iodine density (NID), and Z-effective in arterial and venous phases. Independent sample t test was used to compare the differences in the parameters between the Ki-67 high and low expression groups. The receiver operating characteristic (ROC) curve was drawn to evaluate the efficacy of each parameter in predicting Ki-67 expression. DeLong test was used to compare the area under the curve (AUC). Results:The 120 kVp CT value, 40 keV CT value, ID, and Z-effective in the arterial phase and the 120 kVp CT value, 40 keV CT value, ID, NID, Z-effective in venous phase in the Ki-67 high expression group were all higher than those in the Ki-67 low expression group ( P<0.05). There was no statistically significant difference in arterial phase NID between the two groups ( t=1.85, P=0.070). NID in the venous phase had the highest AUC in predicting high expression of Ki-67 in ESCC (AUC=0.965, 95%CI 0.923-1.000). With a venous phase NID value of 0.28 as the diagnostic threshold, the sensitivity and specificity were 93.6% and 100%. There was no significant difference in AUC between venous phase NID and venous phase ID (AUC=0.926) and Z-effective (AUC=0.909) ( Z=-1.52, 1.81, P=0.128, 0.071), but there was a significant difference of AUC between venous phase NID and 120 kVp CT value (AUC=0.719) and 40 keV CT value (AUC=0.747) ( Z=3.41, 3.30, P=0.001, 0.001). There were statistical differences of AUC between venous phase NID and each parameter of arterial phase ( P<0.05). Conclusion:The three spectral CT parameters (ID, NID, and Z-effective) in the venous phase have high diagnostic efficacy in predicting ESCC Ki-67 expression.