1.Causes and treatment of lymphatic fistulas after the radical operation of gastric cancer
Yueping LONG ; Yong LI ;
Chinese Journal of General Surgery 1993;0(01):-
Objective To investigate the causes and treatment of lymphatic fistulas(LF) after radical operation of gastric cancer . Methods We observed the clinical data of 31 cases of lymphatic fistulas after the radical operation of gastric cancer , including the amount of drainage from the abdominal cavity, the levels of hemoglobin and serum albumin, post operative morbidity and the survival rate. Meanwhile, the difference in the amount of abdominal drainage before and after using octreitide was observed in LF patients. Results The rate of complications in the LF group was significantly higher than that in the non LF group(control group) (P
2.Apoptosis of bone cells in alcohol-induced osteonecrosis of femoral head
Chinese Journal of Tissue Engineering Research 2016;20(15):2241-2247
BACKGROUND:Currently, there is a lack of effective hip preserving therapy in patients with alcohol-induced osteonecrosis of femoral head. Artificial hip replacement is the only choice for the patients whose function of the hip joint is affected by the colapse of the femoral head in the late stage. Therefore, to understand the pathogenesis of alcohol-induced osteonecrosis of femoral head is of great significance for the effective hip preserving therapy in patients.
OBJECTIVE: To review the research progress in apoptosis of bone cels in the pathogenesis of alcohol-induced osteonecrosis of femoral head both at home and abroad in recent years, so as to provide a theoretical basis for the study of the treatment of alcohol-induced osteonecrosis of femoral head.
METHODS:PubMed and Embase databases were retrieved by the first author using computer to search relevant articles addressing the effect of apoptosis of bone cells in the pathogenesis of alcohol-induced osteonecrosis of femoral head. The keywords were “osteonecrosis of femoral head and apoptosis”, “bone cell, apoptosis, gene, signal” or “osteonecrosis, alcohol”in the title and the full text. Repetitive and old literatures were excluded, and finally 40 foreign language articles were included in result analysis.
RESULTS AND CONCLUSION: In recent years, the theory of apoptosis of bone cells in the pathogenesis of alcohol-induced osteonecrosis of femoral head has been gradually recognized and has become the focus of research on the pathogenesis of alcohol-induced osteonecrosis of femoral head. Apoptosis of bone cells plays an important role in the pathogenesis of alcohol-induced osteonecrosis of femoral head. Various genes, such as p53, Bcl-2 family, tumor necrosis factor, Caspase, are crucial to control the apoptosis of bone cells. Although we have made some progresses at the gene level, there is still a lack of relevant studies on alcohol-induced osteonecrosis of femoral head due to the complexity of pathogenesis.
3.Characteristics of internal fixation implantation in treatment of comminuted patella fracture
Chinese Journal of Tissue Engineering Research 2007;0(09):-
AIM: To analyze the characteristics of internal fixation implantation therapy for comminuted patella fracture. METHODS: A computer-based search of Pubmed database and Chinese Journal Full-text Database was undertaken, and the quotations of each literature were checked after the primary screening. Inclusion criteria: the papers about the application of internal fixation materials in comminuted patella fracture, those published in authority journals within recent five years were preferred. Exclusion criteria: repeated study or Meta analysis. RESULTS: Internal fixation approach differs as the fracture type. Tension band fixation is generally accepted to treat transverse patella fracture. Kirschner wire plus tension band fixation are inferior to transverse fixation, but in comminuted fracture it can induce more complications; despite of wide application, nickel titanium patella fixator is unsuitable for comminuted fractures due to its hypersensibility and carcinogenicity; silk or steel wire loop fixation fits various comminuted fractures, but metal cerclage is predisposed to induce infection and breakage because of insufficient fixation force. CONCLUSION: There is no common way for comminuted patella fracture therapy. Further researches on material and method which can cure all kinds of comminuted patella fracture are still needed.
4.Review and Analysis on Documents about Educational System Research of Medical Schools
Chinese Journal of Medical Education Research 2002;0(01):-
The research documents about educational system of medical schools were reviewed,and after deep analysis,some inadequacy was found by means of how to learn from advanced skills and how to improve the benefit of health service.This paper also put forward the chain of thought about reform of educational system of medical schools.
5.On the relationship among the three functions of higher school
Chinese Journal of Medical Education Research 2003;0(02):-
Academic teaching,scientific research and social service are the three major functions of higher school and there is an internal logical relationship among them.To give better explanation and evaluation on the relationship among the three functions of higher school,the pa-per puts forward the theory of bearing which is based on the relevant studies and its merits and demerits.
6.Clinical analysis of 12 patients caused by long-acting anticoagulant rodenticide occult poisoning
Xiaoxia CAO ; Li LI ; Yueping ZHENG
Journal of Central South University(Medical Sciences) 2012;37(8):849-853
Objective:To explore the clinical characteristics and diagnosis and treatment of occult poisoning caused by long-acting anticoagulant rodenticides.Method:Records of 12 patients from July 2008 to April 2011 diagnosed as anticoagulant rodenticide occult poisoning,who had been misdiagnosed initially at other hospitals were analyzed retrospectively.Elements from the records included clinical symptoms and signs,laboratory findings for prothrombin time (PT) and activated partial prothrombin time (APTT),and initial misdiagnosis and treatment outcome at our hospital.Results:The clinical presentations of patients were insidious and serious,often presented as skin ecchymose,hematuria,menorrhagia and gastrointestine bleeding.Laboratory examinations showed prolonged PT and APTT; bleeding was controlled effectively by administoring vitamin K1 daily.There were statistical difference between PT and APTT before and after the treatment (P<0.01).Conclusion:Coagulation disorders might be caused by the reduced acquisition in vitamin K dependent coagulation factors,which tends to be neglected due to a hidden medical history,delayed signs of poisoning,and various organs involved.A detailed patient history and systematic review may improve the diagnostic accuracy.Once diagnosed is made,vitamin K1 should be given as soon as possible.
7.Information aggregation model for case-oriented analysis
Yueping SUN ; Haihong GUO ; Jiao LI
Chinese Journal of Medical Library and Information Science 2015;24(12):5-8
A data link-based information aggregation model was established by analyzing the dimensions, approaches, model and its application scope of case specific information aggregation according to the link between information characteristics and the link between information use processes followed by a substantial evidence analysis of information aggregation with Middle East Respiratory Syndrome as an example, which showed that the model can be used in case analysis of health field.
8.Roles of Medical Social Workers in Doctors' Social Support System
Huixin XIAO ; Zijie HUANG ; Yueping LI
Chinese Medical Ethics 1995;0(02):-
The current complex medical environment has a negative influence on doctors and also hinders the further development of healthcare industry in China.By analyzing the problems of medical social workers in doctors' social support system,this paper proposes the roles medical social workers should play in constructing a new social support system of doctors.
9.Preoperative sleep quality of inpatients and its influencing factors
Li'e LI ; Dandan ZHU ; Yueping LU ;
Modern Clinical Nursing 2013;(9):1-3,4
Objective To evaluate the preoperative sleep quality of inpatients and analyze its influencing factors.Methods A self-designed questionnaire,Pittsburgh sleep quality index(PSQI)and self-rating anxiety scale(SAS)were used to investigate the sleep quality and anxiety of 114 inpatients before operation.The two groups were compared in terms of sleep quality and anxiety.The factors influencing the sleep quality were analyzed.Results Of the 114 preoperative inpatients,72.81%(83 cases)had poor sleep quality.The PSQI scores of preoperative inpatients were significantly higher than that in the healthy individuals,but significantly lower than that in the patients with insomnia(P<0.01).The main factors affecting the quality of sleep were fear of surgery,pain and discomfort,feeling strange with the ward settings,and worry about prognosis,totally causing 89.47%of the sleep disorders. Inpatients with poor sleep quality,37.3%was found suffering from anxiety.The rate was significantly higher than that of patients with good sleep quality(P<0.01).Conclusions The incidence of poor sleep quality is relatively high among the preoperative inpatients, mainly caused by fear of surgery,pain and discomfort.In order to improve the sleep quality,it is necessary to perform psychological and comfort intervention according to the sleep status of the patients.
10.Maternal thyrotoxicosis in the first trimester: a clinical analysis of 150 cases
Shunbin LI ; Yueping JIN ; Wei QIU
Chinese Journal of General Practitioners 2016;15(1):47-50
Clinical data of 150 pregnant women,who were confirmed with maternal thyrotoxicosis during January 2010 to January 2014,including 104 cases of gestational transient thyrotoxicosis (GTT) and 46 cases of Graves disease (GD),were retrospectively analyzed;65 normal pregnant women served as controls.Patients with GD had lower body mass index (BMI) than those with GTF and normal controls [(18 ± 5),(20 ± 4) and (22 ± 4) kg/m2,respectively,P < 0.05].The frequency of thyrotoxic history and hyperthyroidism symptoms in GD patients were significantly higher than that in GTT patients [33% (15/46) vs.3% (3/104) and 52% (24/46) vs.15% (16/104),respectively,both P <0.01].In the first trimester,patients with GD presented lower TSH levels than those with GTT and controls(M =0.021,0.045and 1.660 mU/L,respectively,P < 0.05) and higher free T4 (FT4) (M =24.99 vs.19.99 pmol/L,P <0.05),free T3 (FT3) (7.10 vs.5.85 pmol/L,P < 0.05),thyroid peroxidase antibody (TPOAb) (99.22vs.4.54 kU/L,P < 0.05) and thyrotrophin receptor antibody (TRAb) (5.28 vs.0.11 U/L,P < 0.05)levels than patients with GTT.In the second trimester,there were 67% (70/104) GTT patientsand 4% (2/46) GD patients had normal TSH;and FT4 returned to normal in 82% (85/104) GTT patientsand 17% (8/46) GD patients.In the third trimester,there were 100% (104/104) GTT patients and 9% (4/46)GD patients had normal TSH;and FT4 returned to normal in 100% (104/104) GTT patients and 48% (22/46)GD patients.