AIM: To study the anti-inflammatory and antipyretic effects of total alkaloids of Aconitum sungpanense Hand-Mazz (TAS). METHODS: The inflammatory models were established by injection different inflammatory agents in mice and rats, and the fever model by the intravenous injection of vaccine of typhoid and paratyphoid in rabbits. RESULTS: TAS ( 0.3 - 0.6 mg?kg -1 ,ip) inhibited the edema of hind paw induced by injection of fresh albumen, and formaldehyde in rats, the ear swelling induced by xylene in mice, and the proliferation of granule induced by injection of agar in rats. TAS lowered the temperature of feverish rabbits. CONCLUSION: TAS shows marked anti-inflammatory effect on both acute and chronic inflammation, and antipyretic effect.

Objective:To investigate the intervention effect of total glucosides of Acanthopanax giraldii Harms(TGA) on learning and memory impairment and the mechanism in cerebral ischemic rats.Methods:The model of transient cerebral ischemic /reperfusion was made by bilateral occlusion of common carotid arteries in rats.Learning-memory ability was observed and the activities of superoxide dismutase(SOD) and the content of malondialdehyde(MDA) in brain tissue were measured in rats.Results:In Ymaze test the correct reaction frequency of model group was lower than normal group(P