0.05). Results Compared with the Open Group, the VATS Group presented significantly shorter operation time (101.4?25.2 h vs 139.6?42.5 h,t=-4.086,P=0.000), duration of postoperative chest drainage (2.2?0.8 d vs 3.0?0.9 d,t=-3.498,P=0.000), analgesic requirement time (3.0?0.5 d vs 5.5?1.2 d,t=-9.578,P=0.000), and length of hospitalization (8.0?2.4 d vs 11.2?2.3 d,t=-4.993,P=0.000). The intraoperative blood loss (185.2?153.4 ml vs 393.6?296.9 ml,t=-3.300,P=0.002) and the postoperative drainage volume (158.8?75.2 ml vs 248.2?191.7 ml,t=-2.298,P=0.025) was dramatically less in the VATS Group than in the Open Group. All the patients were cured. Follow-up observations for 1~3 months found no hemothorax, empyema, or fibrothorax in both groups. Conclusions VATS can be safely used in hemodynamically stable patients or hypotensive patients who respond to crystalloid fluids. VATS has many advantages, such as minimal invasion, little blood loss, short operating time, and quick recovery.

In this research,enzyme linked immunoassay (ELISA) was used to assay the fibrinogen (FIG) adsorbed on the Ti-O films and on the low temperature isotropic carbon (LTIC) films which were planted in the femoral arteries of 6 mongrel dogs for six months, respectively. The Ti-O films were planted in the dogs' left femoral arteries; the LTIC films as controls were planted in the dogs' right femoral arteries. The contents adsorbed in these two kinds of films were examined by scanning electron microscopy (SEM). The quantities of FIG adhered or denatured on the Ti-O films or LTIC films determined by ELISA, and the platelets adhered on the two kinds of films examined by SEM were of significant difference between the two groups. In the blood vessel, the amount of FIG adhered on biomaterial was related to its component and construction. FIG released electron to the biomaterial and induced the unfolding of C term of the gamma-chain of FIG, and the conjugation point and effect point were exposed. In conclusion, the biomaterial, which has the capability for resisting the electron release from FIG as well as for maintaining the invariable electric condition, will have excellent hemocompatibility.
Adsorption ; Animals ; Dogs ; Fibrinogen ; metabolism ; Heart Valve Prosthesis ; Histocompatibility ; Molecular Conformation ; Platelet Adhesiveness ; Prostheses and Implants ; Surface Properties ; Titanium ; chemistry