OBJECTIVE:To facilitate the construction of Chinese pharmaceutical profession associations. METHODS: We analyzed the current situation and problems existing in Chinese pharmaceutical profession association as well as the developmental experience of foreign pharmaceutical associations then put forward suggestions for the development of pharmaceutical profession associations in China. RESULTS & CONCLUSIONS: The sound development of pharmaceutical profession associations calls for the cooperated efforts of government, profession association and pharmaceutical enterprises, meanwhile its function as bridge and tie between pharmaceutical enterprises and government should be brought into full play.

Objective To observe the clinical effect of minimally invasive with AO joint anatomic locking plate under arthroscope and traditional internal fixation on treatment of severe comminuted fracture of tibial plateau.Methods Thirty-six cases of patients with severe comminuted fracture of tibial plateau were treated in Zhongshan Hospital Affiliated to Dalian University from June 2013 to June 2015 were selected.All patients received minimally invasive treatment with AO joint anatomic locking plate under arthroscope.At the same time,35 cases of patients under traditional fixation were selected as the control group.General surgery information including operation time,intraoperative blood loss,length of incision,limb shortening,knee flexion degree and knee HSS score of patients in both two groups were observed.Results The operation time,intraoperative blood loss,length of incision of the research group were (95.1 ± 20.4) min,(385.4 ± 40.7) ml and (1.9±0.7) cm respectively,(77.6±14.3) min,(456.7±45.1) ml and (4.0±1.2) cm for the control group,the differences were significant (t =4.175,6.997,9.038;P ＜ 0.05).The limb shortening,knee flexion degree of the research group were (0.9±0.7) mm and (112.1 ± 14.8) ° respectively,(2.5± 1.8) mm and (90.1± 10.6) ° for the control group,the differences were significant (t =4.962,7.183;P＜ 0.05).After treatment,the knee joint HSS score of the research groups was (84.9±9.7),(69.1±7.3) for the control group,the difference was significant(t =7.738,P＜0.05).Conclusion The clinical effect of minimally invasive treatment of severe comminuted fracture of tibial plateau with AO joint anatomic locking plate under arthroscope is significant,with smaller invasion,better postoperative recovery than traditional fixation,and can promote the recovery of neural function.

The author got an opportunity to know about the Thai traditional medicine, especially its application and efficacy in treatment of Bi syndrome via the communication with Thai healers in the duration of teaching and working in Chandrakasem Rajabhat University due to an invitation.This paper will simply discuss the similarities and differences between the treatments with traditional Thai medicine and traditional Chinese medicine for Bi syndrome in terms of their theory systems, the understanding of Bi syndrome, as well as the characteristics of therapies.And I hope this paper will provide certain help in the academic exchanges between these two traditional medicines.

Objective To discuss the present situation of nearly five years of traditional Chinese medicine for the diagnosis and treatment of children with bronchial asthma,confirmed that the curative effect of traditional Chinese medicine for the treatment of the disease is reliable,thus to provide certain theoretical basis for further research in the future.

OBJECTIVE:To provide references for Chinese drug distribution reform.METHODS:The drug distribution model in USA was briefly introduced and compared with that in China.The difficulties and orientations in Chinese drug distribution reform were put forward.RESULTS &CONCLUSIONS:Drug distribution reform should be carried out cautiously.Our government should deal well with the relationships between different interested parties and set up a reimbursement mechanism in medical institutions in order to facilitate the reform.

OBJECTIVE:To study the effect of Qinglutongbi granules on bone destruction in rats with adjuvant-induced arthritis (AIA). METHODS:AIA model was established in rats. Qinglutongbi granules were given to the model rats on day 7 for a total of 49 days. Roentgenography of joints of rats was performed for the observation of bone destruction. Synovial cells were taken from each group for cultivation of supernatant liquid, which was then added to cartilage cells that cultured in vitro. The outcome measures were proliferative response of cartilage cells, NO content and expression of antileptic type iNOS in supernatant of cartilage cells. RESULTS:Qinglutongbi granules (high, middle and low dosages) could improve the reduced bone density of joints in hind limb, widened articular cavity space and disorganization of joints in rats. Supernatant liquid that cultivated with synovial cells from AIA rats receiving Qinglutongbi granules at dosages of 7.2 g?kg-1 and 14.4 g?kg-1 could enhance the reproductive activity of chondrocytes and reduce iNOS expression as well as NO content. CONCLUSION:At a certain dosage, Qinglutongbi granules can inhibit the destruction of cartilage and bone in rats.

0.05),and 12 928.75 vs.14 262.98,respectively.Both groups had 1 alimentary tract hemorrhage case in either group but were cured on treatment.No intracranial hemorrhage was noted in either group.CONCLUSION:Yinxingdamo injection was an optimal therapy as compared with Shuxuening.

OBJECTIVE: To establish an HPLC method for the determination of diprophylline in diprophylline tablets. METHODS: The analytical column was C18 and the mobile phase consisted of methanol-water (30∶ 70) at a flow rate of 1.0 mL?min-1. The detection wavelength was 273 nm and the sample size was 20 ?L. RESULTS: The linear range of diprophylline was 8.1～81 ?g?mL-1 (r=0.999 8) with an average recovery rate of 100.01% (RSD=0.21%). CONCLUSION: The method is simple, accurate and precise, and it can be used for the quality control of diprophylline tablets.

0.05) and the cost-effectiveness ratios were 1 898.85 and 1 599.81,respectively.CONCLUSION:Levoflocaxin is superior to cefoperazone sodium/sulbactam sodium for community acquired pneumonia.

Toll-like receptor,TLR (TLR) can sense invading pathogens,the acute inflammatory response in the body,chronic airway inflammation and pathophysiology of allergic diseases and play an important role in the immune defense response.Among them,TLR2,TLR4 most prominent role and become a hot research topic.This paper summarizes the importance of TLR2,TLR4 in the pathogenesis of respiratory tract infections,and pointed out by interfering with TLR2,TLR4 signal transduction pathway or reduced TLR2,TLR4g role may help to weaken the disease or improve the prognosis,which provides a new way of thinking and clues for the treatment of clinical common diseases.