1.Diagnostic Value of the Direct Low-field MR Arthrography in the Meniscus Degeneration and Tear of Knee
Wenguang WANG ; Wenjie WANG ; Yuanzhi FU
Journal of Practical Radiology 2001;0(09):-
Objective To evaluate the diagnostic value of the direct MR arthrography in the meniscus degeneration and tear of knee.Methods Thirty subjects undefined by MR imaging having meniscus degeneration and tear of knee underwent MR arthrography.The diagnostic accurate rates in meniscus degeneration and tear by using MR imaging and MR arthrography were evaluated according to the arthroscopy results.Results The diagnostic accurate rates of meniscus degeneration and tear were 80% and 96.7% by conventional MRI scan and MR arthrography respectively.Conclusion The direct low-feild MR arthrography can improve the diagnostic accuracy of meniscus degeneration and tear of knee.
2.Effect of thymosin ?1 on percentage of T-lymphocyte subsets in in vitro peripheral blood mononuclear cells from gastric cancer patients
Xia YANG ; Feng QIAN ; Kaijun LIU ; Haiyang HE ; Yuanzhi LAN ; Yi TIAN ; Xiaolan FU ; Jian LI ; Ji ZHANG ; Zigang SHEN ; Jintao LI ; Yuzhang WU
Journal of Third Military Medical University 2002;0(12):-
Objective To investigate the effect of thymosin ?1 (T?1) on cellular immune function in gastric cancer patients through observing its treatment on the differentiation of T-lymphocyte subsets from screened peripheral blood mononuclear cells (PBMCs). Methods PBMCs were obtained by centrifugation of blood samples from 18 healthy subjects and 32 patients with gastric cancer,and then cultured in the presence of culture medium with addition of T?1 at 50,10 and 1 ?g/ml for 2 d. T lymphocyte subsets (such as CD4+,CD8+ and CD4+ CD25+ Foxp3+ T cells) and Th1/Th2 multiplex cytokines were detected by flow cytometry (FCM). Results After PBMCs isolated from healthy people and patients were incubated with or without T?1,there was no significant change in percentage of CD4+,CD8+ peripheral lymphocyte subsets and ratio of CD4+/CD8+. There was no obvious change in the percentage of CD4+ CD25+ Foxp3+ T lymphocyte subsets in the normal control,but a significant increase was observed in the cells from patients with gastric cancer after treatment (P
3.Long term follow-up results of pipeline embolization devices showing no in-stent stenosis at short-to-medium term follow-up examination
Yuanzhi LI ; Hang ZHANG ; Yajing MA ; Minglei SI ; Yu FU ; Xinbin GUO ; Linyu WANG ; Sheng GUAN
Journal of Interventional Radiology 2024;33(10):1057-1063
Objective To investigate the long-term incidence of in-stent stenosis(ISS)in patients with intracranial aneurysms receiving pipeline embolization device(PED)who showed no ISS at short-to-medium term follow-up examination.Methods The clinical data of patients,who received PED treatment at the Department of Neurointervention,First Affiliated Hospital of Zhengzhou University of China between April 2015 and June 2022,were retrospectively collected.The patients with intracranial aneurysms,who showed no ISS at the initial follow-up with DS A and completed>12 months long-term follow-up check after treatment at the same hospital,were screened out,and their relevant clinical data and imaging materials were collected.The incidence of ISS occurring in postoperative>12 months long-term follow-up was calculated.The ISS was defined as a>25%lumen loss of the parent artery when compared with its lumen size measured immediately after PED implantation.Results A total of 57 patients with 61 aneurysms were enrolled in this study,and a total of 68 PEDs were implanted.Forty-one(67.21%)aneurysms were treated by PED implantation only,and 20(32.79%)aneurysms by PED plus spring coils.The median initial follow-up time was 184.0 days(119.0,212.5).At postoperative>12 months long-term follow-up visit,DSA was employed for 35(57.38%)aneurysms,CTA was adopted for 22(36.07%)aneurysms,and 3D-SPACE sequence MR scan was performed in 4(6.56%)aneurysms.The median follow-up time was 538.0 days(407.5,678.0),and the incidence of ISS was 0%.No ISS-related neurological symptoms occurred in all patients.Conclusion In treating intracranial aneurysms with PED,the postoperative incidence of ISS is low.No ISS is found during the short-term follow-up period,and long-term follow-up results tend to indicate that no ISS events have occurred.