Objective To investigate the clinical effect of Marvelon on perimenopausal dysfunctional uterine bleeding.MethodsIn December 2014 to December 2015, 90 cases with premenopausal dysfunctional uterine bleeding in Anji people's hospital were randomly divided into the observation group and the control group, 45 cases in each group.The control group were given curettage, on the basis of the control group, the observation group was given Marvelon.The clinical efficacy was compared between the two groups.Results①The total effective rate in the observation group 91.1% was higher than that in the control group 71.1% (P<0.05).②After treatment, Estradiol (201.3±12.5) pmol/L, progesterone (1.6±0.9) nmol/L, FSH (1.3±0.2) IU/L in the observation group;estradiol (305.3±19.5) pmol/L, progesterone (2.8±1.1) nmol/L, FSH (2.9±0.9) IU/L in the control group, the differences were statistically significant between the two groups (P<0.05).ConclusionThe clinical effect is better which Marvelon was used on perimenopausal dysfunctional uterine bleeding, it is worthy of application.