30 patients (16 females 14 males; age of 7-72 years, the mean age of45. 4 years)with various pemphigus for the first time admitted to our hospitalduring the period of 1959-1979 have been studied. It was important torecognize mucous lesions in the early stage of diagnosing the disease. Itwas fouud that the disease was characterized with their living district. Thecorticosteroid therapy and early application of immunosuppressive wasdiscussed. It sbould be suggested that the local application of Rivanolointment gauze give good results.