1.Effects of whole course rehabilitation nursing intervention for stroke patients with hemiplegia
Chinese Journal of Practical Nursing 2009;25(19):4-6
Objective To explore the effects of whole course rehabilitation nursing intervention on stroke patients with hemiplegia, so as to provide evidence for the future nursing intervention for these pa-tients. Methods 92 stroke patients with hemiplegia were randomly assigned into the experimental group and the control group with 46 patients in each group. All patients in both groups received routine neurologic medical therapy and the routine care. The patients in the experimental group also received whole course re-habilitation nursing intervention including health assessment, rehabilitation consultation, health education before and after discharge and also received follow-up. Data were collected when the patients were in hos-pital within the first week and the following 3 months after discharge including the level of TC, TC, Hey, the ability of daily living, and the physical/psychological health evaluation. Results Compared with the con-trel group, the level of blood TC, TC, Hey decreased in the experimental group. In the experimental group, patients" scores of the physical health and mental health after the intervention were higher than those before the intervention. In the control group, the score in physical health domain increased compared with that be-fore intervention, but the score in psychological health domain remained unchanged. Conclusions The whole course rehabilitation nursing intervention designed by the investigator in the study can effectively de-crease the blood level of TC, TG, Hey of stroke patients, improve the ability of daily living and the quality of llfe of these patients.
2.Pathogenic mechanism of Acinetobacter baumannii and research status of corresponding vaccines
Chinese Journal of Biologicals 2023;36(2):245-
As a Gram-negative bacillus,Acinetobacter baumannii is one of the main opportunistic pathogens causing nosocomial infection,and mainly infects various human organs such as lungs,which finally causes bacteremia,pneumonia and other diseases,and seriously threatens lives of patients.People with weak immunity are the main susceptible people.The strain has strong stress resistance and multiple antibiotic resistance,making its infection a difficult problem in clinical treatment.The outer membrane complex(OMC),outer membrane vesicles(OMVs),secretory system and lipopolysaccharide of A.baumannii play an important role in the process of infection of host cells.At present,the vaccines developed against these pathogenic components can play a certain role in preventing and treating A.baumannii infection,and have a good application prospect.In this paper,the pathogenesis of A.baumannii and the current situation of vaccine development are reviewed,so as to provide a reference for the development of novel prevention and treatment methods of it in clinic.
3.How to perform the follow-up analysis of visual field test
Ophthalmology in China 1993;0(01):-
In the course of follow-up analyses of visual field test,it should take more than two visual field tests that had similar results as baseline test,and some factors should be taken into account,such as accordant testing conditions,reliable indeces,test errors and fluctuation effects,and so on.The indeces of Mean Deviation(MD)and Pattern Standard Deviation(PSD)could reflect the whole change trend of follow-up visual field test,while sensitivity value of every point and their pattern deviations could help to analyse tiny changes of visual field tests.Those statistic softwares provided by automatic perimetry should be used adequately.Through the follow-up analyses of visual field test,glaucoma doctors could adjust therapy schemes in time in order to obtain objective intraocular pressure and stabilize visual field and glaucoma.
4.Stress Resistance of Rhodiola under Freezing Injury Stress
Chinese Journal of Information on Traditional Chinese Medicine 2014;(1):91-94
Objective To study the stress resistance of Rhodiola under freezing injury stress. Methods With R.kirilowii, R.crenulata, R.Algida and R.fastigiata as the experimental materials, the effects of freezing injury stress on emerging time, duration of seedling emergence, emergence rate, surviving rate, the activity of SOD and POD were observed by field test and experimental detection. Results Before seeding, the effect of freezing injury stress on R.kirilowii was the largest, and that on R.fastigiata was the least. When injury stress happened during seedling stage, surviving rate, increase of SOD and POD activities of R.kirilowii was the least, indicating the freezing injury was severe. R.fastigiata was the best in those indexes. The stress resistance of Rhodiola was as follows:R.fastigiata > R.crenulata > R.Algida > R.kirilowii. Conclusion R. fastigiata and R.crenulata are good choice in introduction and cultivation of Rhodiola in Gannan area of Gansu province, and R.fastigiata is the best.
5.Analysis in coordination strategy between nurses and pharmacists in pharmacy intravenous admixture services
Chinese Journal of Practical Nursing 2009;25(15):68-70
Objective To disucss the coordination strategy between nurses and pharmacists in phar-macy intravenous admixture services (PIVAS) during the handling of clinical work. Methods Ques-tionnaires were adopted to investigated relative staff for information collection and analysis by combina-tion of specified post responsibility of nurses and pharmacists in PIVAS and experience from clinical work. Results We proposed the sixteen-word guideline of "clear duty, study and respect each other to achieve win- win development". Conclusions The coordination of nurses and pharmacists in PIVAS is important in clinical work, the countermeasures summarized from clinical practice has certain instructive significance to coordinate their relations.
6.Value of low-dose CT scan in follow-up of the adult patients with secondary active pulmonary tuberculosis
Journal of Practical Radiology 2014;(8):1302-1305,1347
Objective To evaluate the clinical value of low-dose scan with 1 6-slice spiral CT in follow-up of the adult patients with secondary active pulmonary tuberculosis.Methods 130 patients with secondary active pulmonary tuberculosis were enrolled CT scans in the study.Routine dose (120 mA)and the following low-dose (1 5-40 mA)scanning was used with the same tube voltage of 120Kv and other factors.Image quality,imaging characteristics of the lesions,CT dose index and dose length product of two scans were evaluated.Meanwhile,the effective dose,quantitative measurement and evaluation of differences were analyzed.Results Between the routine scan and low-dose one,no significant difference in image quality was found(P = 0.121 0).No significant differences were found between two scans in 7 imaging features including ground-glass appearance,tree-in-bud sign,consolidation, cavity,bronchiectasis,bronchial stenosis and intralesional calcification (P >0.05).The X-ray radiation dose was decreased signifi-cantly with low-dose CT.Conclusion Low-dose spiral CT shows more advances in detection of secondary active pulmonary tubercu-losis as good as the conventional doses CT,and is used in the follow-up of the pulmonary tuberculosis.
7.Effect of stromal cell-derived factor-1 on the adherence function of mononuclear cells
Journal of Leukemia & Lymphoma 2008;17(3):175-177
Objective To investigate the effects of stromal cell-derived factor-1 (SDF-1) on the adherence of mononuclear cells (MNC). Methods Mononuclear cells were isolated from cord blood and the adherent rate was assayed by using MTT with fibronectin coated in different concentration of SDF-1. Then the expression of adherent molecule VLA-4 by FACS as well as the adherent rate when MNC were cultured in vitro. Results The adherent rate of fresh cord blood MNC was (110.2±2.10) %, (128.3±2.09) %, (141.6±2.62) %, (160.8±3.84) %, (162.3±3.60) %, (165.4±2.73) %, (165.1±2.33) %. When the mass concentration of SDF-1 was 50, 100, 150, 200, 250 ng/ml. When MNC were cultured in vitro,the expression of VLA-4 was 26.37te was (160.2±6.38) %, (194.6±6.09) %, (147.5±6.86) %, (144.7±4.96) %, (118.1±3.64) %. The correlation coefficient between the adherent rate and the expression of VLA-4 is 0.826. Conclusion The adherent rate of fresh cord blood MNC increases along with the concentration of SDF-1, however, it tends to be stable when the concentration of SDF-1 reaches 100 ng/ml. When MNC were cultured in vitro with hemopoietic growth factors, the expression of VLA-4 and the adherent rate of MNC increased in the initial stage, however, the expression of VLA-4 and the adherent rate of MNC both decreased gradually along with time extending. There is positive correlation between the adherent rate of MNC and the expression of adherent molecule VLA-4.
8.AN ELECTRON MICROSCOPIC STUDY ON THE RELATIOHSHIP BETWEEN LYMPHOCYTES AND TUMOR CELLS IN TUMOR TISSUE
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(02):-
The relationship between tumor cells and tumor-infiltrating lymphocytes (TIL) in tumor tissues from 12 cases of carcinoma of various sites was studied at the electron microscope level. Only at few TIL got in touch with tumor cells by several patterns of contact. Some tumor cells contacting with lymphocytes showed destructive changes similar to that of apoptosis. These findings indicate that some TIL can kill tumor cells in vivo and the main mode of tumor cell death is apoptosis, However, there were only a few TIL in contact with tumor cells. the tumoricidal effect of TIL in tumor tissue may be very limited.
9.Status quo of international mental health financing and its implications for China
Chinese Journal of Health Policy 2014;(5):27-32
Insufficient financial investments and insufficient raised funds are a common dilemma in mental health service worldwide .The primary sources of mental health financing worldwide are taxes , social insurance , and out-of-pocket expenditure by the patient or family .Government plays the primary role in fund raising .China has a low level of mental health service and poor equity in mental health financing as well as irrational allocation of funds . Mental health financing system in China should be improved by adding the financing system into mental health law and the outline of the central mental health work while making it clear that government , especially central govern-ment, is the main subject of mental health financing .Community mental health should also have the priority over fund allocation in order to increase the efficiency of raising funds .
10.Inhibitor of apoptosis protein and strategy of tumor therapy
Jing MA ; Shoujun YUAN ;
Chinese Journal of Clinical Pharmacology and Therapeutics 1999;0(04):-
Apoptosis is a cell suicide process with a major role in development and homeostasis in bodies. Dysregulation of apoptosis, involved with inhibitors of apoptosis (IAPs), contributes a variety of disease states including cancer. The recent progress of members of IAPs family and the anticancer strategy against IAPs is reviewed in this paper.