1.Clinical effects of finasteride on preventing prostate hyperplasia with acute urinary retention
Chinese Journal of Geriatrics 2012;(12):1085-1086
Objective To study the effect of finasteride on preventing prostate hyperplasia with acute urinary retention.Methods Totally 626 patients with benign prostatic hyperplasia (BPH) were randomly divided into treatment group (316 cases) and control group (310 cases),followed up for 3 years.The incidence of acute urinary retention and prostate volume changes were analyzed.Results There were 3 cases of acute urinary retention in treatment group (1.0 %),9 cases in control group (2.9%) (x2 =5.37,P<0.05).In treatment group,the average prostate volume was reduced about 23.6% compared with before taking the medicine,on the contrary,prostate volume was averagely increased 12.3% in control group.Conclusions Finasteride can reduce the risk of acute urinary retention by narrowing the prostate volume in patients of benign prostatic hyperplasia.
2.Laparoscopic surgery for adult congenital choledochal cyst
Chinese Journal of Hepatobiliary Surgery 2012;18(5):365-367
ObjectiveTo study the feasibility,safety and efficacy of laparoscopic cyst excision and Roux-en-Y hepaticojejunostomy for adult congenital choledochal cyst.MethodA retrospective study was conducted on 7 adult patients with congenital choledochal cyst who received total laparoscopic cyst excision and Roux-en-y hepaticojejunostomy from May 2008 to February 2011 in the Department of General Surgery of Shengjing Hospital,China Medical University.ResultsAll the laparoscopic surgery was successful.The mean operation time was 210 minutes.The average intraoperative blood loss was 80 ml.All patients were out of bed within the first 24 h after surgery.The mean time to first flatus/bowel motion was 2.4 days.Except 1 patient who had small amount of bile leakage,all patients recovered smoothly without any major postoperative complications.The average hospital stay was 8.1 days.No patients suffered from abdominal pain,fever or jaundice during follow-up from 3 to 30 months.ConclusionTotal laparoscopic cyst excision and Roux-en-Y hepaticojejunostomy was a safe,efficacious,and minimally invasive procedure.
3.Influence of Electroacupuncture of Neiguan Point on Myocardial Collagen in Rats with Pressure Overload
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(06):-
[Objective] To investigate the effect of electroacupuncture (EA) of Neiguan (PC6) poinl on rnyocardial fibrosis and myocardial contents of collagen type Ⅰ and type Ⅲ in rats with pressure overload. [ Methods ] Rats were randomized to four groups: pseudo-operation group ( group A), model group ( group B) , EA group ( group C) and western medicine group (group D). Pressure-overloaded rat models were established by restriction of abdominal aortic artery. Left ventricular mass index (LVMI) and blood pressure (BP) in the four groups were observed; the plasma level of angiotensin Ⅱ (Ang Ⅱ ) was detected by radioimmunoassay and myocardial contents of collagen type Ⅰ and type Ⅲ by immunohistochemical staining method. [Results] BP, LVMI, expression levels of Ang If and collagen type Ⅰ and type Ⅲ were increased in group B as compared with those in group A ( P 0.05) . [Conclusion] EA of Neiguan point is effective in preventing and treating myocardial fibrosis induced by pressure overload.
4.Comparative studies on chemical constituents difference between single medicine decoction and mixed medicine decoction of Changweikang Granules
Chinese Traditional Patent Medicine 1992;0(10):-
AIM:To analyze and compare the chemical constituents difference between single medicine decoction(SMD) and mixed medicine decoction(MMD) of Changweikang Granules. METHODS: TLC and HPLC methods were applied to comparing the chemical constituents in SMD and MMD of Changweikang. RESULTS: Spots of TLC between SMD and MMD similar,except for some difference in the HPLC. CONCLUSION: The analyses were carried out for the first time.We found that the plus of the chemical constituents in SMD equal to MMD of Changweikang,also during the course of MMD,new constituents may be generated.Based on these,we proposed that the material base of Changweikang were the rational preparation and complementation of the effective components and the generation of new constituents.
5.Transient visual disturbance
Journal of Medical Postgraduates 2003;0(09):-
Transient visual disturbance(TVD) is caused by artery stenosis,or artery embolism and migraine,which lead to reduction of eye blood flow,retinal ischemia and hypoxia.Major clinical manifestations include amaurosis fugax and visual transient ischemic attacks(TIA).The present research situation and progression of TVD were reviewed.
6.Setting of Telephone Alarm Device in Attraction System of Automatic Control Center
Chinese Medical Equipment Journal 1993;0(05):-
Objective To set telephone alarm device in attraction system of automatic control center for timely detection of malfunctions.Methods The vacuum negative pressure meter and the delayed control line were used.The telephone key of H.F.was connected and the dial key was stored.Results Malfunctions could be detected promptly through telephone alarm.Conclusion The attraction system of the center can be examined and repaired in time,thus ensuring the medical security.
7.Development and Application of Air Pressure Slimming Unit
Chinese Medical Equipment Journal 2004;0(07):-
Objective To utilize air pressure for slimming. Methods The external counterpulsation was taken as the master, the non-motivity of which was utilized to develop special air pressure slimming unit based on the structure of human body and physiological characteristics. Results The air pressure slimming unit could work on the existing external counterpulsation with desirable results. Conclusion The air pressure slimming unit can be used not only on the existing external counterpulsation, but on other pneumatically operated equipment with control circuit. As aerobics, the working mode of air pressure slimming unit is a kind of long time and passive aerobic exercise with fixed position, frequency and mode. It is safe and the curative effect is reliable.
8.Clinical analysis of intra-articular injections of sodium hyaluronate combined with diprospan in the treatment of hip osteoarthritis
Chinese Journal of Biochemical Pharmaceutics 2015;(12):54-55,58
Objective To analyze effect of intra-articular injections of sodium hyaluronate combined with diprospan in the treatment of hip osteoarthritis.Methods 90 patients with hip arthritis patients from January 2014 to July 2015 were randomly divided into observation group and control group.45 cases in each group.Control group was given Diprospan treatment, observation group was treated with articular injection of sodium hyaluronate combined with diprospan treatment.After 4 weeks of treatment,patients were followed up and recorded hip pain VAS score and WOMAC score, lipids and C-reactive protein levels, content changes in ESR and TNF-α.Results The patients after hip pain VAS score and WOMAC scores were better than control group(P<0.05).After observation group patients lipids and C-reactive protein were lower than control group(P<0.05).After treatment ESR and TNF-αof observation group were lower than control group’s(P<0.05).Conclusion Intra-articular injections of sodium hyaluronate combined with diprospan in treatment of hip arthritis has definite clinical effect.
9.Predictive risk factors for prolonged stay in intensive care unit in patients undergoing coronary artery bypass grafting surgery
Chinese Journal of Thoracic and Cardiovascular Surgery 2011;27(2):93-96
Objective To describe the preoperative factors of prolonged intensive care unit length of stay after coronary artery bypass grafting. Methods From 1997 to 2009, 1318 patients underwent isolated CABG in our hospital. Retrospective analysis was performed on these cases. Univariate and multivariate analyses for preoperative risk factors were performed. Prolonged length of ICU stay was defined as initial admission to ICU exceeding 72 h. Results The mean age of patients ( 322women and 996 men) was (67.4±9.4) years. Of 1318 patients undergoing isolated CABG from 1997 to 2009, 205 experienced prolonged length of ICU stay. The length of ICU stay was (40.1 ± 22.5 ) hours and ( 122.6 ± 48.7 ) hours separately.Overall in-hospital mortality was higher among these 205 patients ( 13.7% vs. 1.2%, P <0.05 ). The overall mortality was 3.1%. In univariate analyses, there were statistically significant differences with respect to the percentage of CPB, total bypass time, cross-clamp time, number of distal anastomoses, use of pressor agent, use of intro-aortic balloon pump,time of ventilation and hospital mortality. The significant risk factors were age, NYHA class Ⅲ/Ⅳ, left ventricular ejection fraction(LVEF) <0.40, renal failure, cerebrovascular and/or peripheral vascular disease, chronic obstructive pulmonary disease, recent acute myocardial infarction, prior percutaneous coronary intervention, left main stenosi, three-vessels disease. The variables entered into the multivariate logistic regression were age, NYHA class Ⅲ/Ⅳ, LVEF <0.40, renal failure, chronic obstructive pulmonary disease, recent acute myocardial infarction, prior percutaneous coronary intervention, three-vessels disease. According to the outcome of multivariate logistic regression, we can conclude the model of probability forecast and create a new variable named Pre. The area under ROC curve of the new variable Pre was larger than other variables. Conclusion The main risk factors of prolonged ICU length of stay were LVEF < 0.40, recent acute myocardial infarction, renal failure and chronic obstructive pulmorary disease. The AUC of variable Pre was higher than other' s , which indicated that new variable Pre combining each variable was more valuable than single variable with respect to prediction. A predicted probability of 0. 754 was used as cut-off point for the prognostic test.
10.Advances in clinical study of postoperative radiotherapy and chemotherapy for patients with esophageal carcinoma
Journal of International Oncology 2010;37(12):919-921
Local recurrence and distant metastasis is the major factor of impacting long-term survival for patients with esophageal carcinoma after radical resection. Postoperative radiotherapy and chemotherapy is expected to reduce the rate of local recurrence and distant metastasis, but views for the value of postoperative radiochemotherapy were inconsistent in the past. In recent years, scholars have performed much more clinical studies on postoperative radiotherapy and chemotherapy and found that the combined postoperative radiotherapy and chemotherapy after surgery significantly reduces the recurrence rate and distant metastasis rate and can enhance the survival of the patients.