Medicine is a comprehensive discipline.Under the new situation,medical students are required to have integral knowledge and whole view.This article aims at evaluating the necessity of diagnosis and discusses the defects,causes and strategy in this respect.

OBJECTIVE:To discuss the disposal of essential oil in the preparation process of solid preparations containing Ligusticum chuanxiong and Angelica dahurica.METHODS:Based on pertinent literature in recent years,the disposal of essential oil in the preparation process of solid preparations containing Ligusticum chuanxiong and Angelica dahurica was discussed from aspects of chemical components,pharmacology and extraction process etc.RESULTS & CONCLUSION:It is necessary to combine research on preparation process with the pharmacological effect and pharmacodynamic action,and to formulate effective measures to control quality of the essential oil during the whole preparation process to facilitate a solution for the disposal of essential oil.

Objective:To investigate the family history of congenital heart disease (CHD) in Chogqing for studying the genetic relation of CHD families. Methods:The materials were collected from the population survey about families with more than one members being CHD patients. Map pedigrees for high-risk families were made. The probands and the first and second grade relatives were asked to fill in questionnaires and the high-risk families were analyzed. Results:In the survey of 4387 families, there were 21 high-risk families in which the disease types of the relative patients were inconsistent with those of the probands, the coincidence being 33.33%(7/121).The incidence rates of the first and second grade relatives were 16.49%(16/78),1.89%(5/265) respectively and their difference was significant ( ? 2=27.73, P

Teachers'quality is an essential factor to improve teaching,and nowadays,lack of medical English teachers has become a serious problem many medical colleges have to deal with in our country. While designing the cours "eMedical English Watching,Listening and Speaking" ,English teachers,relying on their advantages of oral communication in English,can learn more basic medical theories and knowledge,and can gradually be trained as qualified medical English teachers after several years'teaching practice.

Bronchoalveolar Lavage ; methods ; Humans

Objective To understand the effect of interventions to prevent HIV mother-to-child transmission(MTCT).Methods A survey was conducted to study preventive interventions adopted for young children delivered by HIV positive mothers including children's medication after birth,feeding practice,modes of delivery and ART for mothers.Chi-square tests was used to analyze the differences in infection rate between children in the intervention group and control group.Results The infection rate in the intervention group was 2.75%,while that in the control group was 50.00%.There was significant difference between these two groups.Conclusion Timely ART provided for mothers and their babies and using artificial feeding can effectively reduce HIV mother-to-child transmission.

In this paper,performance of decompression and low coated gas chromatographic column of non-polar liquid phases is described. Chromatographic parameters of a column packed with 0.5% OV-101 on glazing support (φ0.18～0.25mm) 302 was studied for C、C7、C8、C9 n-alkanes samples. The results showed that the column pressure 0.068 MPa was best,the column temperature for n-octane could be decreased to 52°C,column efficiency was four time as high as ordinary pressure detection.

BACKGROUND: The question whether patellar replacement is necessary during total knee arthroplasty remains controversial. The influence of different parameters, such as patellar thickness, bone bed shape, fixation column style and fixation patterns on effect of total knee arthroplasty remains unclear. OBJECTIVE: To induce the technical parameters in patellar replacement. METHODS: A computer-based line seerch of CNKI and Pubmend was performed for articles published between January 1999 and June 2009 with key words "artificial knee joint, petellar replacement" in Chinese and "artificial knee joint, arthroplasty, patellar surfacing" in English. Clinical studies of patients undergoing patellar replacement or not dudng total knee arthroplasty were included. Animal experiments were excluded. The indication and complication of patellar replacement, issues regarding patellar replacement, influence of petellar thickness reservation on artificial knee arthroplasty, prosthesis design of patellar and influence of internal fixation pattems on postoperative effect, and influence of replacement techniques on artificial knee joint were discussed in this article. RESULTS AND CONCLUSION: Currently, patellar replacement is considered to have three patterns: total replacement, no replacement and selective replacement. The shape of patella remains controversial. Bone cement is commonly used for patellar prosthesis fixation. The pdnciples of patellar replacement are as follows: to maximize patellar thickness; to maintain articular facet symmetry; to protect patellar blood transport; to ensure reasonable motion track of the patella. The indications of patellar replacement depend on protopathy, pathological change degree, prosthesis pattern, patient activity amount and body mass.

Human DAB2 interaction protein (DAB2IP) is a novel member of Ras GTPase-activating protein family. It interacts directly with disabled-2 protein (DAB2/DOC2) which suppresses growth of cancers derived from different tissues, including mammary, prostate and ovarian cancers. DAB2IP was identified as an immediate downstream effector mediated by DAB2/DOC2. DAB2IP and DAB2/DOC2 form a unique protein complex that has a negative regulatory effect on the Ras-mediated signal pathway. It is demonstrated that DAB2IP is a tumor suppressor gene inactivated by methylation in several cancers. This article reviews the structure and biological functions of DAB2IP gene as well as its potential roles in carcinogenesis and evolution.

Objective To investigate the effect of tirofiban hydrochloride in the treatment of coronary heart disease and its influence on homocysteine level.Methods 92 patients with coronary heart disease were selected as research subjects.They were randomly divided into the observation group and the control group,46 cases in each group.The control group was treated with anti-thrombotic,nitrates and other conventional western medicine.The observation group was treated with tirofiban hydrochloride based on the conventional treatment.Results The total effective rate of the observation group was 95.65%,which was higher than 82.61% of the control group,the difference was significant (χ2=4.039,P<0.05).And the homocysteine level in the observation group was (5.38±1.02)μmol/L,which was lower than (7.27±1.19)μmol/L in the control group,the difference was statistically significant (t=8.179,P<0.01).After treatment,the cardiac function CO level[(4.96±0.98)L/min],EF level[(62.48±11.16)%]and SV level[(86.37±11.47)mL]in the observation group were higher than those in the control group,the differences were statistically significant (t=2.271,2.954,2.911,all P<0.05).After treatment,the hs-CRP level[(4.25±1.32)mg/L]and Fib level[(3.14±0.73)g/L] in the observation group were lower than those in the control group,the differences were statistically significant (t=7.981,3.174,all P<0.01).ConclusionTirofiban hydrochloride in the treatment of coronary heart disease can effectively contribute to the reduction of homocysteine levels and alleviate atherosclerosis lesion progression,not only can reduce severity of myocardial ischemia and fibrinogen and high-sensitivity C-reactive protein levels,but also can reduce the thrombosis and inflammation produced by the degree of harm to the patients.