Objective To explore the changes of gastric myoelectrical activity of chronic superficial gastritis after zhizhu capsule treatment.Methods Sixty chronic superficial gastritis patients with dyspepsia were divided into two groups; the control group (n =26) was treated with pantoprazole and mosapride and the treatment group (n =34)with the same drugs combined with ZhizhuKuanzhong capsules for 2 weeks.Gastric myoelectrical activities of all patients were recorded by electrogastrography before and after treatment.The symptoms were scored in 60 chronic superficial gastritis patients according to themodified glasgow method.Results The glasgow scores before and after treatment were(6.12 ± 0.82) and (0.72 ± 0.56),respectively; they were (6.87 ±0.58) and(2.80 ± 1.10) in the control group,respectively.The glasgow scores of the treatment group were decreased more obviously than the control group (t =9.58,P ＜ 0.05).The number of cases in the treatment and control groups which the main power ratio was more than 1 before and after meals was 7 (20.59％),29 (85.29％) and 5 (19.23％),19 (73.08％),respectively.In two groups,there was significantly statistical difference in the percentage of which main power ratio was more than 1 between before and after treatment (x2 =28.57,15.17,P ＜ 0.05).After treatment,there was statistically significant difference in the percentage of normal slow wave and bradygastria before and after meal in two groups[treatment group:before meal:(63.22 ± 10.05)％,(20.35 ± 11.23)％ ;after meal:(68.52 ±13.03) ％,(18.62 ± 10.03) ％ ; control group:before meal:(50.1 ± 16.22) ％,(28.38 ± 17.25) ％ ; after meal:(54.57 ± 18.32) ％,(27.67 ± 16.27) ％] (t =2.18 ～ 3.84,P ＜ 0.05).There was no statistical differences in the percentage of tachygastria before and after meal in two groups (P ＞ 0.05).Conclusions The dyspepsia symptoms of chronic superficial gastritis might be related to the disorder of elactrogastrographic frequency.ZhizhuKuanzhong capsules can effectively improve the gastric myoelectrical activity and relieve the dyspeptic symptom of chronic superficial gastritis patients.

Objective To investigate the clinical effect of par ti al pulpotomy in the dreatment of complicated crown fracture of permanent inciso rs with pulp exposure. Methods 44 soldiers suffering from compl icated crown fracture of the incisors with exposure of pulp as a result of injur y 46 during training were enrolled for study. Altogetber teeth were treated with partial pulpotomy, and they were followed-up for 1 to 5 years. Result One of the teeth was found fo have pulp necrosis one year after treatm ent dut to falling off of the filling. The treatment failed in other toeth dut t o polpitis 2 to 4 years later. The treatment was successful in 42 teeth (91.3%) . Conclusion Partial pulpotomy was an effective treatment for c omplicated crown fracture of permanent incisors with exposureof pulp.

After the practical experiences were described in cultivating military aviation medical information research brand, providing selective dissemination of information in novelty assessment of military aviation medical literature , establishing the platform for pushing the aviation medical information , integrating the aviation medical resources , and carrying on the methodology research of aviation medical information, the successful results in reference service were summarized in novelty assessment of military aviation medical literature.

Objective To conduct the clinical and pathological evaluation on the conservative surgery in tubal pregnancy . Methods 513 cases of tubal pregnancy in this hospital from January 2006 to December 2012 were divide into the conservative sur-gery group(A ,314 cases) ,samlpintectomy group(B ,43 cases) and the medication conservative treatment group (C ,156 cases) .The hospitalization days ,HCG negative-conversion time ,cure rate ,re-pregnancy outcome ,pregnancy during 1-year follow-up were com-pared between the group A and C .In group B ,43 cases of tubal pregnancy and accomplishing fertility were firstly performed the tubal linear incision in the pregnant site ,then the biopsy was conducted after stopping bleeding and finally the salpingectomy in af-fected side was performed .The tubal electric injury degree by the unipolar or bipolar electrocoagulation and the pathological changes under light microscope were observed .Results The hospitalization days ,symptom relief rate ,HCG negative-conversion time ,cure rate and re-pregnancy outcome had statistical differences between the group A and C (P<0 .05) .Conclusion The tubal conserva-tive surgery has short hospitalization time ,high symptom relief rate ,high cure rate and few complications .The pathological observa-tion shows the localized electrocoagulation injury .The pregnancy rate after surgery is high .

Objective To study the risk factors of aortic arch calcification (AoAC) in maintenance hemodialysis (MHD) patients.Methods Retrospective analysis was performed in patients who accepted MHD ≥ 5 years.The clinical data were collected.The images of plan chest radiograph detected during followup period were reviewed by certain imaging physicians,and the AoAC score was calculated.Logistic regression model analysis was proceeded to study the risk factors of AoAC.The patients were divided into AoAC positive group (29 cases) and AoAC negative group (37 cases) respectively.The clinical parameters were compared between the 2 groups.Results Sixty-six patients (21 male,45 female) were selected.The year AoAC scores from the zeroth to fifth year were (0.013 40 ± 0.074 96),(0.018 90 ± 0.078 55),(0.118 50 ± 0.170 06),(0.157 00 ± 0.207 55),(0.166 00 ± 0.205 37),(0.175 50 ± 0.222 29) scores,progressively.There were significant differences in AoAC score from the third year compared with that of the zeroth year (Z =-3.984,-4.021,-4.017;P ＜ 0.01).Logistic regression model analysis result showed that only the age of dialysis beginning was the risk factor for AoAC (relative risk 1.177,regression coefficient 0.163,P =0.002).The age of dialysis beginning,rate of diabetic nephropathy,serum calcium-phosphate product were significantly higher in AoAC positive group than that in AoAC negative group [(59.5 ± 12.6) years vs.(52.9 ± 13.2) years,27.6％(8/29) vs.2.7％(1/37),(5.81 ± 1.63) mmol2/L2 vs.(4.13 ± 0.86) mmol2/L2].Conclusions The AoAC will aggravate with the increased duration of dialysis in MHD patients.The age of dialysis beginning is the risk factor of AoAC.

BACKGROUND:How to preserve the fertility and ovarian function in patients with procreation needs has important significance and broad application prospects. OBJECTIVE:To summarize the recent studies about ovarian tissue cryopreservation, preservation and evaluation methods, and to explore the best solution for ovarian tissue freezing. METHODS:An online computer-based retrieval of PubMed database and Wanfang database between January 1994 and January 2014 was performed by the first author. The key words were ovarian tissue, ovarian tissue cryopreservation, freezing factors in English and Chinese. Final y 59 literatures on the ovarian tissue cryopreservation technique, influencing factor of cryopreservation, resuscitation, and human ovarian tissue transplantation were included. RESULTS AND CONCLUSION:Currently, laboratory methods of ovarian tissue cryopreservation are divided into slow-rate freezing, ultra-rapid cooling and vitrification technology. The freezing effect may vary in different patients, tissue sections, cryoprotectants species, penetration time and frozen carrier. After the recovery, the histological morphology of granulosa cells and fol icles was observed. The fol icles were counted to evaluate ovarian tissue. Freeze-thaw effects were evaluated by observing the changes of subcellular structures. The apoptotic signals were also detected. Immunohistochemical analysis was applied to detect the proliferation after recovery and apoptosis-related information. Variation in the in vitro culture reflected endocrine levels. Genetic level detection was also performed. In recent years, frozen ovarian tissue is clinical y applied for the transplantation, to restore reproductive endocrine function of the patients, or get mature germ cells, thereby preserving female fertility. However, there are stil some questions about cryopreservation of ovarian tissue, which need further study.

Objective To study the formulation and preparation factors influencing in vitro release mechanism of drug from?-carrageenan/konjac glucomannan hydrophilic matrix tablets.Methods The matrix tablets containing sinomenine hydrochloride as a model drug were obtained by direct compression method or wet granulation technique.The effects of the ratios of?-carrageenan/konjac glucomannan,the amount of matrix materials,the kinds of diluent agent,tablet size,preparation method,and compressing pressure on release mechanism of the matrix tablets were studied by evaluating the n value in the Peppas equation. Results The release mechanism of the matrix tablets was non-Fickian release that coupled diffusion and erosion modle.With a decrease in the ratio of?-carrageenan/konjac glucomannan,a decrease in the amount of matrix materials,a decrease in the water-solubility of diluent agents,an increase in tablet size,and a decrease in compressing pressure,the ratio of drug diffusion was increased.Preparation method had little influence on drug release mechanism.Conclusion Drug could be slowly released from the matrix tablets containing?-carrageenan/konjac glucomannan as matrix material,the main factors influencing drug release mechanism are the ratio of?-carrageenan/konjac glucomannan,the amount of matrix materials, the kinds of diluent agent,tablet size,and compressing pressure.

AIM: The drug release characteristics of ?-carrageenan/konjac glucomannan matrix tablet were elvated by in vitro dissolution experiment. METHODS: Sinomenine hydrochloride was used as model drug,the matrix tablet containing ?-carrageenan and konjac glucomannan as matrix material were prepared by wet granulation technique. Drug release and tablet erosion in different pH values,ionic strength of media and rotation speeds were studied by in vitro dissolution experiment. The data of drug release and matrix tablet erosion were confirmed in Peppas and zero order equation,respectively. RESULTS: Among the rate of drug release in different media,0. 1 mol/L HCl was the fastest,distilled water was the second,pH6. 8 PBS was the slowest. The rate of drug release decreased with increasing the ionic strength of media(P 0. 1). The rate of drug release increased with increasing the rotation speeds(P

and each of the resistant strains was resistant at least to 5 antibiotics.13 strains out of the 28 harbored plasmids ranging from 1 to 6 in number and 105 Md to 2.7 Md in molecular weight.The plasmid with 50 Md was the most popular one in this study,which may be the epidemic plasmid in the urologic unit.It was also found that 2 different species of bacteria isloated from the patients with infection of the urinary tract showed identical plasmid profile,which indicates that these 2 patients may be associated with each other.

0.05), but BIS was markedly lower in group Ⅲ than that in group Ⅰ (P