2.Clinical analysis of the changes of plasma BNP,Mb and TnⅠin patients with acute myocardial infrction
Zhe ZENG ; Su-Hua WU ; Yu-Gang DONG ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(12):-
Objective To investigate the dynamic changes of plasma myoglobin(Mb),troponinⅠ(TnⅠ) and brain natriuretic peptide(BNP)levels in the course of acute myocardial infrction(AMI)and to detect the best marker for early diagnosis and outcome prediction.Methods Plasma Mb,TnⅠand BNP levels were measured in 49 patients with AMI both before and after thrombolysis therapy and 32 controls.Results Plasma levels of all the three markers were significantly higher in the AMI patients than those in the controls(P
4.Effect of Paishitang Combined with Tamsulosin Hydrochloride on Upper Urinary Calculi after Extracorporeal Shock Wave Lithotripsy
Taisheng LIANG ; Xiangdong LUO ; Gang WU ; Botao TANG ; Yu DONG
Progress in Modern Biomedicine 2017;17(23):4491-4494
Objective:To explore the clinical effect ofpaishitang combined with tamsulosin hydrochloride on the patient with up per urinary calculi after extracorporeal shock wave lithotripsy (ESWL).Methods:120 cases with upper urinary calculi in our hospital from January 2015 to September 2016 were selected and divided into two groups according to the random number table,60 cases in each group.ESWL was given to both groups of patients and provided with tamsulosin hydrochloride postoperation,then paishitang were additionally given to the patients in the observation group.The clinical effect and changes of serum creatinine (Scr),neutrophil gelatinase as sociated lipocalin (NGAL),cystatin C (Cys-C) and glomerular filtration rate (GFR) levels before and after treatment were compared between two groups.Results:The total effective rate of observation group was 96.67%,which was 86.67% in the control group,no signifi cant difference was found in the total effective rate between the two groups(P<0.05).The stone discharge rate was 95.00% in the observation group,which was significantly higher than that of the control group (P<0.05);the incidence rate of renal colic was 6.67%,which was significantly lower than that of the control group(P<0.05),the stone discharge time and the duration of hematuria were significantly shorter than those in the control group (P<0.01).There was no significant difference in the recurrence rate between the two groups within one year (P>0.05).The serum NGAL and Cys-C levels of both groups were gradually increased while the GFR levels were gradually decreased on the 1st,2nd day postoperation,but all the index mentioned above gradually recovered on the 3rd day postoperation.The levels of NGAL and Cys-C in the observation group were significantly lower than those in the control group on the 1st,3rd day postoperation while the GFR was significantly higher in the observation group than those of control group on the 1st,3rd day postoperation(P<0.01).No significant difference was found in the Scr at different time points postoperation between two groups(P>0.05).Conclusion:Paishitang combined with tamsulosin hydrochloride had significant clinical effect on thpatient with upper urinary calculus after ESWL and could effectively improve the renal injury induced by ESWL.
5.L1-L2 complete traumatic fracture-dislocation of the lumbar spine: a case report.
Gang-xiang WANG ; Zhi-gang WANG ; Hai-dong ZHOU ; Hong-yu XU
China Journal of Orthopaedics and Traumatology 2015;28(9):868-869
Adult
;
Humans
;
Joint Dislocations
;
surgery
;
Lumbar Vertebrae
;
injuries
;
surgery
;
Male
;
Spinal Fractures
;
surgery
6.Mucoepidermoid carcinoma of the tracheobronchial tree: CT findings
Sen JIANG ; Xiaohua ZHU ; Xiwen SUN ; Chang CHEN ; Hui ZHENG ; Bing JIE ; Dong YU ; Gang PENG
Chinese Journal of Radiology 2010;44(1):20-23
Objective To explore the CT findings of mucoepidermoid carcinoma (MEC) of the tracheobronchial tree and improve the diagnostic accuracy. Methods The CT images, histopathological and clinical data in 24 patients with pathologically proved MEC of the tracheobroncbial tree were retrospectively analyzed. Results The clinical symptoms included cough, sputum, fever, wheezing, chest pain and hemoptysis. The patient was proved to be low-grade (n=19) and high-grade (n=5) MEC histopathologically. One lesion was located in trachea, 6 in main bronchus, 12 in lobar bronchus and 5 in segmental, subsegmental and distal bronchus. The tumor presented as no-invasive endotracheobronchial well-defined round-like nodule (n=13, locating in lobar and higher bronchus) and columnar sharp (n=3, locating in main bronchus), or intra-and-extraluminal well-defined round-like nodule or mass (n=6, locating in lobar and lower bronchus) and irregular mass with invasive pattern (n=2, high-grade type). The density of lesion was similar to the muscule and the calcification within lesion was showed in 4 patients on non-enhanced CT. The lesion had marked enhancement in 17 patients on enhanced CT. Obstructive changes were found in 20 patients. Conclusion MEC of the tracheobronchial tree is usually low-grade malignancy and locates in main and lobar bronchus with no-invasive well-defined airway mass, marked enhancement and calcification on CT.
7.Angiographic manifestation and transcatheter arterial embolization of proper esophageal artery in hemoptysis
Sen JIANG ; Xiaohua ZHU ; Xiwen SUN ; Wenxiang ZHI ; Bing JIE ; Zhengqian YOU ; Dong YU ; Gang PENG
Chinese Journal of Radiology 2008;42(6):641-644
Objective To investigate the angiographic manifestation of the proper esophageal artery (PEA),the hish risk factom for the presence of the anomalous PEA in hemoptysis and to evaluate the safety of transcatheter aaefial embolization(TAE) of the PEA using gelatin sponge(GS).Methods Selective esophageal arteriography WSS performed in forty-three patients with hemoptysis,including 15 cases of pulmonary tuberculosis,18 cases of bmnchiectasis,7 cases of posttuberculous bronchiectasis and three cases of lung cancer. One case experienced failure of bronchial arterial embolization. The angiographic manifestation of the PEAs Was studied.The complications of the procedure and clinical results were observed in the patients who underwent TAE using GS.Results Thirty-nine PEAs were catheterized selectively in 37 patients(86.0%).Eighteen anomalous PEAs(46.2%)were catheterized selectively in 17 patients (45.9%).The anomalous PEAs showed tortuosity,dilatation,hyperplasia,shunting with pulmonary artery and anastomosis with the bronchial artery.All lesions involved basal segment of inferior pulmonary lobar. Bronchiectasis Was the most frequent disease for PEA abnormality. No complications occurred and satisfactory curative effect Was achieved with TAE of the anomalous PEAs.Conclusions It is necessary to perform selective proper esophageal arteriography when the lesion involves basal segment of inferior pulmonary lobar in hemoptysis.Supplemental TAE of the anomalous PEA using GS is safe and valuable in the management of hemoptysis.
8.Comparison of the effectiveness between radiofrequency ablation and microwave ablation in treating uterine leiomyoma
Li YU ; Xing'an YANG ; Gang WANG ; Junjie DONG ; Tongwei ZHU ; Zhiya FENG ; Huijin ZHAO
Chinese Journal of Ultrasonography 2014;23(2):138-142
Objective To investigate the efficiency of radiofrequency ablation (RFA) and microwave ablation (MWA) in treating uterine leiomyoma.Methods The clinical data of thermal ablation with RFA and MWA were retrospectively analyzed in 42 patients.All patients were followed up at least 12 months to observe the therapeutic effects after the treatment.The changes of vital signs and the size of uterine leiomyoma,the score of uterine leiomyoma symptom and quality of Iife(UFS-QOL) were compared after RFA or MWA,the two thermal ablations techniques of clinic efficiency and influence on complications were analyzed.Results 23 patients received treatment of RFA and 19 patients received MWA,the visual analogue scale(VAS)during operation and postoperation were statistically significant differences between the two groups(P <0.05).The sizes of uterine leiomyoma were significantly reduced after the thermal ablation,the differences of volume within two groups in different time were statistics significance(P <0.05),but there were no statistics significance differences between two groups (P >0.05).The symptoms in two groups were improved significantly after treatment and the scores of UFS-QOL were no statistics significance differences between two groups (P >0.05).Conclusions Both of RFA and MWA have significant clinic efficiency in treating uterine leiomyoma.Compared with MWA,RFA with lower adverse reactions during operation and postoperation.
9.Effect of rhBMP-2 on the Osteogenesis of Osteoblast Compounded Chitosan
Ai-Jun ZUO ; Dong-Chun LIANG ; Bao-Li WANG ; Gang GUO ; Jing-Yu ZHANG ;
China Biotechnology 2006;0(05):-
Recombinant human BMP-2 was compounded with chitosan/gelatin/hydroxyapatite(HCG) scaffold and the complex was sterilized by 60Co radiating. Osteoblast isolated from cranial bones of newborn rat was primary cultured and seeded onto the complexes. 3 days after culturing, scanning electron microscope(SEM) was applied to detect the compatibility of the cell with the complex. SEM showed osteoblast attached closely with the complex and grew well in its pores. Then the complexes with osteoblast modification were implanted into athymic nude mice subcutaneously. 8 weeks after implantation, X-ray photograph and histological observation were applied to detect the bone formation of the complexes. Under X-ray a high-density areas consistent with the shape of the implanted complex could be seen. Histological observation also proved there was bone formation in the interspace of the complex. A conclusion was drawn that rhBMP-2 compounded HCG scaffold had good osteogenesis ability in vivo.
10.Analysis of influence factors on the elasticity measurement of focal liver lesions with real-time shear wave elastography
Yi SONG ; Jingliang CHENG ; Ruifang ZHANG ; Yu LIU ; Gang DONG ; Quan ZHENG ; Zhengguang CHEN
Chinese Journal of Ultrasonography 2016;25(7):589-592
Objective To study the influence factors of real-time shear wave elastography(SWE) on the elasticity of focal liver lesions (FLLs) measurement.Methods The mean Young's modulus of 160 FLLs were measured by SWE.The relation between elasticity with different aspects of FLLs were analyzed including postures (supine and left lateral position),respiratory phases (end of inspiratory and expiratory),the probe position (rib and intercostal space) and different operators.Results There were significant differences between different postures and respiratory phases in the elasticity measurement of FLLs by SWE (P <0.05).There was no significant difference between robe position and different operators in the elasticity measurement of FLLs by SWE(P >0.05).Conclusions The postures and respiratory phases can impact the elasticity measurement of FLLs by SWE.