Recently the National Science Foundation of China (NSFC) has put forward some measures to promote the development of women science and technology (S&T) talents.The paper analyzes the NSFC funded projects undertaken by women S&T researchers at Pekiing University Health Science Center from 2006 to 2010.To address the problems revealed in the analysis,the paper proposes the suggestions to further develop women S&T talents with the support of National Science Foundation of China.

This paper analyzes the distribution and achievements of the Science Foundation for Youth undertaken by female scientists at Peking University Health Science Center from 2002 to 2012.It reveals the importance of the Science Foundation for Youth in the development of female scientists.

Thyroid cancer is the most common endocrine gland malignanct tumor. Numerous studies have found that the content of peripheral blood circulating RNA in various cancer types is aberrantly expressed, which could be a potential biological diagnostic marker and therapeutic target. Tissue-speciifc messenger RNA has a dysregulated expression and may be used for the diagnosis and residual/metastatic detection of thyroid cancer. Recent studies have showed that non-coding RNA (ncRNA) could act as oncogene or tumor suppressor gene in bacteria, fungi and mam-mals. It plays a regulatory role in occurrence and development of tumors and stably exists in peripheral blood. It is hopeful that it will become a new marker for diagnosis of tumors. This review introduces some latest research progress on circulating RNA associated with thyroid cancer; and emphatically discuss the role of mRNA, microRNA (miRNA), long non-coding RNA (lncRNA) and circular RNA (circRNA) in thyroid tumorigenesis and metastasis.

Objective To investigate the value of three-dimensional color power angio(3D-CPA)in the prenatal diagnosis of pernicious placenta previa (PPP ) with placenta increta.Methods The ultrasonographic findings of PPP with placenta increta diagnosed in our hospital by 2D-CDFI and 3D-CPA were reviewed and compared with pathologic histology examination.For each of the two imaging methods, sensitivity,specificity,positive predictive value and prenatal diagnose accordance rate were summarized. Results For 3D-CPA,sensitivity,specificity and positive predictive value were 91.1%,88.9% and 93.3%, respectively.The results of 3D-CPA were higher than those in 2D-CDFI (sensitivity 76.4%,specificity 66.7%,positive predictive value 81.5% ),and were statistically significant (P <0.05 ).The diagnose accordance rate of 3D-CPA was statistically higher than that of 2D-CDFI (90.4% vs 73.0%;P <0.05). Conclusions 3D-CPA can display abnormal vascular reconstruction between the placenta and uterine wall from various angles,and is more accurate than 2D-CDFI.3D-CPA plays an important role in the prenatal diagnosis of PPP with placenta increta.

[Summary] Gender difference study of meniscus injury shows certain clinical significance in understanding epidemiologic characteristics of meniscus injury .Several large amount case studies demonstrated that the risk of meniscus tears was significantly higher in male than in female .However , in certain kinds of sports and special types or locations of meniscus tears , especially in medial meniscus posterior root tear ( MMPRT ) , there were more females than males .Further large amount case studies were needed for a deeper understanding of meniscus tears .In this paper,we reviewed the current situation and progress of gender difference of menisus tear .

Objective To observe the effect of ShenQi Wuweizi Tablet (Tablet composed of pilose asiabell root, astragalus root, and schisandra fruit) on anxiety before college entrance examination.Methods Totally 227 patients were randomized into a treatment group (113 cases, treated with Shenqi Wuweizi Tablet, 3 tablets each time and 3 time a day), and a control group (114 cases, treated with alprazolam, 0.4 mg each time and 3 times a day). The treatment course was 6 weeks for both groups. Before treatment and at the end of the 1st, 2nd, 4th and 6th week of treatment, the clinical effect was assessed with Hamilton Anxiety Scale (HAMA) and Clinical Global Impression (CGI), and Self-Rating Anxiety Scale (SAS). And at the same time, the untoward reactions was also observed.Results At the end of the 1st week of treatment, the HAMA score was significantly decreased in the control group (P

Sepsis refers to the infection caused by systemic inflammatory response syndrome.Sepsis is one of the leading causes of death in critically ill patients in the ICU and its morbidity and mortality are increasing year by year globally.According to statistics,in China,the incidence of sepsis in ICU is 8.68％ and the mortality rate can be as high as 44.7％,therefore,severe sepsis in the field of medicine to become one of the problems to be overcome.MicroRNAs (miRNAs) play an important role in the pathogenesis of sepsis through the TLRs / NF-κB signaling pathways,which play an important role in immune regulation.In this review,the progress of miRNAs involved in TLRs signaling pathway in sepsis is reviewed.

Objective To study Evaluation of serum soluble ST2 protein and brain natriuretic peptide(NT-proBNP)in patients with acute heart failure and prognosis of patients with acute heart failure.Methods Fifty cases patients with acute heart failure from April 2014 to April 2015 in the First Hospital of Traditional Chinese and Western Medicine of Beijing were researched.Detection of all patients with serum ST2,NT-proBNP,50 patients with acute heart failure were divided into heart failure group,50 healthy persons were selected as the control group.The control group and the observation group general heart failure data,the observation group and the control group of cardiac biomarker blood level,cardiac function level NT-proBNP blood concentration level,classification of cardiac function between ST2 blood concentration level were compared.Results Cr,BUN of heart failure group were higher than the control group,there was no significant difference between other indicators(P＞0.05).ST2((0.46±0.07)ng/L)in heart failure group was lower than the control group((0.66±0.20)ng/L),NT-proBNP((4160.20±57.49)ng/L)was higher than the control group((58.97±4.39)ng/L),heart function IV NT-proBNP blood concentration of the highest(9 428.29±75.93)ng/L,followed by grade III(1 921.01±30.27)ng/L,the second lowest(321.02±16.80)ng/L,(P＜0.01).Heart function IV level ST2 blood concentration was the highest(1.95±0.69)ng/L,followed by grade III(1.27±0.61)ng/L,class II minimum(0.78±0.24)ng/L(P＜0.01).Conclusion The serum ST2 and NT-proBNP are used to detect the patients with acute heart failure,can provide accurate diagnosis basis,has a very important value judgment on the classification and prognosis.

Acupuncture Therapy ; Adult ; Diabetes Complications ; microbiology ; therapy ; Female ; Humans ; Middle Aged ; Urinary Tract Infections ; microbiology ; therapy

Objective To explore the efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPS) in the treatment of hepatorenal syndrome (HRS).Methods From January 2009 to December 2012,the clinical data of three type 1 HRS cases and five type 2 HRS cases received TIPS operation were collected.The volume of 24 h urine,liver and renal function,and the occurrence of complications of portal hypertension were recorded and followed-up.Wilcoxon rank sum test was performed for non-normal distributed measurement data.Results TIPS of all the patients was successful and combined with devascularization in four patients.Before operation,the serum creatinine and volume of urine was 204.0 (180.8,229.8) μmol/L and 810 (600,925) mL,seven days after operation was 160.7 (120.2,184.0) μmol/L and 1 300 (975,1 500) mL,respectively,and the differences were statistically significant (Z=-2.1 and-2.2,both P＜0.05).One month after operation,renal function of five patients recovered to normal.At the 7th day after operation,total bilirubin level of three patients increased and that of two patients decreased to the preoperative base line value at one month and three month.Mild or moderate hepatic encephalopathy occurred in three patients after operation and relieved after medicine treatment.At 6th month after operation,two of three type 1 HRS patients survived.Of five type 2 HRS patients,one received liver transplantation at 6th week after operation,three of the left four cases survived at the 6th month after operation.Conclusion After safety and efficacy were evaluated,TIPS may be one of the methods used for the treatment of HRS.