Objective To investigate the effectiveness of radio gu ided surgery (RGS) in lung carcinoma by using ~18F-FDG. Methods Forty mice bearing lung adenocarcinoma were divided randomly into two gro ups according to presence or absence of the lung metastasis. A dose of 200?l (1 00?Ci) of ~18F-FDG was injected via the tail vein. The external radioimmu nography was performed after injection. All viscerae and tumor were detected i n vivo by means of a hand-held gammaray-detecting probe (GDP), and the radio active distribution was analyzed with the well-gammaray detector. Resul ts The tumor images in mice were clear, and the images were best at two hours after injection. The values of %ID/g of tumor and heart obtained by well -gammaray detector were higher than those of other organs. Ratios of tumor/norm al tissue (T/NT) except cardiac muscle being detected by GDP ranged from 3.71 t o 13.57. There was a significant difference between the radioactivity of lung t issues in lung metastasis group and that of control group (P

The purpose of this study was to evaluate the features of mediastinal lymph nodes in lung cancer patients during endoscopic ultrasonography(EUS), and to establish the clinical method for the preoperative staging of lung cancer using EUS. The EUS patterns of 103 lymph nodes in 21 patients with lung cancer were evaluated. Confirmation of benign and malignant lymph nodes was obtained by surgical resection and pathology. The following features were compared between benign and malignant lymph nodes: short axis , long axis, distinct margins and the shape of nodes. The results showed that all of the lymph nodes were hypoechoic. Both the short axis greater than 1.0cm and distinct margins or round shape independently predicted malignant invasion ( P

Acute Disease ; Humans ; Nervous System Diseases ; diagnosis ; therapy ; Organophosphate Poisoning ; diagnosis ; therapy

Adult ; Dermatitis, Contact ; Dimethylformamide ; poisoning ; Female ; Humans

Amylases ; blood ; Herbicides ; poisoning ; Humans ; Lipase ; blood ; Paraquat ; poisoning ; Poisoning ; blood

Adult ; Humans ; Male ; Nitrogen Oxides ; poisoning ; Occupational Exposure

Adult ; Burns ; etiology ; Humans ; Male ; Middle Aged ; Paraquat ; adverse effects ; Scrotum ; injuries

Digestive System ; drug effects ; pathology ; Humans ; Paraquat ; poisoning

To prepare salvianolic acid phospholipid compound. With the compound of salvianolic acids and soybean phospholipid as the index, mono-factor experiment and orthogonal design experiment were conducted to screen its technical parameters. According to the results, the optimal preparation conditions of salvianolic acid phospholipid compound were that THF were taken as the reaction solvent, the concentration time was 3 h, the reactant concentration was 5 g x L(-1), the mass ratio of salvianolic acids and phospholipid was 1: 1.5, and the reaction temperature was 40 degrees C. The oil/water partition coefficient of the prepared salvianolic acid phospholipid compound significant increased in water and buffers with different pH values. The results of phase analysis such as DSC, XRD and FTIR indicated that salvianolic acids existed in phospholipid in an amorphous state.
Alkenes ; chemistry ; metabolism ; Chemical Phenomena ; Chemistry, Pharmaceutical ; methods ; Intestinal Absorption ; Phospholipids ; chemistry ; Polyphenols ; chemistry ; metabolism ; Soybeans ; chemistry ; Temperature

Acute Disease ; Adult ; Humans ; Male ; Occupational Diseases ; Phosgene ; poisoning