1.Clinical observation of percutaneous interventional radiofrequency thermocoagulation target ablation combined with nerve block in the treatment of 150 cases of intervertebral disc herniation
Jinning YUAN ; Zehong XING ; Youquan FENG
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):395-396,400
Objective To explore the effect of percutaneous interventional radiofrequency thermocoagulation target ablation combined with nerve block in the treatment of lumbar disc herniation, and to provide reference for clinical application. Methods Randomly selected from May 2015 to May 2017 treatment of lumbar disc herniation in 150 cases, according to the different treatment methods were divided into observation group and control group. The observation group of 78 cases, including percutaneous interventional radiofrequency thermocoagulation target ablation combined with nerve block treatment; the control group of 72 cases, simply accept the nerve block treatment. The degree of lumbar dysfunction was evaluated by Osw estry Lumbar Dysfunction Index (ODI) before and after treatment. The efficacy of the two groups was evaluated by modified MacNab score. Adverse reactions were observed during the two groups. Results There was no significant difference between the two groups. After 2 weeks of treatment, the scores of ODI were significantly lower than those before treatment (P<0.05). The ODI score of the observation group was significantly lower than that of the control group (P<0.05). The effective rate was 96.2% (75/78) and the excellent and good rate was 91.03% (71/78). The effective rate was 90.28% (65/72) and the excellent and good rate was 65.28% (47/72). The excellent and good rate of the observation group was significantly higher than that of the control group (P<0.05). There were no significant adverse reactions in the two groups. Conclusion Percutaneous interventional radiofrequency thermocoagulation target ablation combined with nerve block treatment of lumbar disc herniation significantly, high safety.
2.Expression of matrix metalloproteinase-9(MMP-9) and tissue inhibitor of metalloproteinase-1(TIMP-1) in gastric carcinoma
Yanming ZHOU ; Yumin LI ; Feng ZENG ; Youquan ZHU
Chinese Journal of Current Advances in General Surgery 1999;0(02):-
Objective: To explore the expression and significance of MMP-9 and TIMP-1 in gastric carcinoma.Methods: S-P immunohistochemical method was used to examine the expression of MMP-9 and TIMP-1 in 47 specimens of gastric carcinoma.Results: MMP-9 and TIMP-1 were expressed predominantaly in the peritumor stromal cells than tumor cells themselves.The expression level of MMP-9 and TIMP-1 correlated with lymph node metastasis (P0 05).Conclusion: The results suggests that MMP-9 and TIMP-1 might be important biological makers for determining the malignant behave of gastric carcinoma.
3.The Spondylolysis of Lumbar Spine:CT Diagnosis,Its Clinical Signifieance and the Improvement of Technique of CT Scan
Youquan FENG ; Zhiguang DIAO ; Zhen TANG ; Yonghong ZHOU ; Guoqing LI
Journal of Practical Radiology 2001;0(09):-
Objective To evaluate the diagnostic value of CT in the spondylolysis of lumbar spine and improve the technique of CT scan.Methods The CT appearances of the spondylolysis of lumbar spine were analyzed in 20 cases.Results CT could demonstrate the spondylolysis and its abnormal features that led to compress nerve root.Conclusion CT scan plays an important role in the diagnosis of the spondylolysis of lumbar spine and in selecting treat methods.Technique of CT scan improved can depict the specific feature of spondylolysis truely.
4.Pathological changes of Vessels Following Experimental Anastomosis with Large Blood Vessel Anastomat
Changwen QIAN ; Hengwen YANG ; Junxi FENG ; Yingbing LIU ; Deqiong LI ; Youquan GUO ; Jintai WANG ;
Journal of Third Military Medical University 1983;0(04):-
The thoracic aorlae of 39 goats and the inferior venae cavae of 9 goats were anastomosed experimentally with the Large Blood Vessel Anastomat. The pathological changes of these vessels were observed dynamically within one year after the operation. It was found that the Large Blood Vessel Anastomat was rather effective. The vessels anastomosed with this instrument showed a better result than those anastomosed with manual suture.