1.Clinical observation on treatment for postoperative metastasis of gastric cancer by Jianpi Huoxue Jiedu prescription
Youqi XU ; Huining XUE ; Xiaoqiu ZHU ; Xiaodong CHEN
Journal of Integrative Medicine 2003;1(3):192-4
OBJECTIVE: To study the effect of Jianpi Huoxue Jiedu (JPHXJD) prescription on prevention of the postoperative metastasis of gastric cancer and to observe the changes of immunity and whole blood viscosity after treatment. METHODS: JPHXJD prescription and chemotherapy were administered to the treated group for 12 successive months, while only chemotherapy was given to the control group. RESULTS: The effective rate of anti-metastasis in the treated group was obviously better than that in the control group. In the aspects of enhancing Karnofsky scores, reducing whole blood viscosity and improving immunity after treatment, the treated group was better than the control group (P<0.05). CONCLUSION: JPHXJD prescription combined with chemotherapy shows apparent effect on anti-metastasis. It can improve the quality of life of the patients, lower the whole blood viscosity and improve the immunity function.
2.The effects of using the Xinhuang Pian application to cure phlebitis after chemotherapy
Jinghua XU ; Shuluan SUN ; Yayan ZENG ; Xingsheng CAI ; Suping YANG ; Youqi CHEN
Chinese Journal of Practical Nursing 2006;0(24):-
Objective To study the effects of using the Xinhuang Pian application to cure phlebitis after chemotherapy, and then make out the proper therapeutic regimen. Methods Divided 130 patients with phlebitis after chemotherapy into the experimental group ( 69 cases) and the control group ( 61 cases) randomly. The Xinhuang Pian application was used in the experimental group, while the routine nursing method was used in the control group. Results The curative ratio in the experimental group and the control group were 92.75% and 32.79% respectively, the significant different was existed between them,P
3.ERRATUM: Comparison between Craniospinal Irradiation and Limited-Field Radiation in Patients with Non-metastatic Bifocal Germinoma
Bo LI ; Wenyi LV ; Chunde LI ; Jiongxian YANG ; Jiajia CHEN ; Jin FENG ; Li CHEN ; Zhenyu MA ; Youqi LI ; Jiayi WANG ; Yanwei LIU ; Yanong LI ; Shuai LIU ; Shiqi LUO ; Xiaoguang QIU
Cancer Research and Treatment 2021;53(2):607-
4.ERRATUM: Comparison between Craniospinal Irradiation and Limited-Field Radiation in Patients with Non-metastatic Bifocal Germinoma
Bo LI ; Wenyi LV ; Chunde LI ; Jiongxian YANG ; Jiajia CHEN ; Jin FENG ; Li CHEN ; Zhenyu MA ; Youqi LI ; Jiayi WANG ; Yanwei LIU ; Yanong LI ; Shuai LIU ; Shiqi LUO ; Xiaoguang QIU
Cancer Research and Treatment 2021;53(2):607-
5.Comparison between Craniospinal Irradiation and Limited-Field Radiation in Patients with Non-metastatic Bifocal Germinoma
Bo LI ; Wenyi LV ; Chunde LI ; Jiongxian YANG ; Jiajia CHEN ; Jin FENG ; Li CHEN ; Zhenyu MA ; Youqi LI ; Jiayi WANG ; Yanwei LIU ; Yanong LI ; Shuai LIU ; Shiqi LUO ; Xiaoguang QIU
Cancer Research and Treatment 2020;52(4):1050-1058
Purpose:
Whether craniospinal irradiation (CSI) could be replaced by limited-field radiation in non-metastatic bifocal germinoma remains controversial. We addressed the issue based on the data from our series and the literature.
Methods:
Data from 49 patients diagnosed with non-metastatic bifocal germinoma at our hospital during the last 10 years were collected. The Pediatric Quality of Life Inventory 4.0 was used to evaluate health-related quality of life (HRQOL). Additionally, 81 patients identified from the literature were also analyzed independently.
Results:
In our cohort, 34 patients had tumors in the sellar/suprasellar (S/SS) plus pineal gland (PG) regions and 15 in the S/SS plus basal ganglia/thalamus (BG/T) regions. The median follow-up period was 52 months (range, 10 to 134 months). Our survival analysis showed that patients treated with CSI (n=12) or whole-brain radiotherapy (WBRT; n=34) had comparable disease-free survival (DFS; p=0.540), but better DFS than those treated with focal radiotherapy (FR; n=3, p=0.016). All 81 patients from the literature had tumors in the S/SS+PG regions. Relapses were documented in 4/45 patients treated with FR, 2/17 treated with whole-ventricle irradiation, 0/4 treated with WBRT, and 1/15 treated with CSI. Survival analysis did not reveal DFS differences between the types of radiation field (p=0.785). HRQOL analysis (n=44) in our cohort found that, compared with S/SS+PG germinoma, patients with BG/T involvement had significantly lower scores in social and school domains. However, HRQOL difference between patients treated with CSI and those not treated with CSI was not significant.
Conclusion
In patients with non-metastatic bifocal germinoma, it is rational that CSI could be replaced by limited-field radiation. HRQOL in patients with BG/T involvement was poorer.