This study was designed to identify the relationship between perceived family support and quality of life in patients with liver cirrhosis. The subjects for this study were the 136 patients with liver cirrhosis that received hospital treatment in 1 general hospitals as Kwang-Ju City in Chonbuk and 3 general hospitals at Kwang-Ju City. The data were collected during the period from May 24 to August 2, 1997 by means of an interview utilized a structured questionnaire. Peceived family support was measured by the family support questionnaire that Kim, Eunu-Young(1996) used for her study about the relationships between perceived family support and self-care agency in adults with diabetes and the author of this study modified it instrument. Quality of life was measured by the quality of life instrument that Ro You-Ja(1998) developed by and analytical study of the quality of life the middle-aged in seoul and modified by the author of this study. The data were analyzed by descriptive statistics, t-test, ANOVA, Peraon's correlation, and Simple regression using the SPSS PC+ program. The results of this study were as follows: 1. relationship between perceived family support and quality of life in patients with liver cirrhosis revealed a significant correlation(r=0.581, p=.000). In addition, perceived family support in patients with liver cirrhosis provided predicted 32.37%(F=63.87, p=.000) of quality of life. 2. There were significant associations between perceived family support and religion(t=4.11, p=.000), occupation(f=4.40, p=.002), and the number of family(f=8.19, p=.000). There were significant associations between quality of life and occupation(f=7.52, p=.000), and economic state(f=3.30, p=.022) among general character. In conclusion, this study revealed that perceived family support in patients with liver cirrhosis may be an important factor that can improve their quality of life. Therefore, nurses must establish nursing plan included their family when nurse carry out nursing intervention and education for patients so that a patient promote quality of life by maintaining optimal well-being state.
Adult ; Education ; Gwangju ; Hospitals, General ; Humans ; Jeollabuk-do ; Liver Cirrhosis* ; Liver* ; Nursing ; Quality of Life* ; Self Care ; Seoul

No abstract available.
Biopsy

No abstract available.
Biopsy

No abstract available.
Calcification, Physiologic* ; Humans ; Infant, Newborn*

BACKGROUND: The apnea test is an essential component in the clinical determination of brain death, however it may incur a significant risk of complications such as hypotension, hypoxia and even cardiac arrest. We analyzed the risk factors associated with a failed apnea test during brain death assessment in order to predict and avoid these adverse events. METHODS: Medical records on apnea tests performed for brain-dead donors at our institution between January 2009 and January 2016 were retrospectively reviewed. Age, gender, etiology of brain death, use of catecholamines and results of arterial blood gas analysis (ABGA), systolic/diastolic blood pressure (SBP/DBP), mean arterial pressure and central venous pressure prior to apnea test initiation were collected as variables. A-a gradient and P(aO2)/F(iO2) were calculated for more precise assessment of the respiratory system. In total, 267 cases were divided into two groups based on those who completed the apnea test and those who failed the test. RESULTS: 13 cases failed the apnea test. Among them, seven cases failed due to severe hypotension (SBP < 60 mmHg) and the others failed due to refractory hypoxia. In terms of hemodynamic state, SBP was significantly higher in the completed test group than the failed group (126.5 ± 23.9 vs. 103 ± 15.2, respectively; p = 0.001). In ABGA, the completed test group showed significantly higher P(aO2)/F(iO2) (313.6 ± 229.8 vs. 141.5 ± 131.0, respectively; p = 0.008) and a lower A-a gradient (278.2 ± 209.5 vs. 506.2 ± 173.1, respectively; p = 0.000). In multivariable analysis, low SBP (p = 0.003) and high A-a gradient (p = 0.044) were independent risk factors associated with a failed apnea test. CONCLUSIONS: Although the unexpected adverse events during the apnea test for brain death determination do not occur frequently, they can be fatal. If a brain-dead patient has low SBP and a high A-a gradient, clinicians should pay more attention and prepare for potential complications prior to the apnea test.
Anoxia ; Apnea* ; Arterial Pressure ; Blood Gas Analysis ; Blood Pressure ; Brain Death* ; Brain* ; Catecholamines ; Causality ; Central Venous Pressure ; Heart Arrest ; Hemodynamics* ; Humans ; Hypotension ; Medical Records ; Respiratory System ; Retrospective Studies ; Risk Factors ; Tissue Donors

PURPOSE: Cerebral cortical dysplasias are one of the important causes for epileptic seizures and developmental disabilities in children, particularly in diffuse or bilateral cases. These developmental malformations are generally regarded as a group of neuronal migration disorders, however, the classification system and pathogenetic mechanisms of cortical dysplasias are not yet entirely clear. Even a novel entity, congenital bilateral perisylvian syndrome, characterized by speech delay, pseudobulbar Palsy, intractable seizures, and bilateral perisylvian abnormalities on imaging studies, have rather diverse figures on morphology and symptomatology than initially considered. We have studied the clinical features and correlations of clinical outcomes 3nd magnetic resonance imaging(MRI) findings of bilaterally involved cortical dysplasias. METHODS: 20 cases of bilateral cortical dyspalsias were grouped into three categories on the basis of MRI findings; centroparietal dysplasias(6 cases), diffuse dysplasias with (5) or without white matter lesions(4), and schizencephaly(5). EEGs, motor and language development, epilepsy, and outcomes were reviewed in each groups. RESULTS: Language delay(100%), motor developmental delay(94.7%), motor deficit(65%), epilepsy(40%) were the main reasons for their initial hospital visits. A meaningful word expression was possible at the mean age of 2 years and 2 months(1 to 4 years of age). Hypotonia and spastic motor paralysis were evident in all the cases of diffuse dysplasia with white matter lesions and the schizencephaly groups. All but one case of centroparietal dysplasia showed motor developmental delay. Epilepsies were developed in 8 cases at the mean age of 5 years and 5 months(2 months to 12 years of age) and the seizures were relatively well controlled with anticonvulsants. EEG findings were variable; normal, focal or diffuse abnormalities. High amplitude diffuse fast activities were only noted in the diffuse dysplasia group. CONCLUSION: The severity of neurological deficits and developmental delay had correlated to the size of cortical abnormalities. The epilepsies were relatively well controlled during childhood and the EEG finding of high amplitude diffuse fast activities was specific for the diffuse cortical dysplasias. Bilateral centroparietal dysplasias should be included on consideration of the causes for developmental aphasia.
Anticonvulsants ; Aphasia ; Child ; Classification ; Developmental Disabilities ; Electroencephalography ; Epilepsy ; Humans ; Language Development ; Language Development Disorders ; Magnetic Resonance Imaging* ; Malformations of Cortical Development* ; Muscle Hypotonia ; Muscle Spasticity ; Neuronal Migration Disorders ; Paralysis ; Pseudobulbar Palsy ; Seizures

No abstract availble

No abstract available.
Early Diagnosis* ; Ovarian Neoplasms*

BACKGROUND: Myocardial ischemia in human hypertension and in various animal models of hypertension may be due to abnormal maximal coronary vasodilator reserve and disturbaces of coronary vasomotion. The vascular reactivity defects in hypertension have been associated with the defective endothelium and sympathetic neural activation. However, such abnormalities in hypertension need to be elucidated. In the present study the effectsof cardiac ischemia reperfusion on coronary circulation, intramyocytic adenylates and purine nucleosides were examined in Langendorff-perfused Sprague Dawley rat (SD) and spontaneously hypertensive rat (SHR) hearts. Coronary venous and cardiac lactate and cardiac pyruvate were also measured. It should be noted that in the regulation of coronary flow the intrinsic flow autoregulation is highly variable due to coexisting metabolic flow control, and that natural coronary flow and cardiomyocytic energy state are normally reciprocally related in perfused heart. METHODS: For the Langendorff heart perfusion, bicarbonate perfusion buffer (pH 7.40+/-0.02,37degrees C) was equilibrated with 95% O2 : 5% CO2 and contained 5mM glucose (+5U/1 insulin) and 2mM pyruvate as energy-yielding substrates. Global hypoperfusion ischemia was induced by lowering coronary perfusion pressure of 100 to 40 cmH2O, followed by 20 min reperfusion. RESULTS: During the ischemia and reperfusion, metabolic acidosis and enhanced venous lactate output in SHR were observed with increases in coronary vascular resistance and myocardial oxygen consumption.In addition, coronary reactive hyperemia during reperfusion was depressed. Although ischemia-induced increase in combined adenosine plus inosine were abolished during prolonged reperfusion, SD still exhibited coronary vasodilation. The depressed reactive hyperemia in SHR was associated with decreases in cardiac adenosine triphosphate (ATP) pool and creatine phosphate/inorganic phosphate (CrP/Pi) ratio and an increase in cardiac lactate/pyruvate ratio. CONCLUSION: This abnormal vascular reactivity during ischemia and reperfusion in SHR may be in part due to an alteration in the cardiac energy state and hence to a mismatch between myocardial metabolic demand and supply.
Acidosis ; Adenosine ; Adenosine Triphosphate ; Animals ; Coronary Circulation ; Creatine ; Endothelium ; Glucose ; Heart* ; Homeostasis ; Humans ; Hyperemia ; Hypertension ; Inosine ; Ischemia ; Lactic Acid ; Models, Animal ; Myocardial Ischemia ; Oxygen ; Perfusion* ; Purine Nucleosides ; Pyruvic Acid ; Rats ; Rats, Inbred SHR* ; Reperfusion ; Vascular Resistance ; Vasodilation

The purpose of this study is to determine the impact of subjects perceived health condition and practiced health promotion life style to their satisfaction with their life. For this purpose, adults were surveyed, and thereby, data were collected to be analyzed. The data were collected during the period of August-September, 1997 and a total of 200 copies of the questionnaire were distributed and 162 copies were returned (return rate : 81%), Finally 57 copies were used for the analysis with 5 inappropriate ones dismissed. The data were analyzed using the SPSS PC+. The 157 subjects consisted of 65 males (41.4%) and 92 females (58.6%), and their average age was 49.39. It appeared that 59.9% of them were living with their spouse only, while 35.7% were living with children. On the other hand, 91.9% had spouses, and the majority of them(59.3) believed in Buddhisam, 35.7% of them graduated from middle school, while 31.2% finished high school. In economic terms, 25.5% of the respondents had an income of 1.01-1.50million won a month. It was disclosed that the demographic factors affecting subjects' health promotion life style were mostly type of the family, spouse, and educational background. The main demographic factor affecting their satisfaction with life was Age, while other variables showed no significant differences statistically. As a result of analyzing the correlation between perceived health condition, health promotion life styles and various factors related to satisfaction with life, it was shown that health promotion life style and perceived health condition were significantly correlated to each other statistically. And age, perceived health condition, health promotion life style, and satisfaction with life were significantly correlated to each other statistically. In conclusion health promotion life style and perceived health condition were identified as important variables in the life satisfaction of adult.
Adult* ; Child ; Demography ; Female ; Hand ; Health Promotion* ; Humans ; Life Style* ; Male ; Spouses ; Surveys and Questionnaires