【Objective】To observe the therapeutic effect of lifting-pulling-rotating and oblique-pulling manipulation in treating lumbar interverbral disc herniation(LIDH).【Methods】A multi-center prospective control trial was carried out in 181 LIDH patients.The patients were randomized into two groups: group A(N=90)was treated with lifting-pulling-rotating and oblique-pulling manipulation,and group B(N=91)with traditional massage manipulations.Scores of symptoms and signs were examined to evaluate the therapeutic effect after 2-week treatment and after 3-month,6-month and 12-month follow-up respectivel in the two groups.Meanwhile,the changes of myoelectrogram were compared after treatment in the two groups.【Results】Evaluated by the symptoms scores,77(85.6%)patients were cured,10(11.1%)markedly effective and 3(3.3%)ineffective in group A after 2-week treatment,and 45(45.4%),32(35.2%)and 14(15.4%)respectively in group B,the difference being significant(P0.05).【Conclusion】The effect of lifting-pulling-rotating and oblique-pulling manipulation is better than that of traditional massage manipulations for lumbar interverbral disc herniation.