【Objective】To observe the therapeutic effect of lifting-pulling-rotating and oblique-pulling manipulation in treating lumbar interverbral disc herniation(LIDH).【Methods】A multi-center prospective control trial was carried out in 181 LIDH patients.The patients were randomized into two groups: group A(N=90)was treated with lifting-pulling-rotating and oblique-pulling manipulation,and group B(N=91)with traditional massage manipulations.Scores of symptoms and signs were examined to evaluate the therapeutic effect after 2-week treatment and after 3-month,6-month and 12-month follow-up respectivel in the two groups.Meanwhile,the changes of myoelectrogram were compared after treatment in the two groups.【Results】Evaluated by the symptoms scores,77(85.6%)patients were cured,10(11.1%)markedly effective and 3(3.3%)ineffective in group A after 2-week treatment,and 45(45.4%),32(35.2%)and 14(15.4%)respectively in group B,the difference being significant(P0.05).【Conclusion】The effect of lifting-pulling-rotating and oblique-pulling manipulation is better than that of traditional massage manipulations for lumbar interverbral disc herniation.

Objective: To explore the impact of personalized early treatment appliances (ETA) on the relationship between dental and maxillofacial structures in patients with ClassⅡ malocclusion during the replacement phase, and to provide a basis for clinical treatment. Methods: This study was reviewed and approved by the Medical Ethics Committee, and informed consent was obtained from patients. From May 2023 to December 2023, 15 patients with Angle ClassⅡ malocclusion accompanied by mandibular retraction and anterior deep overjet during mixed dentition were enrolled in this study (8 males and 7 females; mean age 8.8 years). Each patient received a customized domestically manufactured ETA that was created based on dental arch dimensions, overjet severity, and occlusal relationships assessed from study models. Patients were instructed to wear the appliance for at least 2 hours during the day and throughout the night. The treatment duration was 6 months, at which time the changes in cephalometric data before treatment (T0) and after treatment (T1) were compared using Uceph software Results: The angle between sella, nasion and supramentale point B (SNB) of the patients increased significantly by (1.03 ± 1.74°) compared to before treatment (P = 0.039). The angle between subspinale point A and supramentale point B (ANB), the distance between point A and point B on the FH plane (wits value), the overjet, and the overbite decreased by (0.47 ± 0.61°), (2.48 ± 2.11) mm, (2.48 ± 3.42) mm, and (0.79 ± 1.40) mm, respectively, compared to before treatment, and the differences were statistically significant (P<0.05). The angle between sella, nasion and subspinale point A (SNA), the angle between the FH and MP planes (FMA), the angle between the long axis of the L1 and MP plane (IMPA), the angle between the MP plane and SN plane (MP-SN), the distance from S to Go divided by the distance from N to Me (S-Go/N-Me), and the distance of the FH plane perpendicular from G point to the Pog point (G Vert Pog) increased compared to before treatment, while the angle between the SGn and FH planes (Y-axis) and the angle between the long axis of the L1 and FH plane (FMIA) decreased compared to before treatment, but there was no statistical difference (P>0.05). Conclusion Personalized, customized ETA orthodontic appliances can effectively improve the sagittal and vertical relationships between the maxilla and mandible in patients with ClassⅡ malocclusion.