Objective To explore the influences of Bushen Zhuanggu Granule (BZG)on contents of sexual hormones and metabolism of calcium and phosphorous in early menopausal women.Methods One hundred and Twenty-two early menopausal women were allocated to two groups:Group A was treated with BZG and Group B with nylestriol.Serum contents of sexual hormones and indexes of calcium and phosphorous metabolism were observed before and after treatment.Results After six months of treatment,the contents of serum estradiol(E 2)and alkaline phosphatase(ALP)were increased and the ratio of urine calcium and creatinine(Ca/Cr)decreased(P 0.05).The contents of follicle stimulating hormone(FSH)and luternizing hormone(LH)were increased in Group A as compared with Group B(P