The purpose of this study was to examine the effect of two kinds of neck muscle training on the isometric cervical extension strength (ICES) and cross-sectional area (CSA) of the neck extensor muscles.The subjects which were examined consisted of 22 male college judo athletes. Each was assigned to one of three groups: shrug and upright rowing training (SU); shrug, upright rowing and dynamic neck muscle training (COM); and control (CONT). The SU and COM groups trained 3 days per week for 9 weeks. The ICES and CSA of the neck muscles were measured before and after muscle training.The ICES of the COM group showed a significant increase after training. For the CSA, although a significant increase was only found in a superficial area of the neck extensor muscles in the SU group, the COM group showed significant increases in all areas.This study determined that combined neck muscle training is effective for developing the neck extensor muscles.

The purpose of this study was to examine the effects of dynamic neck muscle training using a cervical extension machine (CEM) on isometric cervical extension strength (ICES) and a cross-sectional area of neck extensor muscles.Subjects were 18 male college judo athletes divided into a control group (n=10) and training group (n=8), respectively. In the training group, dynamic neck muscle training was performed for a 6 week training period, followed by a 10 week training period. There was a detraining period of 12 weeks between the first training period and the second. The ICES was measured at eight angles using a CEM, and the neck muscle cross-sectional area was determined using magnetic resonance imaging.The ICES and cross-sectional area of neck extensor muscles in the training group showed significant increases after the second training period. In particular, the increase in the cross-sectional area was greater in the deepest layer of the neck extensor muscles (rotator, multifidus and semispinaris cervicis muscles) than in the superficial layer (trapezius muscle). In the control group, no significant changes in ICES or cross-sectional area were observed.In conclusion, it was shown that dynamic neck muscle training using a CEM was effective in developing both ICES and the cross-sectional area of neck extensor muscles, especially in the deepest layer.

This report documents the case of a male in his sixties who developed multiple lymph node metastases after receiving external beam radiation therapy and androgen deprivation therapy for locally advanced prostate cancer. Agglomerated pelvic lymph node metastases caused lower extremity lymphedema, however the patient was administered systemic chemotherapy with docetaxel. Because surrounding normal tissue was already irradiated by the prior therapy, radiation against pelvic lymph nodes by LINAC was in danger of exceeding tolerance dose. Therefore, the patient received stereotactic radiosurgery by cyberknife that has a high degree of accuracy in target identification and localization for pelvic lymph node metastases. The lower extremity lymphedema was declined and his activity of daily living was recovered without obvious side effects. Here we report the case of successfully controlled lymphedema by palliative cyberknife therapy.

Due to the widespread acceptance of gastric and esophageal endoscopic submucosal dissections (ESDs), the number of medical facilities that perform colorectal ESDs has grown and the effectiveness of colorectal ESD has been increasingly reported in recent years. The clinical indications for colorectal ESD at the National Cancer Center Hospital, Tokyo, Japan include laterally spreading tumor (LST) nongranular type lesions >20 mm and LST granular type lesions >30 mm. In addition, 0-IIc lesions >20 mm, intramucosal tumors with nonlifting signs and large sessile lesions, all of which are difficult to resect en bloc by conventional endoscopic mucosal resection (EMR), represent potential candidates for colorectal ESD. Rectal carcinoid tumors less than 1 cm in diameter can be treated simply, safely, and effectively by endoscopic submucosal resection using a ligation device and are therefore not indications for ESD. The en bloc resection rate was 90%, and the curative resection rate was 87% for 806 ESDs. The median procedure time was 60 minutes, and the mean size for resected specimens was 40 mm (range, 15 to 150 mm). Perforations occurred in 23 (2.8%) cases, and postoperative bleeding occurred in 15 (1.9%) cases, but only two perforation cases required emergency surgery (0.25%). ESD was an effective procedure for treating colorectal tumors that are difficult to resect en bloc by conventional EMR. ESD resulted in a higher en bloc resection rate as well as decreased invasiveness in comparison to surgery. Based on the excellent clinical results of colorectal ESDs in Japan, the Japanese healthcare insurance system has approved colorectal ESD for coverage.
Asian Continental Ancestry Group ; Carcinoid Tumor ; Colorectal Neoplasms ; Delivery of Health Care ; Emergencies ; Hemorrhage ; Humans ; Insurance ; Japan ; Ligation ; Tokyo

Background/Aims: Immune checkpoint blockade has recently been reported to be effective in treating microsatellite instability (MSI)-high tumors. Therefore, sufficient sampling of histological specimens is necessary in cases of unresectable pancreatic cancer (UR-PC). This multicenter study investigated the efficacy of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) using a Franseen needle for MSI evaluation in patients with UR-PC. Methods: A total of 89 patients with UR-PC who underwent endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or EUS-FNB using 22-G needles at three hospitals in Japan (2018–2021) were enrolled. Fifty-six of these patients (FNB 23 and FNA 33) were followed up or evaluated for MSI. Patient characteristics, UR-PC data, and procedural outcomes were compared between patients who underwent EUS-FNB and those who underwent EUS-FNA. Results: No significant difference in terms of sufficient tissue acquisition for histology was observed between patients who underwent EUS-FNB and those who underwent EUS-FNA. MSI evaluation was possible significantly more with tissue samples obtained using EUS-FNB than with tissue samples obtained using EUS-FNA (82.6% [19/23] vs. 45.5% [15/33], respectively; p<0.01). In the multivariate analysis, EUS-FNB was the only significant factor influencing the possibility of MSI evaluation. Conclusions EUS-FNB using a Franseen needle is desirable for ensuring sufficient tissue acquisition for MSI evaluation.