With the spread of a novel H1N1 strain of influenza A around the world, the World Health Organization declared that the situation had entered the pandemic phase. In Japan, it had a major social impact, causing a great hit to the national economy. And there is every likelihood that the H1N1 influenza is going to break out a lot of people on the staff of the agricultural cooperatives in Aichi Prefecture, seriously affecting the activities of agricultural cooperatives too. Based on the amount of damage from the flu presumed by the Japanese government and various kinds of statistical material, we worked out how much the flu would cost the agricultural co-ops in the prefecture by infecting their employees and involved their family. At an absence rate of 20%, the lowest rate presupposed by the government, our calculation showed that the extra costs would amount to 740 million yen altogether. If the rete of abscense from work was given 40%, the largest estimate by the government, the costs rocketed to highly 1.48 billion yen. A check on the situation of individual co-ops revealed that some of the co-ops would burden an extra cost of well over 100 million yen. From these findings, we concluded that to minimize the effects of the flu appropriate, effective countermeasures have to be taken after sufficient information about the novel influenza virus was collected and analyzed carefully.

Although introduced to Japan as a health food, Huaier granule emerged with abundant evidence, both from fundamental and clinical researches, and is being prescribed clinically in China, since it was originally developed as a new pharmaceutical. Huaier granule has a wide range of application and this review narrow down to the effects of it to hepatocellular carcinoma, the most reported one.

The supinator muscle originates from the annular ligament of the radius, and the muscle fibers and ligament take a similar winding course. Likewise, the coccygeus muscle and the sacrospinous ligament are attached together, and show a similar fiber orientation. During dissection of adult cadavers for our educational curriculum, we had the impression that these ligaments grow in combination with degeneration of parts of the muscles. In histological sections of 25 human fetuses at 10-32 weeks of gestation, we found that the proximal parts of the supinator muscle were embedded in collagenous tissue when the developing annular ligament of the radius joined the thick intermuscular connecting band extending between the extensor carpi radialis and anconeus muscles at 18-22 weeks of gestation, and the anterior parts of the coccygeus muscle were surrounded by collagenous tissue when the intramuscular tendon became the sacrospinous ligament at 28-32 weeks. Parts of these two muscles each seemed to provide a mold for the ligament, and finally became involved with it. This may be the first report to indicate that a growing ligament has potential to injure parts of the "mother muscle," and that this process may be involved in the initial development of the ligament.
Adult ; Cadaver ; Collagen ; Curriculum ; Fetus ; Fungi ; Humans ; Ligaments ; Muscles ; Orientation ; Pregnancy ; Radius ; Tendons ; Wind

Huaier granule, which is clinically used in Japan as a health food, is originally a traditional Chinese medicine for immune dysfunction, such as cancer, in China. Huaier guanule emerged with abundant evidence, and is being prescribed to hepatocellular carcinoma, breast cancer, lung cancer, gastric cancer, et al. as indications in China. This review focused on the clinical evidence of Huaier guanule associated to breast cancer.