1.Centralized Medical Equipment Management System in Our Hospital
Ai NAKAIZUMI ; Yoshihiro HONDA ; Takeshi NAKANE ; Naoki YAMADA ; Yukio MITANI ; Takaaki SUZUE
Journal of the Japanese Association of Rural Medicine 2003;52(4):733-736
Before we moved into the present hospital building in October 2000, we took the opportunity to thoroughly review our medical equipment management system and developed a new centralized management system. With the introduction of the new system, we have made a complete list [an inventory] of medical equipment on hand from small-size instruments to large-scale machinery. We have now become able to grasp the frequency of use of ME, the cause of mechanical trouble, the cost of repairing and so forth. In the future, this system will be further improved so as to enable us to incorporate a labor-saving procedure for equipment lending into the system, share information with other departments, and work out a net working rate and repair rate to make purchasing or disposal plans.Medical care and health services of today cannot be provided without use of modern medical equipment. Under the circumstances, the prevention of accidents and grasp of the optimum amount of machinery and equipment are important. At the same time, the reduction of cost by adequate maintenance work is essential. We think that our centralized equipment management system will work effectively and serve the purpose.
medical equipment
;
Equipment used
;
Work
;
Hospitals
;
Management
2.Saikokaryukotsuboreito Could be Effective Even if Shakanzoto is Ineffective for Paroxysmal Atrial Fibrillation with Strong Palpitation after Cardiac Surgery
Koji KAWAGO ; Yukiyo YOSHIDA ; Satoru SHIRAIWA ; Yoshihiro HONDA ; Kenji SAKAKIBARA ; Shigeaki KAGA ; Hiroyuki NAKAJIMA
Kampo Medicine 2021;72(1):27-33
Paroxysmal atrial fibrillation (pAf) is an arrhythmia that often occurs in the elderly. The quality of life often declines due to severe palpitations caused by pAf. We present a case of recurrent pAf that occurred on postoperative day 2 of coronary artery bypass grafting and pulmonary vein isolation for unstable angina pectoris and pAf. The patient was a 62-year-old man who complained of palpitations, which was consistent with pAf on the monitor ECG. During hospitalization, the patient was constantly wearing an ECG monitor. During pAf, the heart rate was around 120 bpm, and pAf could continue for up to and beyond 24 hours. Paroxysmal atrial fibrillation with strong palpitations was observed every day, even after starting beta-blockers and anticoagulants. After discharge, a Japanese Kampo medicine called shakanzoto was taken for a month, but there was no improvement. After that, it was changed to another Japanese Kampo medicine called saikokaryukotsuboreito, because abdominal examination revealed kyokyokuman (hypochondriac discomfort and distension (resistance)) and saiboki (brisk pulsation in the para-umbilical region). Palpitations quickly improved dramatically. It was speculated that not only palpitations but also pAf had been improved.
3.A Case of Fungal Mycotic Abdominal Aortic Aneurysm with Candida albicans Sepsis
Yoshihiro HONDA ; Yukiyo YOSHIDA ; Koji KAWAGO ; Satoru SHIRAIWA ; Kenji SAKAKIBARA ; Shigeaki KAGA ; Hiroyuki NAKAJIMA
Japanese Journal of Cardiovascular Surgery 2020;49(6):375-379
Background : Fungal mycotic aneurysm is rare ; however, special care and treatment are required for the deep fungal infection itself. Case : The patient was a 69-year-old man with a history of sepsis due to Candida albicans. He suffered from back pain and moderate fever. CT revealed saccular-form aneurysm at the infrarenal abdominal aorta. After emergent in situ bifurcated graft replacement of the infected aneurysm, antifungal treatment was attempted in reference to the antifungal drug sensitivity of C. albicans from intraoperative cultures and findings of fungal endophthalmitis in an ophthalmic examination. After an uneventful acute course, follow up CT images after 12 months postoperatively revealed pseudoaneurysm formation proximal to the site of graft anastomosis. Reoperation was planned with a trans-thoracic and transabdominal approach because of concerns about thoracoabdominal aortic infection. However, the reoperation displayed only inflammatory tissue around the graft and aortic tissue. Removal of the previous graft and reconstruction of the bilateral renal artery, and the pararenal abdominal aorta to the bilateral common iliac artery was performed. Intraoperative tissue cultures revealed no evidence of microorganisms. He returned home with oral antifungal treatment and is doing well at 8 months after the reoperation. Conclusions : Management of fungal mycotic aneurysms requires both surgical treatment and antifungal treatment. Antifungal agents should be selected based on the results of a susceptibility test and after examinations for metastatic comorbidities.
4.Successful Repair of Traumatic Tricuspid Regurgitation
Satoru SHIRAIWA ; Yoshihiro HONDA ; Kenji SAKAKIBARA ; Masatake KATSU ; Shigeaki KAGA ; Shoji SUZUKI ; Hiroyuki NAKAJIMA
Japanese Journal of Cardiovascular Surgery 2018;47(3):128-132
A 62-year-old man was referred to our hospital because of dyspnea. Electrocardiogram showed chronic atrial fibrillation and echocardiogram revealed severe tricuspid regurgitation. His history included a motorbike accident at age 17, and a heart murmur was pointed out in the following year. He developed paroxysmal atrial fibrillation when he was 45 years old. Heart failure was not controlled by medication and tricuspid valve repair was indicated. At surgery, the anterior leaflet of tricuspid valve was widely prolapsed due to chordal rupture. We performed chordal reconstruction with 4 expanded polytetrafluoroethylene (CV-5®) sutures, and ring annuloplasty. Furthermore, a small fenestration at the tricuspid annulus was noticed and was closed with a direct suture. The biatrial modified Maze procedure was performed subsequently. The patient is doing well without TR recurrence, and restored sinus rhythm is maintained. We report successful repair of traumatic tricuspid regurgitation.
5.RANKL+ senescent cells under mechanical stress: a therapeutic target for orthodontic root resorption using senolytics.
Yue ZHOU ; Aki NISHIURA ; Hidetoshi MORIKUNI ; Wenqi DENG ; Toru TSUJIBAYASHI ; Yoshihiro MOMOTA ; Yuki AZETSU ; Masamichi TAKAMI ; Yoshitomo HONDA ; Naoyuki MATSUMOTO
International Journal of Oral Science 2023;15(1):20-20
In dentistry, orthodontic root resorption is a long-lasting issue with no effective treatment strategy, and its mechanisms, especially those related to senescent cells, remain largely unknown. Here, we used an orthodontic intrusion tooth movement model with an L-loop in rats to demonstrate that mechanical stress-induced senescent cells aggravate apical root resorption, which was prevented by administering senolytics (a dasatinib and quercetin cocktail). Our results indicated that cementoblasts and periodontal ligament cells underwent cellular senescence (p21+ or p16+) and strongly expressed receptor activator of nuclear factor-kappa B (RANKL) from day three, subsequently inducing tartrate-resistant acid phosphatase (TRAP)-positive odontoclasts and provoking apical root resorption. More p21+ senescent cells expressed RANKL than p16+ senescent cells. We observed only minor changes in the number of RANKL+ non-senescent cells, whereas RANKL+ senescent cells markedly increased from day seven. Intriguingly, we also found cathepsin K+p21+p16+ cells in the root resorption fossa, suggesting senescent odontoclasts. Oral administration of dasatinib and quercetin markedly reduced these senescent cells and TRAP+ cells, eventually alleviating root resorption. Altogether, these results unveil those aberrant stimuli in orthodontic intrusive tooth movement induced RANKL+ early senescent cells, which have a pivotal role in odontoclastogenesis and subsequent root resorption. These findings offer a new therapeutic target to prevent root resorption during orthodontic tooth movement.
Rats
;
Animals
;
Root Resorption/prevention & control*
;
Senotherapeutics
;
Stress, Mechanical
;
Dasatinib/pharmacology*
;
Quercetin/pharmacology*
;
Osteoclasts
;
Tooth Movement Techniques
;
Periodontal Ligament
;
RANK Ligand