1.Analysis on the Linguistic Ethical Characteristics of Medical Solace Words
Qian WANG ; Yongxiang YAN ; Yu FU
Chinese Medical Ethics 1994;0(05):-
Medical Solace Words are a kind of working language used by medical staff who tend to offer solace and encouragement to patients on purpose of medical treatment,and it is a kind of oral language frequently applied by medical staff in the new medical mode.Medical solace aims at decreasing and eliminating patients' negative emotions and improving their mood so as to establish a harmonious relationship between doctors and patients,and make the treatment smooth as well.This article analyzes medical solace words from the perspective of linguistic pragmatics,revealing that for the concealment and complexity of the expressing context for medical words,and the unique programmatic rules of medical language,medical staff should pay much attention to the language hierarchy and grasp the explanatory principle and the guiding principle of medical solace language to achieve the targeted effects of medical solace.
2.An Sociological Analysis of the External Forms of Doctor-Patient Conflict in Present China
Qian WANG ; Yongxiang YAN ; Juhua MA ; Xingbing LIU
Chinese Medical Ethics 1994;0(06):-
Doctor-patient conflict is a social problem in the present phase of medical development in China that has come into being due to the huge gap between the doctor's and the patient's understanding and requirement concerning their roles,rights,obligations and interest.It results from intersection and collision of various social factors.From the sociological perspective,it has been found that the main causes of such a problem include: the limited health resources and its uneven distribution;the doctor as the monopoly of medical resources;the doctor and the patient both as seekers of maximal self-interest.According to the conflict theory in sociology,doctor-patient conflict can be classified,in terms of form,degree,and goal of conflict,into direct and indirect conflict,violent and non-violent conflict,and reality and non-reality conflict respectively.Indirect conflict and non-reality conflict deserve special attention because of their hiddenness,latency,and deep influence upon doctor-patient relationship.
3.Researches in examination reform of physiology
Yongxiang ZHU ; Zanying XIAO ; Qian WANG ; Wei YU ; Ying NAN
Chinese Journal of Medical Education Research 2005;0(06):-
Toresolve the problems in current physiologyexam,this paper proposed the measures in examination reform of physiology,which would provide reference for better training innovative medical personnel with a good overall quality to meet the needs of society.
4.Effect of Chaihushugansan combined with fluoxetine on IL-6, IL-1β, TNF-α in postpartum depression
Yue ZHAO ; Yongxiang LI ; Keng LING ; Yaqin QIAN ; Xiaoyan ZHANG
Chinese Journal of Biochemical Pharmaceutics 2016;36(4):127-129
Objective To observe the effect of Chaihushugansan combined with fluoxetine on interleukin -6 ( IL-6 ) , interleukin -1β( IL-1β) , tumor necrosis factor ( TNF-α) in the treatment of patients with postpartum depression.Methods 83 patients from November 2013 to July 2015 in Jiaxing Maternity and Child Health Care Hospital were randomly divided into 41 patients of observation group and 42 patients of control group.The control group were treated with fluoxetine treatment, the obsercation group received Chaihushugansan on the basis of control group.The Hamilton depression scale (HAMD) and Hamilton anxiety scale (HAMA),IL-6, IL-1β, TNF-α, high-sensitivity C-reactive protein (hs-CRP) and adverse reactions were followed up and recorded.Results The HAMD and HAMA score in observation group post-treatment were (8.31 ±2.05,9.03 ±2.08)points, which were lower than (13.96 ±2.16, 13.61 ±2.14) points in control group (P<0.05).The serum IL-6 and IL-1βlevels in observation group post-treatment were (6.59 ±3.20,5.01 ±2.83)pg/mL, which were lower than (10.64 ±3.86,9.31 ±3.42)pg/mL in control group (P<0.05).The serum TNF-αand hs-CRP levels in observation group post-treatment were ( 9.16 ±2.01 ) pg/mL, ( 3.62 ±1.06 ) mg/L, which were lower than ( 12.30 ±2.37 ) pg/mL, (5.29 ±1.14)mg/L in control group (P<0.05).The total adverse reaction rate in observation group was 7.32%, significantly lower than 23.81% in control group ( P <0.05 ) .Conclusion Chaihushugansan combined with fluoxetine has a good therapeutic effect in the treatment of postpartum depression, could significantly reduce the IL-6, IL-1β, TNF-α levels, with fewer side effects, it is better than fluoxetine alone.
5.The Selection and Application of Examination Paper Analysis Indexes
Yongxiang ZHU ; Zanying XIAO ; Danqin XIAO ; Juanxia ZHU ; Qian WANG ; Wei YU
Chinese Journal of Medical Education Research 2003;0(03):-
Examination paper analysis is an important job in examination management.It includes qualificative analysis and quantitative analysis,which are connective and complementary.This essay discusses the selection and application of examination paper analysis indexes.
6.The cranial MRI appearance of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy in a family
Jinping ZHANG ; Binglian SUN ; Yongqiang YU ; Hua PAN ; Yongxiang TANG ; Zhen QIAN ; Ping GAO ; Feng LIU ; Huifen LI
Chinese Journal of Radiology 2008;42(2):167-171
ObjectiveTo recognize the cranial MRI appearance in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy(CADASIL). MethodsFive patients with CADASIL from two generations in a family underwent routine MRI and MRA examinations.Three patients with CADASIL were confirmed by the Notch3 genetic testing and the vascular pathological Resultsand one was diagnosed on basis of MR and clinical manifestations. The imaging data from 4 patients with CADASIL were analyzed.ResultsFour cases achieved preliminary diagnosis of CADASIL and one was excluded by MRI.In 4 patients with CADASIL,bilateral symmetrical,confluent white matter lesions in the subcortical and Deriventricular regions were seen frequently in the temporal,frontal and parietal lobes,but the occipital lobes were less involved.These lesions appeared as long T1 and long T2 signal.O'Sul]ivan sign was shown in all cases and subcortical lacunar lesions was seen in 2 cases. In the centrum semiovale,well-defined,round or oval cystic infarcts(black holes)were demonstrated in 3 cases and multiple tiny round enlarged perivascular spaces(pepperpot appearance)in all cases.The corpus callosum was involved in all cases,and it was evidently atrophic in 2 cases.The anterior part of internal capsule and external capsule were were present in the basal ganglia and brainstem. Only one case revealed a small infarct in the right cerebellum. Four Datients shared mild or moderate atrophy of brainstem, cerebellum and cerebrum. No marked abnorillalitv of large vessels was seen in all cerebral MRA. ConclusionsThe cranial MRI appearance in CADASIL shows some characteristics.MRI may give some infotznation in the preliminary diagnosis or exclusion of CADASIL.
7.Characteristics of posterior corneal astigmatism and aberration in cataract patients with high myopia
Qinghe JING ; Yating TANG ; Dongjin QIAN ; Yi LU ; Yongxiang JIANG
Chinese Journal of Experimental Ophthalmology 2018;36(5):360-367
Objective This study was to investigate the characteristics of posterior corneal astigmatism (PCA) and aberration in cataract patients with high myopia.Methods A retrospective study was designed.Two hundred and eighty-two eligible eyes of 190 cataract patients were enrolled in Eye and ENT Hospital of Fudan University from September to December,2014.The eyes were classified into two groups according to axial length (AL):high myopia group with 139 eyes (AL≥26 mm) and control group with 143 eyes (AL was 20 to 25 mm).The mean keratometric mid-radius of curvature (Km),corneal central thickness (CCT),astigmatism and aberrations were measured by the rotating Scheimpflug System (Pentacam),and the AL were measured by the partial coherence interferometry (IOL Master).This study followed the Helsinki declaration,and was approved by the Ethic Committee of Eye and ENT Hospital,Fudan University.Informed consent was signed from each patient.Results In high myopia group,the mean PCA was 0.3 D (range 0 ~ 0.9 D) and 92.8% eyes had PCA values <0.5 D.The steep corneal meridian was aligned vertically (60°~ 120°) in 87.1% eyes for the posterior corneal surface.There was no significant difference in PCA between the high myopia group and the control group (P =0.797).Significant positive linear correlations was found between PCA and anterior corneal astigmatism (ACA),PCA and anterior corneal root mean square (RMS),PCA and anterior lower-order RMS,PCA and posterior corneal RMS,PCA and posterior high-order RMS,PCA and posterior lower-order RMS (r =0.235,P =0.005;r =0.217,P =0.010;r =0.229,P =0.007;r =0.395,P =0.000;r =0.243,P =0.004;r =0.384,P =0.000).Compared with total corneal astigmatism (TCA),anterior corneal measurements overestimated with-the-rule astigmatism (WTR) by a mean of (0.27 ± 0.18) D in 65.67% eyes,underestimated against-the-rule astigmatism (ATR) by (0.27 ± 0.18) D in 88.10% eyes and underestimated oblique astigmatism (Obl) by (0.22 ± 0.10) D in 63.33% eyes.Compared with total corneal aberrations,anterior corneal aberrations measurements overestimated by (0.275 ±0.176) μm in 87.05 % eyes,and the anterior corneal astigmatism types had no effect on the result.Conclusions In high myopia group,92.8% eyes had PCA values <0.5 D and the main astigmatism type in posterior corneal surface was ATR.The posterior corneal astigmatism and aberration were needed to consider in choosing intraocular lens (IOL) before cataract surgery.
8.Expression and its significance of eosinophil major basic protein in chronic rhinosinusitis.
Jing HOU ; Bing ZHOU ; Luo ZHANG ; Yunchuan LI ; Ming LIU ; Yongxiang WEI ; Qian HUANG ; Yang WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2008;22(10):454-455
OBJECTIVE:
To evaluate the expression of eosinophil major basic protein (MBP) in chronic rhinosinusitis (CRS) and discuss the role of MBP in the pathogenesis in CRS.
METHOD:
Thirty-eight nasal mucus obtained from CRS patients were used to detect the expression of MBP by Elisa assay. Thirty nasal mucus samples from health people were used as control.
RESULT:
The expression of MBP of nasal mucus obtained from CRS patients was obviously higher than that of nasal mucus obtained from control. There was significant statistical difference (P < 0.01).
CONCLUSION
MBP was involved in the formation of CRS.
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9.Clinical study of emerging sternal rigid plate:a randomized controlled double-center trial
Bin WANG ; Dapu HE ; Yongxiang QIAN ; Bing WEI ; Dongmei DI ; Yaoguang FENG ; Xianghong ZHAN ; Chaozhong LONG ; Rui ZHOU ; Xiaoying LIANG ; Zhang MO
Chinese Journal of Thoracic and Cardiovascular Surgery 2017;33(12):743-746
Objective To evaluate the security and effectiveness of emerging sternal rigid plate by comparing with wires closure. Methods 60 patients who undergoing median sternotomy from two centers were enrolled in this study, 30 received wire cerclage( control group) and the other 30 received rigid plate fixation( experimental group) . Patients' sternal were closed with wires or rigid plates, and the painness, sternal union and status of wires or rigid plates were followed up and assessed one week, three months and six months after procedures. Results All patients survived and were followed up. 117 rigid plates were implanted. There was no significant difference in pre-operative data, post-operative painness, sternal union and status of wires and plates between control and experimental group. No patient reached the standard of clinical sternal union one week post-operation, but all patients reached the standard of clinical sternal six months post-operation. One patient in control group suffered sternal nonunion, movement and wound infection after sternotomy. Conclusion Compared to wire closure, sternal closure with rigid plates is the same safe and effective.
10.Clinical value of preoperative viable myocardium and postoperative left ventricular mechanical dyssynchrony for prognosis evaluation in patients undergoing coronary artery bypass graft
Feifei ZHANG ; Jianfeng WANG ; Xiaoliang SHAO ; Yongxiang QIAN ; Wei YANG ; Wenchong XIN ; Rong NIU ; Xiaoxia LI ; Hui YAN ; Mei XU ; Zhen ZHU ; Xiaosong WANG ; Yuetao WANG
Chinese Journal of Nuclear Medicine and Molecular Imaging 2018;38(7):466-470
Objective To investigate the predictive value of preoperative viable myocardium and postoperative left ventricular mechanical dyssynchrony (LVMD) for adverse cardiovascular events(ACE) after coronary artery bypass graft (CABG) in patients with coronary artery disease (CAD) using myocardial perfusion imaging (MPI).Methods From September 2012 to March 2016,49 patients (44 males,5 females,average age:(64±8) years) with CAD were prospectively recruited.All patients underwent 99Tcmmethoxyisobutylisonitrile (MIBI) SPECT gated MPI (GMPI) and 18F-fluorodeoxyglucose (FDG) PET myocardial metabolic imaging to assess myocardial viability preoperatively.GMPI was repeated 4-6 months after CABG to record postoperative LVMD.Phase analysis was used to measure bandwidth (BW) and standard deviation (SD).Regular follow-up was performed,and ACE were taken as the end point.Cox proportional hazard model,Kaplan-Meier method and log-rank test were used to analyze the data.Results The mean duration of follow-up was (3.82±0.80) years,and ACE were present after CABG in 17 CAD patients (34.7%,17/49).Cox multi-analysis revealed that the number of preoperative viable segments (hazard ratio (HR)=0.208,95% CI:0.068-0.642) and postoperative BW (HR=1.245,95% CI:1.099-1.411)were independent influencing factors of ACE in CAD patients after CABG (both P<0.01).Kaplan-Meier survival analysis showed that the incidence of ACE in patients with < 3 viable segments was significantly higher than those with ≥ 3 viable segments (57.1% (12/21) vs 17.9% (5/28);x2 =21.023,P<0.01).The incidence of ACE was significantly higher in the postoperative BW≥98° group than that in the postoperative BW<98° group (14/19 vs 10% (3/30);x2 =38.395,P<0.01).Conclusions Less preoperative viable segments and severe postoperative LVMD are independent risk factors of ACE after CABG in CAD patients.Postoperative LVMD in CAD patients undergoing CABG may have important clinical value in the riskrestratification and prognosis evaluation.