Tumor markers refer to the specific substances that exist in tumor cells themselves or are secreted by tumor cells. They can reflect the existence and growth of the tumor. The serum tumor biomarkers have been widely applied in tumor detection,but the detection of these markers is based on the tumor antigens,and thus has many inadequacies in tumor screening and diagnosis. In this paper,we reviewed autoantibodies as tumor biomarkers against self-antigens in vivo. This method is to examine the tumor autoantibodies by using the tumor antigens,and its specificity and sensitivity are superior to the traditional examination methods. Using autoantibodies to detect tumors would provide a new method for tumor screening and diagnosis.

Objective To analyses the efficacy of treatment of blood vessels wounded with firearm in limbs by microsurgical technique Methods From March 1979 to October 2000,560 cases whose blood vessels were wounded with firearm in limbs were repaired by microsurgical technique Results Five hundred and twenty cases were good,17 cases were disable,15 cases were amputated limds,and 8 cases died Conclusions The majority of blood vessels wounded with firearm in limbs can be obtained good results being repaired by microsurgical technique

ObjectiveTo observe the effects of medical membrane of combination of the traditional Chinese medicine with the western medicine on white lesion of the vulva.Methods141 cases of white lesion of the vulva were put on vulvar pathological area with the medical membrane, twice a day.ResultsThe total effective rate was 98.5%.ConclusionThe effect of medical membrane of combining the traditional Chinese medicine with the western medicine is very satisfying.

This article elaborated the importance of strengthening the Chinese herbal pieces industry management from aspects such as the strengthening of process management, production and marketing integration of herbal pieces, self-discipline of Chinese herbal pieces industry, high price for high quality, scientific research management and construction of laws and regulations. It explored key issues of Chinese herbal pieces from aspects such as industry management, stabilization of herbal pieces quality and clinical efficacy guarantee. It suggested that the industry management of Chinese herbal pieces should be strengthened with stable quality to ensure the clinical efficacy.

In this paper, based on the scientific research of TCM for many years and from the front-line point of view, the author explored the mainly common problems which had been existed in the TCM research, such as the establishment of the quality standard, the research of innovative drugs, the research ideas differentia between TCM and the natural drugs, the improvement of the research management model and other issues.

0 05), and the adverse reaction for sulthiame was mild and no necessary to cure.Conclusion It is effective and safe in the treatment for GTCS with sulthiame.

In this paper, the author proposed the development direction and study task for processing subject. Its development direction were study of scientific research method and establishment of technological platform for processing-patterns for the scientific research and production combination (enterprise as the mainstay). And its main task will be located at the inheritance of the traditional Chinese medicine pharmaceutical technology, the protection of processing culture as the non-material heritage, and the development of processing as a modern subject.

Objective To study the location and level of relaxin receptor in placenta tissues of preeclampsia and normal pregnancy,and the relationship of relaxin receptor with pre-eclampsia.Methods Twenty-six placenta tissue samples from pregnant women with severe preeclampsia(study group),and 20samples from normal pregnancies(control group)were obtained.We detected the expression of relaxin receptor by immunohistochemistry and the expression of relaxin receptor mRNA by RT-PCR.Results In the placenta of control and preeclampsia groups,the leucine-rich repeat-containing G protein-coupled receptor(LGR7)was positively expressed.Relaxin receptor was located in the membrane of trophoblast cells.There were both strong signals on cytotrophoblastic cells and syneytiotrophoblast.The level of relaxin receptor in the control group was 0.912 ±0.003.and 0.625±0.037 in the preeclampsia group.Thedifference between the two groups was obvious(P＜0.01).In the control group,the level of relaxin receptor mRNA was 0.776±0.021;in the preeclampsia group,it was 0.393±0.075.The difference was obvious(P＜0.01).Conclusion Decrease in the expression of relaxin receptor at placenta is related with the occurrence and development of preeclampsia.

Objective　To review the recent progress in the treatment of wrist disorder by limited intercarpal arthrodesis and the related experimental study. Methods　Recent original articles related to limited intercarpal arthrodesis, including clinical practice and experimental study, were extensively retrieved and carefully analyzed. Results　Limited intercarpal arthrodesis could relieve pain and stabilize the wrist joint with partial motion. Conclusion　 With suitable indication and well selected operation approach, the limited intercarpal arthrodesis should be the optimal surgical intervention than total carpal athrodesis in the treatment of wrist disorder.

Objective To detect the levels of procalcitonin,blood routine,C-reactive protein of children with bronchopneumonia,to analyze the clinical value combined with the age and to provide the experimental basis for clinical diagnosis and treatment.Methods 100 children with bronchial pneumonia were selected.According to admission number,they were randomly divided into the study group and the control group,50 cases in each group.The control group received routine diagnosis and treatment.The study group was deteced blood calcitonin,blood routine,C-reactive protein level and diagnosed and treated combined with the age.The clinical curative effect,recovery time were observed.The referral rate,children fever,cough,X-ray pulmonary inflammation disappeared time,the average recovery time,and medical expenses were assessed and recorded.Results The cure rate of the study group was 80.0%(40/50),which was higher than 66.6%(33/50) of the control group,the referral rate of the study group was 6.0%(3/50),which was lower than 22.0%(11/50) of the control group,the differences were statistically significant (χ2 =8.61,8.95,all P<0.05).The medical expense of the study group was (3 273.15 ±260.35)yuan,which was lower than (5 426.42 ±238.20)yuan of the control group,the difference was statistically significant (t=11.47,P<0.05).The average recovery time of the fever,cough,X-ray pulmonary inflammation in the study group were (3.29 ± 0.48)d,(5.36 ±0.63) d,(4.17 ±0.57) d,(6.48 ±0.86) d,which were shorter than those of the control group [(4.51 ±0.41)d,(6.70 ±0.52)d,(5.84 ±0.61)d,(7.79 ±0.93)d],the differences were statistically significant (t=8.50,8.69,8.27,9.04,all P<0.05).Conclusion In basic hospitals,detection blood PCT,blood levels of C-reactive protein of children with bronchial pneumonia and combined with the age for diagnosis and treatment, the clinical curative effect is better, the improvement time of the clinical signs or symptoms is shortened, referral rate decreased,medical costs declined.It is worth popularization and application in the basic level hospital.