This paper gives a brief account of the development path of medical ethics in early ancient China by introducing medical ethics essence in the medical masterpieces of "Inquiries of The Yellow Emperor's Canon of Medicine" and "History Record",medical skills and medical ethics of distinguished doctors in ancient China such as Chun ru-yi and Zhang zhong-jing.As the essential element of ancient Chinese medical ethics,the simple medical ethics thought in Pre-Qin,Qin and Han Dynasties is also included in this paper in order to explore its realistic significance in improving current medical ethics of medical staff and currently tensional physician-patient relationship.

Si Bu Yi Dian is one of the most marvelous masterpieces in the development of Tibetan Medicine,which selectively absorbed the essence from medical masterpieces of Tibetan Medicine and Han medicine,concluded the clinical experience in Tibetan Medicine,and is closely connected with traditional Chinese medicine.Its account of medical ethics also shares a similar origin with its counterpart in traditional Chinese medicine.The Peace-making Marriage and cultural communications between Tang Dynasty and Tibetan Regime,and Tibetan Regime's emphasis on medical science are the two major reasons for the close connection between the medical ethics of Tibetan Medicine and that of traditional Chinese medicine.

OBJECTIVE: To establish a RP-HPLC method for concentration determination of m-nisoldipine (m-Nis) in the plasma of rhesus monkeys.METHODS: The analysis was performed on a C18 column at 30℃ with a mobile phase of methanol-water (63∶37) at a flow rate of 1.0ml/min.The detection wavelength was 236nm.The sensitivity was 0.05AUFS and the internal standard was nimoldipine.RESULTS: The detectable concentration of m-Nis showed good linearity in the range of 1.75～ 448?g/L.The average recovery of extraction was 84.1%(RSD=4.09%), and the average recovery of method was 98.7%(RSD=2.76%).The processed plasma samples remained stable in quality after having been stored for 7 days, and the plasma remained stable in quality through repeated freeze thawing or stored at low temperature.CONCLUSION: The present method is highly sensitive and reproducible, as well as convenient, which can be used for concentration determination of m-Nis in the plasma of rhesus monkeys.

It is difficult to treat the internal carotid arterial (ICA) wall disease between C2 to C7 segment ( the definition of ICA by E. Bouthillier,1996) with present interventional radiological measurements , includling pseudoaneurysm, giant or wide neck aneurysm and complicated carotid cavernous fistula. Some literatures have reported a few cases treated with coronary covered stent (e.g. Jomed coronary stent, Symbiot coronary stent), with favorable results . However, these kinds of coronary covered stents are too rigid, with uneasinees to pass through in tortuous ICA, and often resulting in injury of vascular wall. The utility of covered stent in intracranial artery also caused controversies of exclusion of origins of arterial branches. We analyzed the functional anatomy of ICA and reviewed our experimental results and primarily clinical application on professional intracranial covered stent with special designed structure and delivery system for ICA, in order to explore the possibility of utility of covered stent in intracranial arteries.

Glutamate is a major excitatory neurotransmitter in the central nervous system(CNS)and plays an important role in neuronal damage induced by cerebral ischemia. Several mechanisms contribute to modulation of glutamate release during cerebral ischemia, such as vesicular release dependent on calcium, release by reversed operation of glutamate transporters, release through swelling-activated anion channel and receptor-modulating release, etc. This review addresses the mechanisms of glutamate release during cerebral ischemia.

Objective:To explore the therapeutic effect and safety of oral ibuprofen (INN)on patent ductus arterio-sus (PDA)in neonates.Methods:A total of 160 neonates,who hospitalized in our hospital and were diagnosed as PDA by color echocardiography from Feb 2011 to Dec 2013,were enrolled.According to number table method, they were randomly and equally divided into high dose group (received INN 10mg/kg on the first day,then 5mg/kg on the second and third day)and low dose group (received INN 5mg/kg for 3d).PDA closure was observed,com-pared and analyzed between two groups after INN therapy.Results:After INN therapy,PDA closed in 57 cases (71.3%)in high dose group,it was significantly higher than that of low dose group (48.8%,39/80),P <0.01;there were no significant difference in incidence rates of adverse reactions between two groups (P >0.05 all).Con-clusion:High-dose ibuprofen possesses better therapeutic effect on patent ductus arteriosus in neonates;its adverse reactions are few;which can avoid postoperative pain in partial children.

Objective To observe the therapeutic effects of Reduning combined with montmorillonite powder for infantile viral enteritis. Methods A total of 136 patients with infantile viral enteritis in Shanxi Tongchuan Mining Bureau Central Hospital pediatric clinic from August 2010 to October 2013 were selected and divided into two group by random number table method, a Reduning group (65 cases) and a combined treatment group (71 cases). The Reduning group was treated with Reduning injection and the combined treatment group was treated with Reduning injection plus oral montmorillonite powder. The total efficiency, improvement of symptoms and staying hospital time were compared between the two groups. Results The total effective rate in the combined treatment group was significantly higher than that in the Reduning group (97.1% vs. 59.9%, χ2=28.696, P<0.05). The fever clearance time (2.96 ± 1.32 d vs. 3.84 ± 1.94 d; t=2.587, P=0.011), the time to stop diarrhea (3.12 ± 1.44 d vs. 3.95 ± 1.97 d;t=2.340, P=0.022) and staying hospital time (4.60 ± 1.62 d vs. 5.86 ± 2.35 d;t=3.044, P=0.003) in the combined treatment group were all shorter than those in the Reduning group. Conclusions Reduning combined with montmorillonite powder is more effective in the treatment of infantile viral enteritis than Reduning alone, which shortens the course and staying hospital time.

Phenotypic conversion process of cells in blood vessels occurred after percutaneous transluminal angioplasty (PTA), which is similar to “recall” of angiogenesis. This article is an attempt in reviewing the major themes and more recent findings dealing with the phenotypic conversion and cellular source in three layers of arterial wall after PTA in the adult.

Objective To discuss the application of nursing care in CT-guided percutaneous biopsy of the pancreas.Methods The perioperative nursing measures were carried out in 21 patients receiving percutaneous biopsy of the pancreas under CT-guidance.Active,effective and comprehensive nursing procedures were adopted to closely cooperate with the whole process of percutaneous biopsy as far as possible.Results All the patients could actively cooperate with the physician during the whole process of percutaneous biopsy and the surgery was successfully completed in all patients.The technical success rate with only single puncture was 100%.No obvious complications occurred after the procedure.Conclusion In order to ensure that the patient will be able to cooperate with the CT-guided percutaneous biopsy of the pancreas,that the operation time can be shortened and that the postoperative complications can be avoided,perioperative nursing care is indispensable.

Objective To set up an isolated limp perfusion (LIP) model of rabbit approximately asin the physiological state. Methods Measuring and calculating the average speed of blood circulation in rabbit's femoral artery with ultrasound, building up an isolated limp of perfusion system with a mini membrane oxygenator and a mini pump. Observing the values of blood analyses (pH, PO 2 and PCO 2) at prior , mid and post operation with differential exchanging speeds of oxygen, and probabilities of circulation failure with differential blood flow speeds, and the glucose change at several points of time and the difference between the groups with and without compensating glucose, and the dimensions of hind leg prior and post operation. Results Results of ultrasound showed that there was no difference in parameter between bilateral femoral arteries giving no effect on the results of differential groups. Total average flow speed was (12.0?1.8) ml/min. Blood analysis: the perfusion without oxygen exchange showed pH was lower than preperfusion and physiological low threshold. PO 2 was below the normal standard, PCO 2 was higher than prepefursion and physiological upper threshold. 100ml/min of oxygen exchange showed pH, PO 2 and PCO 2 were rearly normal post perfusion and 200ml/min group showed pH and PO 2 obviously higher than the normal physiological value. The gulcose was lower than the normal at 30min after perfusion, but could be recoveried under the compensation of glucose. There was significant difference between the groups processing with and without glucose. There was no circulation failure when the flow speed was in 10ml≤V