Cerebral palsy (CP) is a essential disorder result in disability of children. Various treatments, especially rehabilitation, have been used and made some success for CP. This paper reviewed a number of literatures published last decade. The level of evidence and recommendation grade of various treatments was evaluated according to Cochrane.

Proposed definition of cerebral palsy(CP) is a group of disorders of the development of movement and posture, that are attributed to non-progressive disturbances that occurred in the developing fetal and infant brain. Types of cerebral palsy are divided into spastic(diplegia, hemiplegia, quatriplegia), dyskinetic(athetotic, dystonic), ataxic (simple ataxia, ataxic diplegia), and mixed CP(primarily spasticity with athetosis).

Objective To investigate the clinical and intellectual characteristics of children with cerebral palsy of ataxia type.Methods Twenty-one children with cerebral palsy of ataxia type were evaluated by the illness history,clinical physical examination,brain MRI scan and intellectual assessment.Results Delayed motor milestones and dysfunction of balance were found in these children,and 80.9% of brain MRI scan was abnormal as cerebellar damage,and delayed intellectual ability found in these children was ameliorated as improvement of motor function.Conclusion Cerebral palsy of ataxia type is mainly caused by cerebellar damage manifests as delayed motor function,dysfunction of balance and mental retardation.

Objective To investigate the changes of the gray matter in patients with rheumatoid arthritis (RA) based on the voxel based morphometry (VBM).Methods 35 patients with RA and 30 healthy volunteers with age,sex and education level matched performed a high-resolution 3D-T1-weighted whole brain structural scan by GE Signa HDxt 1.5T MRI scanner.The high resolution T1WI images were preprocessed by the VBM 12 implemented in the SPM 12 software to display the gray matter structures of the RA patients and the healthy volunteers.T test was used to compare the morphological changes of gray matter between the RA patients and the volunteers.Results The gray matter volume gray matter volume in the right lentiform nucleus,left frontal lobe and left cerebellum posterior lobe significantly decreased in RA patients,and their gray matter volume had no correlation with the clinical indications.The increase of gray matter volume was not found in the RA patients.Conclusion RA patients show decreased gray matter volume in several cerebral regions,which suggests that RA can lead to the brain structural abnormalities.VBM can provide an objective imaging evidence to evaluate the cerebral morphological abnormalities of RA.