Objective:To investigate the influence of auxiliary application of Xuesaitong injection on blood coagulation indices and thromboembolic complications in the patients after finger replantation. Methods:Totally 64 patients with finger replantation were cho-sen from March 2012 to March 2014 in our hospital and randomly divided into the control group (32 patients) treated with low molecu-lar weight heparin and Xuesaitong group (32 patients) treated with Xuesaitong injection additionally. The clinical curative effect, sur-vival time of finger replantation, the levels of blood coagulation indices before and after the operation and the incidence of thrombotic complications in both groups were compared. Results: The clinical curative effect of the control group and Xuesaitong group was 68. 75% and 93. 75, respectively, and that of Xuesaitong group was significantly better than that of the control group (P<0. 05). The survival time of finger replantation of the control group and Xuesaitong group was (9. 44 ± 1. 56)d and (6. 72 ± 2. 28)d, respectively, and that of Xuesaitong group was significantly better than that of the control group (P<0. 05). The levels of blood coagulation indices on 1d, 4d and 7d after the operation in Xuesaitong group was significantly better than those in the control group and those before the treatment(P<0. 05). After the treatment, gastrointestinal hormone levels in Xuesaitong group was significantly better than those in the control group(P<0. 05). The incidence of thrombotic complications in the Xuesaitong group was significantly better than that of the control group(P<0. 05). There was no significant difference in the adverse effects between the two groups (P>0. 05). Conclusion:Auxiliary application of Xuesaitong injection in the patients after finger replantation can efficiently speed up the replantation survival process and improve blood coagulation indices after the operation, which is helpful to reducing the risk of thrombotic complications.