Objective To evaluate the diagnostic value of three-dimensional CT(3DCT)in atlantoaxial lesions.Methods The findings of 3DCT were analyzed and compared with conventional CT and radiography in 124 patients with atlantoaxial disease.Results 124 cases of atlantoaxial lesion included fracture in 42,atlantoaxial rotatory dislocation in 73,hypoplasia of the dens in 4,and congenital atlantoaxial deformity in 5.Among the 124 cases,89 cases were diagnosed by X-ray,109 cases by conventional CT,121 cases by MIP,122 cases by SSD,124 cases by MPR and VR.Conclusion 3DCT can find the slight rotatory dislocation,so it is the most effective means for the diagnosis of atlantoaxial rotatory dislocation.3D and MPR of spiral CT are useful in the diagnosis of atantoaxial fracture.Combining conventional CT and X-ray film with 3DCT can improve the acuracy of the diagnosis.

Objective: To develop the national norms of ISCA (intelligence scale for Chinese adult) for urban adults aged 16 to 64 years and examine its psychometric characteristics. Methods:The ISCA standardization was completed on 1600 adult subjects. Year 2000 Census data was applied to the standardization sample in order to correctly represent individuals by age, gender, educational level, geographic region, and occupation. Results:The ISCA had good reliability( test-retest coefficients of Full scale IQ was 0.96, the average spilt-half reliability for the IQ scales ranged from 0.93 to 0.96 and the average standard error of measurement of subtest ranged from 1.04~1.88, rater reliability 0.91~0.96). The total score of ISCA relates that of the WAIS-RC, WAIS-III revised in Taiwan, and CRT-C2 are 0.94, 0.90, 0.69, respectively (P

Objective To assess dietary glycemic load (GL) in young adult males with acne vulgaris and to evaluate its association with severity of skin lesions,in hope to provide evidences for comprehensive treatment of acne vulgaris.Methods The Global Acne Grading System (GAGS) was used to evaluate the severity of acne,and food frequency questionnaire (FFQ) and 24-hour dietary recall (24-HDR) to assess GL.Differences in GL and body mass index (BMI) were assessed by t test and analysis of variance,and Logistic regression analysis was conducted to analyze the factors influencing BMI and GL.Results This study included 99 young adult males with acne vulgaris who were 19-24 years old.Logistic regression analysis revealed that GL was the risk factor of BMI,and higher GL was always associated with increased BMI (β3 =1.119,P ＜ 0.05,OR =3.062,95％ confidence intervals:1.044-8.986).No factors were found to have influences on GL.The patients with a disease duration of ＞ 6 months showed a higher GL (t =2.947,P ＜ 0.01),but similar BMI (t =0.798,P ＞0.05) compared with those with a disease duration of ≤6 months.Significant differences were observed in GL (F =76.296,P ＜ 0.01),but not in BMI (F =3.142,P ＞ 0.05),among the three groups of patients with different GAGS score.GL was higher in patients with GAGS score of ≥39 than those with GAGS score of 1-18 (P ＜0.01) and GAGS score of 19-30 (P ＜ 0.01),and higher in patients with GAGS score of 19-30 than in those with GAGS score of 1-18 (P ＜ 0.01).Conclusion GL is positively correlated with the severity of lesions and disease duration in young adult males with acne vulgaris.

Objective To study multi-slice spiral CT(MSCT) manifestations of spondyloschisis.Methods 40 patients with spondyloschisis were examined with MSCT scan and 3D reconstruction.Results In the 40 cases,CT scans showed spondyloschisis of the lumbar in L_2(1/40),L_3(1/40),L_4(10/40),L_5 spondyloschisis of the lumbar in L_2(1/40),L_3(1/40),L_4(10/10),L_5(28/40).MSCT displayed:the ring-scission sign(100%),the pseudo-bulging of lumbar intervertebral disc and the elongated sign of spinal canal(95%),and the wavered sign of vertebral body(12.5%).The location,shape of spondyloschisis and the degree of spondylolisthesis were demonstrated by MSCT on multiplanar and 3D.Conclusion The ring-scission sign is the specific sign in diagnosing the spondyloschisis of the lumbar by MSCT.It is of significant value in the detection of spondyloschisis

Objective To observe the effects of indole-3-carbinol on neointimal hyperplasia and restenosis of rat artery after balloon injury and the possible mechanisms.Methods Balloon dilation was used to establish the neointimal injury model of left carotid artery in rats.Twenty Sprague-Dawley rats were randomly divided into single balloon dilation group(control group)and balloon dilation followed by indole-3-carbinol therapy group(therapeutic group).After balloon dilation,indole-3-carbinol(12.5,25,50 mg/d)was applied to the rats for 7 days respectively.The rats were killed two weeks after balloon dilation and the injured vascular specimens were harvested for pathologic examination and immunohistochemical staining.Results ①The neointimal thickness,neointimal area in the therapeutic groups were significantly less than that of the control group(P

BACKGROUND:Data suggested that there were 24.5 million of human immunodeficiency virus (HIV) infected women in 16 countries in southern Sahara Africa.OBJECTIVE: To survey the HIV infection status among women in reproductive age in Mauritania so as to provide research direction and basic data for prevention and treatment of immunodeficiency diseases.DESIGN: Random sampling survey.SETTING: Epidemic Disease & Health Statistics Department of Radiation Medicine and Public Health College of Suzhou University;Institute of Iodin Absence of Harbin Medical University;and Public Health College and Epidemic Disease & Health Statistics Department of Harbin Medical University.PARTICIPANTS:The survey was conducted in the 14 main cities of the whole country from March to June 2001. Inclusion criteria: Women were in reproductive age, aged 15-49 years, from Mauritania; and all told the fact.Exclusion criteria: Women refused survey and not in reproductive age were excluded.Among 331 548 women,4 000-6 000 samples were surveyed and the sampling rate was 1.2％-1.8％.METHODS: Venous blood and isolated sera of women in reproductive age were collected. Sera were detected by ELISA test and confirmed by Western Blot test in order to know HIV infection and its subtypes.The detection rates of different population and cities were calculated and made statistical analysis.MAIN OUTCOME MEASURES: The infection and subtypes of HIV; infected rate of HIV among different crowd in different cities.RESULTS: Among 4 648 women in reproductive age in 13 provinces, 24infected cases aged of 15-49 years were found with the infected rate of 0.516％,of them 22 cases were infected with HIV-1 and 2 cases were in fected with HIV-2. The detection rates were 0.500％-1.010％ (5 cities), 0-0.500％ (3 cities) and 0％ (5 ities) respectively. The age of 95.83％ of the total infected cases was 15-29 years. The number of the HIV-infected cases was about 1 400 persons among women in reproductive age in 13 main cities.CONCLUSION: The total HIV-infected detection rate was 0.516％ among women in reproductive age in 13 main cities of Mauritania.HIV-1 2 was the dominant subtype. HIV infection was different among regions. HIV-in fected cases aged 15-29 constituted more than 95％ of the total cases. The prevalent trend of AIDS was in the stage of transmission after importing.

Objective To investigate the value of CT pulmonary artery obstruction index (PAOI)in evaluating the severity in patients of pulmonary embolism (PE)by a correlation study between CT PAOI and right ventricular function parameters and arterial blood gas analysis index.Methods CT PAOI,right ventricular function parameters and arterial blood gas analysis index were collected from 70 patients with PE,who had received CT pulmonary angiography (CTPA)examination in our hospital.Spearman rank correlation coefficient was used to evaluate the correlation between the PAOI and right ventricular/left ventricular maximum short axis diameter ratio (RVd/LVd),main pulmonary artery diameter (MPAd),superior vena cava diameter (SVCd),arterial oxygen partial pressure (PaO2 ),arterial carbon dioxide into pressure (PaCO2 ),oxygen saturation (SaO2 ),Alveolar arterial oxygen partial pressure difference (P(A-a)O2 ).Results PAOI and PaO2 were negative correlation,the correlation coefficient was -0.442;PAOI and RVd/LVd, MPAd,SVCd,P(A-a)O2 were positively related,correlation coefficients ranged between 0.163-0.675;PAOI was not related to SaO2 .Conclusion CT PAOI can be used to evaluate the severity of PE,it is not consistent with the severity of the patient’s clinical condition.

Objective To evaluate the clinical application of multi-slice spiral CT(MSCT) and X-ray plain film in congenital scoliosis.Methods 40 cases with congenital scoliosis were undergone MSCT scan,the imaging data were reconstructed with maximum intensity projection(MIP),multiple planar reconstruction(MPR),surface shaded display(SSD) and surface volume rendering(SVR),the applied value of these various reconstructed images were analysed comparatively with X-ray plain film.Results Based on the preoperative X-ray plain films,the spinal formation failure,segmentation failure and mixed failure of spine were found in 18,15 and 7 cases respecitvely.However MSCT scan showed that 13 cases had formation failure,12 cases had segmentation failure and 15 cases were mixed failure of spine,and in combination with spinal bifida in 6,rib deformity in 8 and bony ridge inside vertebral canal in 4.The relative features of congenital scoliosis could be comprehensively evaluated by SVR images.Conclusion The reformatted images of MSCT is remarkedly superior to conventional X-ray images in judging the classification and area of spinal deformity accurately.

Objective To study the relationship between serum hepatitis B virus covalently closed circle DNA (HBV cccDNA) as well as liver function and liver tissue pathological changes in children with chronic hepatitis B.Methods One hundred and twenty-four HBV-DNA positive children with hepatitis B were enrolled.Among 124 patients,65 cases were HBV carriers,59 cases were chronic hepatitis (mild in 31 cases,moderate in 18 cases and severe in 10 cases).HBV cccDNA in serum and liver function were detected,46 of which underwent liver biopsy and liver tissue inflammation and fibrosis grading classification was made.Results In moderate and severe cases,positive rates of serum HBV cccDNA (77.8％,100％) were higher than those of the HBV carriers and mild cases (32.3％,54.8％) (x2 =25.429,P ＜ 0.01),indicating more severe illness in children,detection rate of serum HBV cccDNA was higher.ALT,AST,and TBIL were higher in serum HBV cccDNA positive group than those of negative group[(95.6 ± 18.2) U/L vs (52.5 ± 17.7) U/L,(88.8 ±20.3) U/L vs (48.4 ±21.4) U/L,(68.4 ±24.6) μmol/L vs (28.3 ± 23.9) μmol/L](t =15.572,10.750,17.067,P ＜ 0.01).Serum HBV cccDNA and liver inflammatory activity and fibrosis showed no significant correlationship.Conclusion Serum HBV cccDNA is a sensitive indicator of viral replication,the more severe the disease situation,the peripheral HBV cccDNA detection rate is higher.But it is not entirely consistent with liver inflammation and fibrosis,so it can not completely reflect the degree of liver damage.

Objective To investigate the clinical features, the video electroencephalography ( V-EEG) and synchronous electrocardiography ( ECG) changes in non-epileptic seizures and the significance of ECG monitoring in the diagnosis of epilepsy.Methods We collected 3 patients who came in a chief complaint of“episodes of unconsciousness with limbs twitch”, whose clinical features and EEG, ECG in longterm VEEG monitoring were analyzed.The 3 patients were followed up for at least 6 months.Results The 3 patients were all diagnosed as epilepsy in other hospital,and during the 24-hour VEEG monitoring in our hospital,2 patients showed abnormal cardiac rate and arrest during the attack and corresponding EEG changes after cerebral ischemia and hypoxia.After consultation with the department of cardiology, they were diagnosed as cardiac syncope episode and no attack showed up after the placement of pacemaker.The Q-T interval was prolonged in the other patient during the longterm ECG monitoring, after the coherence check who was diagonsed as severe hypocalcemia combined with myocardial damage due to a lower parathyroid function and had no attack after symptomatic treatment.Conclusions The synchronous ECG monitoring during the attack is of great significance in the differential diagnosis of epileptic and non-epileptic seizures. The ECG changes in patients with longterm VEEG monitoring should be focused on.It is necessary to add the early warning function to prevent the occurrence of accidents.