Objective To observe the effect of levocamitine on cardiac function of patients with dilated cardiomyopathy (DCM).Methods 40 patients with DCM were randomly divided into control group (n =20) and the experimental group(20 cases).Control group was given conventional drug such as digitalis,furosemide,benazepril hydrochloride,antisterone for treatment,the experimental group was given levocarnitine on the basis of control group.The treatment efficacy and the situation of cardiac function were compared between the two groups.Results The total effective rate was 95.0％ and 80.0％ in the experimental group and the control group,respectively,the difference was statistically significant(x2 =10.286,P ＜ 0.01).Compared with the control group,the parameters of stroke volume,cardiac output,ejection fraction,and left ventricular fractional shortening rate were significantly increased in the experimental group after treatment(all P ＜ 0.05).Conclusion Levocarnitine can improve cardiac function based on the conventional treatment.

High-dose melphalan (Mel) is considered as a current standard preparative regimen in autologous stem cell transplantation (ASCT) for multiple myeloma (MM). Irradiation in total body (TBI) combined with Mel is not superior to Mel alone, and the adverse reactions are increased at the same time. The efficacy of 200 mg/m2 Mel is much better than that of 100-140 mg/m2 Mel in young patients. Several regimens including MelBU, TBC, BCV, MET, MTC, MelBCNU, VMel, MTC as well as bendamustine have similar treatment outcomes compared with 200 mg/m2 Mel. Other strategies need to be evaluated in different trials.

Objective: To assess the feasibility and accuracy of real-time three dimensional echocardiography (RT-3DE) in quantitative evaluation of left ventricular (LV) volume and ejection fraction (EF) in patients with ventricular aneurysm and myocardial infarction. Methods: Twenty-three p atients with left ventricular aneurysm combined with myocardial infarction were examined by RT-3DE, two dimensional echocardiography Simpson's method, and M-mode Teichholz method separately. The following parameters: left ventricular end diastolic volume (LVEDV), end systolic volume (ESV), stroke volume (SV) and EF were obtained by each method and the results were compared with those obtained by left ventriculography (LVG). Results: The values of LVEDV, LVESV, SV, and EF determined by RT-3DE showed good correlations with those determined by LVG (r=0.92, 0.90, 0.88, and 0.91, respectively; P<0.001), with the values by RT-3DE slightly smaller than those by LVG(P>0.05). The values of LVEDV, LVESV, SV, and EF determined by Simpson's method also showed good correlations with those determined by LVG (r=0.85, 0.87, 0.86, 0.91, respectively; P<0.001), with the values by Simpson's method smaller than those by LVG (P<0.05 for LVEDV and LVESV). The values of LVEDV, LVESV, SV, and EF determined by M-mode Teichholz method also showed good correlations with those determined by LVG (r=0.73, 0.71, 0.70, 0.65, respectively; P<0.05), with the values by M-mode Teichholz method larger than those by LVG(P<0.05 or P<0.01). Conclusion: RT-3DE is a more accurate for evalua tion of LV volume and EF in patients with aneurysm combined with myocardial infarction.

Objective:To evaluate the effect of percutaneous coronary intervention (PCI) on mitral regurgitation (MR) in patients with acute myocardial infarction (AMI). Methods: A total of 213 AMI patients were divided int o PCI group (n = 87, PCI + medication) and medication group(n= 126, medication) according to the treatments they received. Echocardiographic examination was conducted in patients during admission and 6 months follow-up. Color Doppler was used to determine the degree of MR. Echocardiogram indices included MR degree, left ventricular end-diastolic diameter (LVEDd) ,left ventricular end-systolic diameter (LVEDs) ,left ventricular end-diastolic volume (LVEDV) ,left ventricular end-systolic volume(LVESV) ,and left ventricular ejection fraction (LVEF). Results: The overall incidence of MR was 28. 6% in 213 patients during admission. The MR incidence in patients with acute inferior myocardial infarction was higher than that in patients with other parts of infarction (34. 5% vs 22. 3% PO. 05), while the incidence in medication group increased significantly than that during admission(43. 7% vs 30. 2%,P

To improve flexibility and reliability of iris recognition algorithm while keeping iris recognition success rate, an iris recognition approach for combining SVM with ICA feature extraction model is presented. SVM is a kind of classifier which has demonstrated high generalization capabilities in the object recognition problem. And ICA is a feature extraction technique which can be considered a generalization of principal component analysis. In this paper, ICA is used to generate a set of subsequences of feature vectors for iris feature extraction. Then each subsequence is classified using support vector machine sequence kernels. Experiments are made on CASIA iris database, the result indicates combination of SVM and ICA can improve iris recognition flexibility and reliability while keeping recognition success rate.

Adolescent ; Adult ; Child ; Dexamethasone ; administration & dosage ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; administration & dosage ; Female ; Humans ; Male ; Middle Aged ; Phytotherapy ; Rhinitis, Allergic, Perennial ; therapy ; Volatilization

Serum prostate-specific antigen (PSA) is composed of the PSA precursor protein (proPSA) in the absence of the leader peptide induced by human kallikrein 2 (hK2). There are many forms of PSA in the blood, including free PSA and bound PSA. Serum proPSA, as a free PSA, has many isoforms, among which, [-2]proPSA (p2PSA) cannot be activated by hK2 and therefore exists stably in the blood. Serum p2PSA is a homologous isomer of PSA. Serum prostate health index and % p2PSA, as the derivative indexes of p2PSA and molecular markers associated with the development and progression of prostate cancer, can reduce serum PSA test-induced excessive diagnosis and treatment of the malignancy and improve the accuracy of its prediction. This review summarizes recent progress in the studies of serum p2PSA and its derivative indexes in prostate cancer.
Humans ; Male ; Prostate-Specific Antigen ; blood ; Prostatic Neoplasms ; blood ; immunology ; Protein Isoforms ; blood

Objective To compare the effect and safety of venlafaxine sustained-release tablet combined with Shuganjieyu capsule and venlafaxine sustained-release tablet used singlely in the treatment of moderate to severe poststroke depression.Methods 70 patients suffered from moderate to severe post-stroke depression were randomly divided into two groups,35 cases in each group.The patients in the control group were only treated with venlafaxine sustained-release tablet,and the patients in the study group were treated by venlafaxine sustained-release tablet combined with Shuganjieyu capsule.The treatment lasted 6 weeks.The therapeutic effect and safety were evaluated by the positive and negative syndrome scale of HAMD (17 items),and treatment emergent symptom scale of TESS.Results After treatment for 6 weeks,the total effective rate of the study group was 88.57％,which was significantly higher than 65.71％ of the control group (x2 =5.19,P ＜ 0.05).The HAM D score of the study group w.as (16.42 ± 6.07) points,and the HAMD score of the control group was(10.54 ± 5.23) points after 6 weeks.The difference was statistically significant between the two groups (t =4.34,P ＜ 0.01).The difference of TESS score between two groups was not significant(t =0.18,P ＞ 0.05).Conclusion Venlafaxine sustained-release tablet combined with Shuganjieyu capsule is effective and safe in the treatment of moderate to severe post-stroke depression.

On sjogrens' syndrome (SS) clinical treatment,most of the clinician focused on nourishing Yim to moisten dryness.In fact,Yang qi was the metabolic power of the human body fluid,exerting an important role in the incidence and prognosis of SS.For SS of Yang deficiency syndrome,water,Qi and fire can not be guided back to the kidney was the key cause,therefore,warming kidney Yang should be the therapeutic principle.Modified Yimhuo decoction can be used in its treatment.

Objective To explore the impact of placenta polypeptide injection on fracture healing time and the incidence of infec-tion in patients with limb fractures .Methods 138 cases with limb fractures admitted to our hospital from February 2010 to Febru-ary 2012 were randomly divided into two groups ,and each group had 69 patients .The control group was given conventional treat-ment while the observation group was given placenta polypeptide injection on the basis of the conventional treatment .The bone healing time and infection rates were observed .Results The limbs fracture healing time of observation group was significantly shorter than that of control group (P<0 .05) .The infection rate of observation group (1 .45% ) was significantly lower than that of control group (10 .14% ,P<0 .05) .Conclusion The placenta polypeptide injection for treatment of limb fractures can effectively decrease fracture healing time ,and significantly reduce the rate of infection .