1.Director Doctor Zhao Runchen Treat Cervical Spondylosis of Nerve Root Type
Journal of Zhejiang Chinese Medical University 2015;(9):710-712
Objective]To observe the clinical effect of chief physician Zhao Runchen’s therapy of nerve root type cervical spondylosis.[Methods]According to the random and parallel control test principles, 48 cases of patients with nerve root type cervical spondylosis were divided into treatment group and control group. The treatment group was treated with conventional massage combined with pulling therapy, and the control group was treated with conventional massage. After treatment every other day for 20 times, the clinical effect of the two groups and the visual analogue scale before and after treatment were observed.[Results]15 cases in the treatment group were cured, 6 cases improved, so the basic cure rate was 63%, and total effective rate was 88%. 11 cases in the control group were cured, 9 cases improved, so the basic cure rate was 46%, and total effective rate was 83%. Cure rate between the two groups had significant difference(P<0.01), and VAS score of both groups were significantly improved after treatment: the control group decreased significantly(P<0.05), and the treatment group showed extremely significant decrease(P<0.01). [Conclusion]Chief physician Zhao Runchen’s pulling therapy of nerve root type cervical spondylosis has a satisfactory basic cure rate.
2.Meta-analysis on effect of postoperative adjuvant chemotherapy for advanced gastric cancer
Chongqing Medicine 2014;(26):3445-3448
Objective To systematically analyze the effect of adjuvant chemotherapy after radical operation in advanced gastric cancer .Methods The related literatures published at home and abroad were retrieved from the electronic databases including CNKI ,PubMed ,Elsevier ,Springer ,Oxford from January 2003 to December 2013 ,then 11 articles of the randomized controlled trial (RCT) of the comparison between the postoperative adjuvant chemotherapy and simple operation were collected .The effect merging and the quantitative systematic evaluation in the aspects of the total survival ,disease free survival and relapse free survival were per-formed with RevMan5 .2 provided by the Cochrane collaboration network .Results 11 articles of RCT were included with 4 points and more by the Jadad scale ,involving 4 433 patients ,among them 2 203 patients with operation plus postoperative chemotherapy and 2 230 patients with surgery alone .The results analysis indicated that the postoperative adjuvant chemotherapy made the pa-tients to obtain the apparent benefit during survival period ,the significant difference had statistical significance .OS :HR= 0 .80 , 95% CI(0 .73 ,0 .88) ,P<0 .01 ;DFS :HR=0 .78 ,95% CI(0 .63 ,0 .97) ,P=0 .02 ;RFS :HR=0 .67 ,95% CI(0 .53 ,0 .85) ,P=0 .001 . Conclusion The postoperative adjuvant chemotherapy can make the patients with radical operation to obtain the apparent benefit during the survival period .The adjuvant chemotherapy of oral capecitabine plus oxaliplatin or oral Tegafur Gimeracil Oteracil Potas-sium after D2 radical operation may be the best scheme at present .
5.Diabetes hospitalization in Peking Union Medical College Hospital from 1995 to 2009
Chinese Journal of Clinical Nutrition 2010;18(2):72-76
Objective To analyze the hospitalization rates of diabetic patients in different departments in different years and compare the differences in hospitalization costs, length of stay, and mortality between diabetic and non-diabetic patients. Methods The clinical data of hospitalized patients from 1995 to 2009 in different departments of Peking Union Medical College Hospital were retrospectively analyzed. Patients were divided into three groups by calendar period (every five years) and into four groups by ages. Results A total of 500 523 patients were enrolled in this study. From 1995 to 2009, the hospitalization rates of diabetic patients increased from 2.85% to 7.65% , especially among patients who were treated in the departments of cardiology, ophthalmology,and vascular surgery. In 2009, the hospitalization rates of diabetic patients in the three departments were 29.36% , 24. 51% , and 21.25 % , respectively. The length of hospital stay was significantly longer among diabetic patients than among non-diabetic patients (P < 0. 001). The total hospital costs were also significantly higher among diabetic patients than among non-diabetic patients in all the period and age groups (P < 0.01 or P <0.001)except in 2000-2004 group and 2005 - 2009 group in 0 - 18 years group (P >0. 05). The hospital cost per day in diabetic patients was significantly lower than that in non-diabetic patients in all the period and age groups (P < 0. 05, P < 0. 01 or P < 0. 001)except in 1995-1999 group in over 65 years group (P > 0.05). The mortality rate of diabetic patients in the 1995-2004 in 0-18 years group was zero, and the mortality rates were not significantly different between diabetic patients and non-diabetic patients in 2005 -2009 group in 0-18 years group (P >0.05), and were significantly higher in diabetic patients than in non-diabetic patients in all other period and age groups (P <0.01 or P < 0. 001). Conclusions Diabetic inpatients tend to have a longer hospital stay, higher hospitalization rate, higher hospital costs, and higher mortality rates. A hospital-wide diabetes management mode should be developed to optimize its treatment.
6.Comparison of Hysteroscopic and Laparoscopic Treatment for Endogenous Type Cesarean Section Scar Pregnancy
Chinese Journal of Minimally Invasive Surgery 2015;(10):894-896
Objective To evaluate the safety and feasibility of hysteroscopy in the treatment of endogenous type cesarean section scar pregnancy (CSP). Methods Clinical data of 58 cases of CSP from August 2012 to February 2014 in our hospital were analyzed retrospectively.Thirty-one cases were treated by hysteroscopy,while 27 cases were treated by laparoscopy.The intraoperative blood loss,operation time,postoperative hospital stay,postoperative drainage of uterine cavity,β-hCG level resolution time and time to menstruous restoration were compared between the two groups. Results The intraoperative blood loss,operation time,length of hospitalization after operation,and time to menstruous restoration were statistically lower in the hysteroscopy group than those in the laparoscopy group [(109 ±59)ml vs.(143 ±63)ml,t =-2.121 ,P =0.038;(43.7 ±17.5)min vs.(100.8 ±18.8)min,t =-1 1 .974,P =0.000;(3.8 ±0.7)d vs.(4.5 ±0.6)d,t =-4.057,P =0.000;(43.8 ±3.9)d vs.(45.9 ±3.8)d,t =-2.070,P =0.043].There were no significant differences in postoperative drainage of uterine cavity and β-hCG level resolution time between the two groups [(22.1 ±2.8)ml vs.(23.6 ±3.2)ml,t =-1 .904,P =0.062;(20.5 ±7.7)d vs.(22.9 ±9.3)d,t =-1 .075,P =0.287]. Conclusion Hysteroscopy has advantages of less intraoperative blood loss,shorter hospitalization time and quicker recovery in the treatment of endogenous type CSP.
8.Age-related clinical characteristics and differences of refractory nasal bleeding site
Chinese Archives of Otolaryngology-Head and Neck Surgery 2017;24(6):309-311
OBJECTIVE To investigate the distribution and regularities of intractable nasal bleeding site in different aged patients.METHODS The clinical data of 149 patients with intractable epistaxis were reviewed respectively.RESULTS Of the 149 patients, 110 cases were male and 39 cases were female with a age ranged from 18 to 87 years. They were divided into young group (39y or less), middle age group(40~59 y) and elderly group(60y or older), and there were 36, 52 and 61 cases in each group respectively. Hemostasis was performed with local anesthesia or general anesthesia under nasal endoscope. There were 145 cases with definite bleeding site, and electrocautery or micropacking was used for stop the bleeding. There were 4 cases without definite bleeding site. The bleeding site was on the posterior fornix of inferior meatus in 22 cases(61%), posterosuperior of middle nasal meatus in 13 cases(36.1%) and olfactory cleft of nasal septum in one case(2.7%) in young group; The bleeding site was on the posterior fornix of inferior meatus in 23 cases(44.2%), posterosuperior of middle nasal meatus in 10 cases(19.2%) and olfactory cleft of nasal septum in 17 cases(32.7%) in the middle age group; In the elderly group, the bleeding site was on the olfactory cleft of nasal septum in 37 cases(60.6%), posterosuperior of middle nasal meatus in 15 cases(24.6%) and posterior fornix of inferior meatus in 7 cases(11.5%).CONCLUSION In patients with refractory nasal bleeding, the majority responsible vessel was sphenopalatine artery or its branches in young and middle-aged patient and branches of anterior/posterior ethmoidal artery in elderly patients. Along with the increase of age, the sphenopalatine artery branch bleeding decreased, but the branches of anterior/posterior ethmoidal artery bleeding increased.