This article analysis the present situation of less than 35 years of Sun Yat-sen university youth scientific and technological personnel,they declare、undertake to support basic research based science fundation related cases,discusses the science foundation for their assistance and training problems,put forward youth scientific talents to suit the science funds development requirements to promote their development proposals

OBJECTIVE:To compare the effects of2different treatment methods on the assaying of triptolide alcohol in tripterygium wilfordii cut crude drug.METHODS:After concentration,tripterygium wilfordii cut crude drug water decoction underwent column chromatographic separation after adsorption with neutral alumina(Method1)and neutral alumina column chromatographic separation after ethanol precipitation and extraction by chloroform(Method2),respectively.Triptolide alcohol was determined by HPLC and the assaying result underwent pairing and t tests.RESULTS:There was significant difference between the2methods with the content determined by Method1significantly higher than that by Method2(P

Alteration of H-and M-isozymfs of Lactic Dehydrogenase(LDH) were observed in the various tissues after exposing the rats to 50ppm and 250ppm of sulfur dioxide. These isozymes of the respective tissue were separated by Diethlaminoethyl(DEAE)-cellulose from tile tissue homogenates of brain, lung and muscle, presenting the activities by rate of reduction of nicot inamids-adenine-dinucleotide (NAD+). Pure LDH and the coenzyme NAD (NAD) were directly treated with sulfur dioxide in vitro order to find out the direct to sulfur dioxide on LDH and NAD+ and the results were as follow. 1. In the normal tissues, the H-isozyme activity was dominant in the brain and heart, and tole M-isozyme in the muscle. 2. In the lung tissue of normal rats, there was no different between tole activity of H-and M-type of LDH. 3 When rats inhale sulfur dioxide gas in concentration of 50ppm and 230ppm, it appeared that the H-type tend to be suppressed in aerobic tissues and the M-type in anaerobic tissues. 4. In the lung tissue exposed to sulfur dioxide, both the LDH activities were suppressed. 5. It seems that LDH and the coenzyme (NAD ) are not directly affected by exposing in sulfur dioxide gas.
Animals ; Brain ; Heart ; Isoenzymes ; Lung ; NAD ; Rats ; Sulfur Dioxide* ; Sulfur*

Epigenetics is the study of genomic structural modifications that affects gene expression without DNA sequence change.Epigenetic mechanisms for the regulation of gene expression include DNA methylation,histone modifications,and microRNAs.DNA methylation may contribute to silencing gene expression which is a major mechanism of epigenetic gene regulation.DNA methylation regulatory mechanisms in lens development and pathogenesis of cataract represent exciting areas of research that have opened new avenues for association with aging and environment.This review concludes current understanding of the major mechanisms and function of DNA methylation in lens development,pathogenesis of age-related cataract,secondary cataract and complicated cataract.By understanding the role of DNA methylation in the lens disease and development,it may help to develop a new therapeutic approach to clinical treatment of cataract.

AIM: To explore the effect of radial axial incision on corneal astigmatism after phacoemulsification.METHODS: Totally 60 cases (62 eyes) of cataract patients were selected from our hospital, divided into Group A and Group B randomly.Two groups were both required to have a corneal incision, while Group A took it in the maximum corneal refractive radial axial and the Group B took it in the traditional temporal side (right eye) or nasal side (left eye).At the same time two groups received phacoemulsification and foldable intralocular lens (IOL) implantation.We measured their date before surgery, after surgery in 1d, 1wk and 1mo respectively with CT200 corneal topography measurement.The date was compared in two groups of corneal astigmatism, surgically induced astigmatism and visual acuity.According to the corneal astigmatism and axial, surgically induced astigmatism was calculated.RESULTS: Group A and Group B were compared in age, gender, lens nucleus hardness, visual acuity, corneal astigmatism before the surgery, which has no statistically significant differences (P>0.05).Postoperative visual acuity of both groups was higher than preoperative (P<0.05), but the difference was not statistically significant in 1d, 1wk and 1mo after surgery in two groups (P>0.05).Corneal astigmatism was not statistically significant in two groups at 1d after surgery (P>0.05).The corneal astigmatism was significantly less in Group A than that in Group B in 1wk and 1mo after surgery, and the difference was statistically significant (P<0.05).After the surgery for 1wk and 1mo, the surgically induced astigmatism of Group B was significantly higher than that of the Group A, with the difference was statistically significant (P<0.05).CONCLUSION: Making clear corneal incision along the maximum curvature of the cornea in cataract surgery can make the corneal astigmatism and the degree of astigmatism less after surgery.

Our objective is to enable the blind to use smartphones with touchscreens to make calls and to send text messages (sms) with ease, speed, and accuracy. We believe that with our proposed platform, which enables the blind to locate the position of the keypads, new games and education, and safety applications will be increasingly developed for the blind. This innovative idea can also be implemented on tablets for the blind, allowing them to use information websites such as Wikipedia and newspaper portals.
Visually Impaired Persons ; Cell Phones ; Inventions

[Objective]To find the relationship between total content of salvianolic acids and single compound by comparing the determining method of colorimetery with HPLC.[Methods]To respectively research the methodology,then compare the contents by different extracting methods with raw material from different regions.[Results]The two methods were reliable,the contents had the positive relationship.[Conlusion]The content of total salvianolic acids or sal B could be determined and deduced by only one method.

The increasing complexity of moral education atmosphere in colleges and universities makes it even moreimportant to better the function mechanism of potential education. This article first defines the potential and its functionmechanism,and then expounds the necessity of improving it , and at last puts forward some ideas and assumption on howto make it efficient and excellent.

An innovative educational model characterized as interesting-guiding is created in the acupuncture educational practice for foreign students. According to the innovative educational theories, teaching orders are rearranged, new teaching methods are used, and passive indoctrination is changed into creative studies and discussion, thus the educational quality is improved.

The development of the courseware of cardiac auscultation was introduced in this article.