1.Characteristics of Heath-Carter somatotype development in Dong students from Hunan province
Jianhui PI ; Yizhong WU ; Mingzhi LEI
Chinese Journal of Tissue Engineering Research 2008;12(20):3997-4000
BACKGROUND: There are many methods for studying the somatotype of adults or children. Among them, Heath-Carter somatotype method is a comprehensive evaluation method. Using this method, 10 items of anthropometric indicators are selected and 3 factors which could be gotten to represent relative content of body fat, growth degree of skeletal muscle and relative height and thinness of body (relative line degree), are calculated, respectively.OBJECTIVE: To analyze the rules and characteristics of somatotype development in Dong students from Hunan province, so as to supplement the essential data for physical anthropology.DESIGN, TIME AND SETTING: A cross-sectional investigation was performed at the Department of Biological Engineering, Huaihua College of Hunan Province in May 2006.PARTICIPANTS: A total of 989 Dong students (boys 492, girls 497), aged 7 to 17 years, were selected from the primary schools or middle schools of Tongdao Dong Nationality Autonomous Country in Hunan province and recruited into the present study. All the selected students were verified healthy by physical examinations at school. The subjects were divided into two groups by gender, and each group was divided into 11 subgroups according to the age.METHODS: By Heath-Carter somatotype method, 10 anthropological indexes were measured. Each indicator was measured twice and the average value was selected. The above-mentioned data were input into the computer to form a database. The following indicators were calculated in turn: 3 factors on somatotype, coordinate values of X and Y on somatotype chart, mean of dimensional distances from the average somatotype to all somatotypes in the sample, difference between the two somatotypes in three-dimensional space and frequency distribution of each somatotype.MAIN OUTCOME MEASURES: Height, body mass, upper arm circumference, calf circumference, intracondylar diameters of humerus and femur, skinfold of brachial triceps, subscapular skinfold, skinfold of anterosuperior iliac spine, skinfold of gastrocnemius muscle.RESULTS: All 989 students were included in the final analysis. The dynamic range of the average value of endomorphic factor was 1.2-1.9 and 1.3-4.1, and that of mesomorphic factor was 4.2-5.1 and 1.9-3.0, and that of ectomorphic factor was 2.8-3.7 and 2.6-3.9 for the boys and the girls, respectively. Statistical analysis revealed that there was significant difference in the average value of mesomorphic factor by gender in each age (P<0.05-0.01). The average endomorphic factor of the girls was obviously higher than that of the boys in each age (P<0.01) except 7 to 11 years old. The average ectomorphic factor of the girls was higher than that of the boys before 13 years old and it was contrary after 13 years old. There was significant difference of average ectomorphic factor between beys and girls only in 9,11 and 15 to 17 years old (P<0.05-0.01). The results of t-test showed that there was significant difference for the somatotypes by gender in each age (P<0.05-0.01). The distribution of girl somatotype demonstrated a dynamic process from 7 to 17 years old, which demonstrated balanced mesomorphy-ectomorphy changed to balanced ecdomorphy, ectomorphy-ectomorphy, balanced endomorphy-ectomorphy and balanced endomorphy in turn. But distribution of boy somatotype was relatively stable, and average somatotype was mesomorphy. Cluster analysis revealed that there was obvious difference of congenital somatotype between Dong students and other 9 populations. During puberty, the somatotype feature of Dong boys was more close to that of Korean boys (SAD=0.37), but which was more far to that of Han boys in the city (SAD=2.15). The somatotype feature of Dong girls was more close to that of Zhuang girls (SAD=0.71), but which was more far to that of Korean girls (SAD=2.35) and Miao girls (SAD=2.10).CONCLUSION: The congenital somatotype of Dong students has its unique characteristics. There is obvious difference in somatotype characteristics between boys and girls.
2.Therapeutic Observation of Zhuang’s Medicated Thread Moxibustion plus Acupoint Thread Embedding for Allergic Rhinitis
Xijuan ZHANG ; Xilin WANG ; Yizhong WU ; Yilan WEI ; Gang LIU
Shanghai Journal of Acupuncture and Moxibustion 2015;(2):128-129
Objective To observe the efficacy of Zhuang’s medicated thread moxibustion plus acupoint thread embedding in treating allergic rhinitis.Method By using random number table, 103 patients with allergic rhinitis were randomized into a treatment group (n=53) and a control group (n=50). The treatment group was intervened by Zhuang’s medicated thread moxibustion and acupoint thread embedding, while the control group was by acupoint thread embedding alone. The subjects were treated for 6 courses with a one-month follow-up. The therapeutic efficacies were compared between the two groups.Result The total effective rates were respectively 94.3% and 80.0% in the treatment group and control group.Conclusion Zhuang’s medicated thread moxibustion plus acupoint thread embedding has significant advantage in improving the symptoms of allergic rhinitis.
3.Percutaneous radiofrequency thermocoagulation for the treatment of different types of trigeminal neuralgia: Evaluation of quality of life and outcomes.
Yizhong, HUANG ; Jiaxiang, NI ; Baishan, WU ; Mingwei, HE ; Liqiang, YANG ; Qi, WANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2010;30(3):403-7
Radiofrequency thermocoagulation (RFT) of the gasserian ganglion is a routine and effective technique for the treatment of classical trigeminal neuralgia (CTN). In this study we compared its efficacy in patients with CTN and atypically symptomatic or mixed trigeminal neuralgia (MTN). Fifty-seven patients were treated with RFT for trigeminal neuralgia from June 2006 to February 2009. Thirty patients had CTN, and 27 had MTN. Outcomes were measured by using the visual analog pain scale (VAS) and patients' reports of quality of life (QOL), medication usage, and complications over a follow-up period of up to 3 years. Our results showed that the patients with MTN were younger, tended to have bilaterial involvement of the first division, and were unresponsive to treatment. All surgeries were completed smoothly. About 86.7% CTN patients and 48.1% MTN patients responded immediately to RFT. The VAS scores were significantly higher in the CTN group than in MTN group (P<0.05). Kaplan-Meier curves showed that 1-year, 2-year, and 3-year pain relief rates were 76.7%, 73.3%, and 73.3% in the CTN group and 46.6%, 41.4%, and 41.4% in the MTN group, respectively. The rates of pain relief for both groups leveled off at 2 years. Complications included numbness, dysesthesia, and anesthesia dolorosa. RFT did not cause any deaths and complications were low. The treatment was very effective for CTN and, to some degrees, effective for MTN. If numbness, dysesthesia, and anesthesia dolorosa are limited to the trigger area, QOL will be greatly improved.
4.Percutaneous Radiofrequency Thermocoagulation for the Treatment of Different Types of Trigeminal Neuralgia: Evaluation of Quality of Life and Outcomes
HUANG YIZHONG ; NI JIAXIANG ; WU BAISHAN ; HE MINGWEI ; YANG LIQIANG ; WANG QI
Journal of Huazhong University of Science and Technology (Medical Sciences) 2010;30(3):403-407
Radiofrequency thermocoagulation(RFT)of the gasserian ganglion is a routine and effective technique for the treatment of classical trigeminal neuralgia(CTN).In this study we compared its efficacy in patients with CTN and atypically symptomatic or mixed trigeminal neuralgia(MTN).Fifty-seven patients were treated with RFT for trigeminal neuralgia from June 2006 to February 2009.Thirty patients had CTN,and 27 had MTN.Outcomes were measured by using the visual analog pain scale(VAS)and patients' reports of quality of life(QOL),medication usage,and complications over a follow-up period of up to 3 years.Our results showed that the patients with MTN were younger,tended to have bilaterial involvement of the first division,and were unresponsive to treatment.All surgeries were completed smoothly.About 86.7% CTN patients and 48.1% MTN patients responded immediately to RFT.The VAS scores were significantly higher in the CTN group than in MTN group(P<0.05).Kaplan-Meier curves showed that 1-year,2-year,and 3-year pain relief rates were 76.7%,73.3%,and 73.3% in the CTN group and 46.6%,41.4%,and 41.4% in the MTN group,respectively.The rates of pain relief for both groups leveled off at 2 years.Complications included numbness,dysesthesia,and anesthesia dolorosa.RFT did not cause any deaths and complications were low.The treatment was very effective for CTN and,to some degrees,effective for MTN.If numbness,dysesthesia,and anesthesia dolorosa are limited to the trigger area,QOL will be greatly improved.
5.HIV antiretroviral therapy among blood donors: the impact on blood safety
Lilin WANG ; Fang ZHAO ; Zhengrong YANG ; Rui ZHU ; Yizhong LIU ; Linfeng WU ; Tong LI ; Tingting CHEN ; Jinfeng ZENG
Chinese Journal of Blood Transfusion 2024;37(2):138-144
【Objective】 To explore the the potential risks of antiretroviral therapy(ART) drugs on blood safety among blood donors in Shenzhen. 【Methods】 High pressure liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS) was used to measure ART drugs concentrations in the plasma of regular blood donors (negative control group, n=86) and anti-HIV positive individuals (experimental group, n=98, detected from approximately 440 000 blood donors during 2019—2023). The baseline plasma concentrations of ART drugs in the negative control group were clarified, and the impact of ART drugs on blood safety was analyzed. 【Results】 The baseline concentrations of ART drugs were not detected in 86 samples of negative control group. Four positive ART drugs samples were detected in 1∶2 pooled plasma samples of 98 anti-HIV positive blood donors plasma in the resolution test. The ART positive rate of anti-HIV positive donors was 4.08%, with tenofovir, lamivudine and efavirenz detected in three blood donors and lamivudine, lopinavir, ritonavir and zidovudine detected in one blood donor. 【Conclusion】 ART drugs were found among anti-HIV positive blood donors in Shenzhen. Additional research is needed to investigate the motivation of these specific donors, so as to ascertain the groups most susceptible to potential risks, and guarantee blood safety.
6.Effectiveness and safety of clinical use of stem cells and its implications for regulations
Xin LI ; Dongzhe LU ; Ping ZHOU ; Yizhong ZHANG ; Ang LI ; Xiaoxi WANG ; Zhaohui WU ; Di XUE
Shanghai Journal of Preventive Medicine 2022;34(11):1165-1169
ObjectiveTo analyze the effectiveness and safety of clinical use of different types of stem cells to provide evidence for governmental supervision of key issues in clinical utilization of stem cells. MethodsSix literature databases in China and abroad were searched for relevant literature published from January 2010 to July 2020, and a systematic review was conducted. ResultsThe study showed 72 studies concerning the effectiveness and safety of different types of stem cells in clinical utilization. Although clinical utilization of stem cells had some therapeutic effects for certain diseases, their long-term effect and safety need to be further evaluated, especially their potential risk of tumorigenicity. ConclusionTo protect the patients’ interest, physicians should fully weigh the benefits against the risks of clinical utilization of stem cells, and relevant governmental departments should strengthen supervision of ethics of clinical research and therapies involving stem cells as well as supervision of stem cell products.